Government of India sponsored M.Sc Marine Biotechnology at NUCSER
The Ministry of Science & Technology, Department of Biotechnology, Govt. of India has
approved Nitte University Centre for Science Education & Research (NUCSER) to offer
MSc in Marine Biotechnology. This recognition is awarded by the DBT, that will sponsor 10
students with a national fellowship of Rs.5,000/- per month.
Students will be selected through a National Level Graduate Aptitude Test-Biotechnology
(GAT-B) for all Biotechnology related courses in the country. The selection of students will
be based on merit in GAT-B.
The coordinator for the program is
Prof. (Dr.) Indrani Karunasagar
DIRECTOR (Projects & NuTEC, Nitte (DU)
Contact No. 9448479750
My specific area of research is to understand the role of ribosomes in bone marrow failure syndromes and cancer. Other areas of research include developing non-invasive and alternative DNA-based molecular tools for detection of specific mutations in cancer, developing transgenic zebrafish as cancer models and screening of natural antic-cancer compounds in zebrafish using HTS technology.
Deputy Director, Nitte University Centre for Science Education and Research, Mangaluru (Oct 2017 - To date)
Professor, Nitte University Centre for Science Education and Research, Mangaluru (Jan 2017- to date)
Associate Professor, Nitte University Centre for Science Education and Research, Mangaluru (Aug 2014- Dec 2016)
Senior Research Associate, Laboratoire de Biologie Moleculaire Eucaryote (LBME), UMR CNRS 5099, Toulouse, France (June 2012- June 2014)
Postdoctoral Fellow, Frontier Science Research Center, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan (May 2006- March 2012)
Ribosomes and human diseases
Cancer biology and genetics
Nucleolar proteins and their role in tumorigenesis and cancer
Rare genetic disorders affecting the bone marrow
Disease modeling in zebrafish
Molecular mechanisms of cancer and inherited bone marrow failure disorders
Role of ribosomes in cancer
Nucleolar proteins and their role in tumorigenesis
Small molecule screening in zebrafish
Deputy Director, NUCSER
Member, IQAC, NUCSER
Member Secretary, Board of Studies, NUCSER
Member Secretary, Research Advisory Committee, NUCSER
Member Secretary, Institute Ethics Committee, NUCSER
Member Secretary, Anti-Ragging Committee, NUCSER
Member Secretary, Institutional Committee Against Substance Abuse, NUCSER
Member Secretary, Students Grievance Cell, NUCSER
In charge, Institutional Public Relations Committee, NUCSER
Co-Founder-Consortium of Rare Genetic and Bone Marrow Disorders India Network@NITTEDU (N-CRG.BMD|IN).
Coordinator and Team Leader" a three weeks intensive training on cutting edge technologies in biomedical research at University of Miyazaki, Japan, Oct 5 -18, 2015, under Japan-Asia Youth Exchange program in Science (SAKURA exchange program in science) funded by JST, Govt. of Japan.
• Doctor of Philosophy (Medical Microbiology), Kasturba Medical College, 1985
• Master of Science (Microbiology), Kasturba Medical College, 1975
• International Jury Member of UNESCO for the International Life Science Research Award, 2013-2019.
• Research and Academic Excellence Award by Hindustan Group of Institutions, Hindustan University, 2017
• Sir. M. Visvesvaraya Award for excellence in research and lifetime contribution to Science and Technology, Govt. of Karnataka, 2014
• National Technology Development Award, Department of Biotechnology, Government of India, 2014
• Eminence in Virology Award, Amity University of Virology and Immunology, 2013
• Dr. T.S. Vasundhara Memorial Oration Award, Defense Food Research Laboratory, Mysore, 2012
• Dr. J.V. Bhat Endowment Oration Award, Manipal University, Manipal, 2012
• Fellow, National Academy of Agricultural Sciences, 2011 • TVR Pillay Foundation National award, 2008
• Rafi Ahmed Kidwai Award, Indian Council of Agricultural Research, 2007
• S. Swaminathan Award, Professional Fisheries Graduates Forum, India, 2005
• National Women Bio-scientist Lifetime achievement Award, Department of Biotechnology, Ministry of Science and Technology, India, 2003
• Vyas Memorial Award, Association of Microbiologists of India, 2002
• Outstanding Woman Scientist Award, Indian Council of Agricultural Research, 1998
• Laljee Godhoo Smarak Nidhi award, Association of Food Science and Technology, 1997
• Distinguished alumnus award, Kasturba Medical College, Manipal, 1990
• Certificate of appreciation, US Dept. of Agriculture for excellence in research, 1989
• Young Scientist award, Karnataka Association for Advancement of Science, 1986
• Scientific Advisor, International Foundation for Science, Sweden
• Member, National Scientific Advisory Council of DBT, Government of India
• Member, Programme Steering and Monitoring Committee (PSMC) under the Biotech Krishi Innovation Science Application Network (Biotech-KISAN)
• Advisor, Agricultural Scientists Recruitment Board (ICAR) ASRB for Recruitment of Scientists
• Rajesh, M.K., Muralikrishna, K.S., Nair, S.S., Kumar B.K., Subrahmanya, T.M., Sonu, K.P., Subaharan, K., Swetha, H., Keshava, P.T.S., Neeli, C., Karunasagar, I., Hebbar, K.B., Karun, A. (2020). Facile coconut inflorescence sap mediated synthesis of silver nanoparticles and its diverse antimicrobial and cytotoxic properties. Materials science & engineering: C. 111: 110834.
• Mohan Raj, J.R., Karunasagar, I. (2019) Phages amid antimicrobial resistance. Critical Reviews in Microbiology. 45:701-711.
• Rohit, A., Deekshit, V.K., Balaraj, M., Alandur, V.S., Abraham, G., Karunasagar, I., Karunasagar, I. (2019) CTX-M type extended-spectrum β-lactamase in Escherichia coli isolated from extra-intestinal infections in a tertiary care hospital in south India. Indian Journal of Medical Research. 149 (2):281-284
• Turner, L.M., Havenhand, J.N., Alsterberg, C., Turne,r A.D., Girisha, S.K., Rai, A., Venugopal, M.N, Karunasagar, I., Godhe, A. (2019) Toxic algae silence physiological responses to multiple climate drivers in a tropical marine food chain. Frontiers in Physiology. 10:373
• Anupama K. P, Chakraborty, A., Karunasagar, I., Karunasagar, I., Maiti., B. (2019) Loop-mediated isothermal amplification assay as a point-of-care diagnostic tool for Vibrio parahaemolyticus: Recent developments and improvements. Expert Review of Molecular Diagnostics 19(03): 229-239.
• D'Souza, C., Kumar, B.K., Kapinakadu, S., Shetty, R., Karunasagar, I., Karunasagar, I. (2018) PCR based evidence shows the presence of Vibrio vulnificus in wound infection cases in Mangaluru, India. International Journal of Infectious Diseases. 1:68:74-76.
• Yathisha, U.G., Bhat, I., Karunasagar, I., Mamatha, B.S. (2018) Antihypertensive activity of fish protein hydrolysates and its peptides. Critical Reviews in Food Science and Nutrition. 59:2363-2374
• Dubey, S., Avadhani, K., Mutalik, S., Sivadasan, S.M., Maiti, B., Girisha, S.K., Venugopal, M.N., Mutoloki, S., Evensen, O., Karunasagar, I., Munangandu, H.M. (2016) Edwardsiella tarda OmpA encapsulated in chitosan nanoparticles shows superior protection over inactivated whole cell vaccine in orally vaccinated fringed-lipped peninsula carp (Labeo fimbriatus). Vaccines 4(4): 40.
• Turner, L.M., Alsterberg, C., Turner, A.D., Girisha, S.K., Rai, A., Havenhand, J.N., Venugopal, M.N., Karunasagar, I., Godhe, A. (2016) Pathogenic marine microbes influence the effects of climate change on a commercially important tropical bivalve. Scientific Reports. 6:32413.
• Karunasagar, I., Karunasagar, I., Raghunath P. (2016); Editorial: Ecology, virulence and detection of pathogenic and pandemic Vibrio parahaemolyticus. Frontiers in Microbiology. 7:156.
• Multiple climate impacts as bottlenecks to the microbiome of the aquatic environment (Indo-Sweden-UK), funded by FORMAS, 2017-2020 [budget: 40 lakhs]
• Testing the potential of microalgae-bacteria consortium to manage pathogens in cultured shrimps (Indo-Sri Lanka), funded by Swedish Research Council, Sweden, 2017-2020 [Budget: 89 lakhs]
• Defence genes of tiger shrimp (Penaeus monodon) with respect to bacteria (Vibrio harveyi) and white spot virus (WSSV) infection, funded by DST-BELSPO, 2017-2020 [budget: 12.49 lakhs]
A plant biotechnologist by training, having 28 years of experience in academics and research. I have worked extensively on tissue culture, conservation, biodiversity and molecular markers in tree species and Pteridophytes. My team has screened several Pteridophytes for phytoremediation of heavy metals from contaminated soil and liquid systems. My current research interest is in vitro production of secondary metabolites of herbal medicinal plants.
Plant molecular Biology.
Genetic diversity and distribution studies of Pteridophytes.
Abiotic and heavy metal stress induced studies in plant systems.
In vitro propagation of trees and medicinal plants.
Bioremediation and phytoremediation of toxic pollutants.
Aranya Mitra awarded by the Karnataka State Forest Department, Mangalore during Vrukshotsava 2019, 2019.
Individual Personality for contribution towards Plantations and Greenery on occasion of World Environment Day 2019, by the Karnataka State Pollution Control Board, Mangalore, 2019
Certificate of merit for best paper, at the DST sponsored National Teachers Science Congress, Ahmedabad, 2018
Sofia Lecturing Research Award- 2017, Sofia University, Tokyo, Japan
Sahyadri Ecologist Award for best paper, International Conference on Conservation and Sustainable management of Ecologically sensitive regions in Western Ghats, Indian Institute of Science, Bangalore and Alva's College, Moodabidri, 2016.
Karnataka State Eligibility for Lectureship (KSET) certificate, 2015.
SS BIR Gold medal for outstanding work in Pteridology, 2014
INSA-COSTED Travel fellowship to attend International Pteridophyte symposium, Guildford, UK, 2001.
CSIR & Costed IBN Travel Grant to attend International Pteridophyte Symposium, Royal Botanic Gardens, Kew, UK, 1995.
In charge, Student welfare committee, NUCSER
In charge, Academic committee, NUCSER
Member secretary, Gender Equity Cell, Nitte DU
Member secretary, Nitte University Green Initiative Projects Nitte DU
Member secretary, Equal Opportunity Cell, Nitte DU
Member, Academic Council of Nitte Deemed to be University
Member, Board of Studies in Biological Sciences (UG & PG), Nitte DU
Establishment of Technology Enabling Centre (TEC), funded by DST, 2019-2020 [Budget 99.72 lakhs]
DNA barcoding of Ferns of South India for genetic diversity studies, funded by DST-SERB, 2017-2020.
Currently enrolled PhD students: 5
Completed and awarded PhD students: 5
Guided PG research project students: 102
Guided UG research project students: 4
Patent applied: 2
Over the past 12 years I have worked on development of many new diagnostic techniques for a bacterial, viral pathogen as well as a parasite affecting humans using my expertise on LAMP technique and characterization (identification and function) of cytokines under different stress/infection. At present my research area and interest focusses on development of rapid molecular detection techniques, development of transgenic zebrafish lines for human diseases, Human /animal parasitology, and Molecular Immunology.
Doctor of Philosophy (Applied Biochemistry and Bioscience), University of Miyazaki, Japan, 2007
Master of Science (Aquaculture), West Bengal University of Animal Sciences, Kolkata, 2003
Molecular detection techniques
Coordinator, Namaste Centre, Nitte DU
Coordinator, Healthy University Initiative, NUCSER
Member, Nitte Sakura Science Forum
Generation of transgenic zebrafish models for elucidating the molecular mechanisms of Mycobacterium infection, funded by NitteDU, 2019-2020 [Budget: 1.6 lakhs]
Screening of gene mutations that interferes with response to CCRT in esophageal cancer patients: AS-LAMP assays using cell free DNA, funded by NitteDU, 2019-2021 [Budget: 1.9 lakhs]
Japan-Asia Youth Exchange program in Science for undergraduates (SAKURA exchange program in science) coordinator, 2018
Japan-Asia Youth Exchange program in Science (SAKURA exchange program in science) awardee, 2016
Following Ph.D., Dr. Biswajit Maiti continued his research career at the College of Fisheries, Mangaluru. Later, he joined NUCSER as Assistant Professor in 2013. He has also worked as a visiting researcher in Food Microbiology at Obihiro University, Japan, during 2015 -2016. From the past decade, he has been working on the development of cutting-edge diagnostic methods for rapid detection microbial pathogens, deciphering outer membrane proteins based-antibiotic resistance of bacterial pathogens, and development of novel vaccines using biotechnological approaches. He has numbers of publications in scientific journals of repute, and book chapters to his credit, received research funds from various external agencies, and guiding students for their Ph.D., and postgraduate research dissertation.
Doctor of Philosophy (Bioscience), Mangalore University, 2012
Master of Science (Microbiology), Jiwaji University, 2006
Associate professor - Grade I, Nitte University Centre for science education and research, Mangaluru (2018- till date)
Assistant Professor, Nitte University Centre for science education and research, Mangaluru (2013- 2018)
Post-doctoral fellow (Food Microbiology), Obihiro University, Hokkaido, Japan (2015 - 2016)
Post-doctoral research associate, College of Fisheries, Mangaluru (2012 - 2013)
Development of diagnostic methods for the pathogenic bacteria.
Pathogenesis and antibiotic resistance mechanisms of bacteria.
Membrane proteins of Gram-negative bacteria.
Aquaculture and Marine Biotechnology.
Dr. (Mrs.) Gouri Ganguly Memorial Award for Young Scientist, Indian Science Congress, 2018.
Visiting researcher at Obihiro University, Japan, 2015
WFCC-MIRCEN-WDCM meeting on Microbial Resources Management and Utilization, IMCAS, Beijing, China, 2014
Young scientist award, Association of microbiologist of India, 2012
Short-term research fellowship, Nofima AS, Tromsø, Norway, 2010
TCDC Expert (laboratory management), FAO-UN, Dhaka, Bangladesh, 2010
Member, Board of Studies in Biological Sciences (UG & PG), Nitte DU
Member, Web Design Committee, Nitte DU
Member, Internal Quality Assurance Cell, NUCSER
Coordinator, Nitte News, NUCSER
Member, Information and Communication Technology Cell, NUCSER
Member, Institutional Committee Against Substance Abuse, NUCSER
Member, Institutional Library Committee, NUCSER
In-charge, Lab Resource Committee, NUCSER
Member, Public Relations Committee, NUCSER
Deciphering outer membrane protein-based resistance of bacteria to antibiotics and bacteriophage for effective control of multidrug-resistant Acinetobacter baumannii, funded by ICMR, 2020-2023 (Recommended) [Budget: 25.56 lakhs]
Biotechnological approaches for prevention and control of fish disease in aquaculture (BIOAQUA), funded by DST (Indo-Norway joint research project), 2019-2022 [Budget: 45.32 lakhs]
Understanding the role of membrane proteins in the multidrug-resistant clinical strain of Salmonella, funded by NitteDU, 2018-2020 [Budget: 1.75 lakhs]
Utility of cord blood neuronal biomarkers as a marker of Hypoxic Ischemic Encephalopathy, funded by NitteDU, 2019-2021 [Budget: 1.5 lakhs]
Testing the potential of microalga-bacteria consortium to manage pathogens in cultured shrimps, funded by Swedish Research Links, 2017-2020 [Budget: 89 lakhs]
Convener, Biotechnology in one health for pre-university college students sponsored by BRSI under the scheme Biotechnology popularization and skill development, 2019-2020.
Dr. Praveen Rai did PhD (Molecular Virology) from Karnataka Veterinary, Animal and Fisheries Sciences University, Bidar. He joined NUCSER in 2014. He has 24 research publications in highly rated journals of international standard, mostly related to molecular characterization of microbial pathogens. Currently, his research focuses on molecular characterization of Dengue and Rotaviruses, Antiviral Compounds, Host-Pathogen Interaction, Molecular Diagnostics, RNA Interference and Phage based biocontrol technologies.
Master of Science (Microbiology), Karnataka Veterinary, Animal and Fisheries Sciences University, 2008
Doctor of Philosophy (Microbiology), Karnataka Veterinary, Animal and Fisheries Sciences University, 2013
Associate Professor (G-I), Nitte University Centre for Science Education and Research, Mangaluru (Nov 2018–To date)
Assistant Professor, Nitte University Centre for Science Education and Research, Mangaluru (Aug 2014–Oct 2018)
Epidemiology and molecular characterization of human and animal viruses
Phage based biocontrol technologies
Young Scientist Award, DST-SERB, Gov. of India, 2015.
SAKURA science award, University of Miyazaki, Japan, 2015.
Dr. C.V Kulakarni Award for the Best PhD research, 2013.
Dr. N. R Menon Award for the Best Indian M.Sc. Thesis, 2009.
Dr. Jalihal Endowment Award for the All India best Master's Degree Research in Fisheries, 2008-2009.
Institutional Research Coordinator, NUCSER
Coordinator, NUelearn 2020, NUCSER
Member Secretary, Research Cell, NUCSER
Member Secretary, Institutional Placement and Career Guidance Cell, NUCSER
Subject Expert, Scientific Committee, Nitte DU
Member, Institutional Ethical Committee, NUINS
Member, Audit teams, Institutional Biosafety Committee (IBSC), Nitte DU
Member, Sub-Committee of the Board of Research Studies, Nitte DU
Member, Institutional Committee Against Substance Abuse, NUCSER
Member, Institutional Academic committee, NUCSER
Member, Hostel Committee, NUCSER
Member, Institutional Library committee, NUCSER
Dr. Deekshit completed his PhD (Microbiology) from Manipal University and had been worked as a research associate at UNESCO MIRCEN for Marine Biotechnology (KVAFSU), Mangalore. He did his short-term post-doc at University College Dublin, Ireland in the year 2018. His research focus includes molecular characterization of nontyphoidal Salmonella with special consideration to their antibiotic resistance mechanism which led to the detection of class 1 integrons in Salmonella Weltevreden and silent antibiotic resistance genes in some non-typhoidal isolates of Salmonella. Further, he developed a PCR for the simultaneous detection of Salmonella Pathogenicity Island 2 and its antibiotic resistance genes. He has also developed a Miss Match mutation PCR assay for the detection of QRDR mutation in fluoroquinolone resistant E. coli. His research interest includes identifying the characteristics of multidrug resistant gut pathogens in simulated gut condition as well as determining the anticancer ability non-typhoidal Salmonella in vitro.
Master of Fisheries Microbiology (M.FSc), KVAFSU, 2009
Doctor of Philosophy (Microbiology), Manipal university, 2014
Assistant Professor G-II, Nitte University Centre for Science Education and Research (2018- till date)
Assistant Professor G-I, Nitte University Center for Science Education and Research (2014-2018)
Research Associate, KVAFSU (2012-2014)
Infectious Disease Biology (Bacteriology)
Molecular Biology & Biotechnology
ITS-DST SERB Travel grant to attend IMED-2018, Vienna
The diligent employee of year award (NUCSER), 2017
EMBO short term Fellowship, University College Dublin, 2018
DST-SERB Early Career Research Award, 2017
Sakura Science Award, Miyazaki, Japan, 2015
College of Fisheries Alumni Association (COFAA) certificate of appreciation for academic excellence for the year, 2007
University merit scholarship by KVAFSU, Bidar, during post graduate studies (2007-2009)
University merit scholarship by KVAFSU, Bidar, during undergraduate studies (2003-2007)
Member Coordinator, IQAC & NAAC, NUCSER
Member, Antiaging Committee, NUCSER
Member, Institutional committee against sexual harassment, NUCSER
Member, Information and Communication Technology Cell, NUCSER
In-charge, Student Welfare committee, NUCSER
Coordinator, NUeLearn 2020-21, NUCSER
Member, Institutional COVID-19 task force, NUCSER
Decoding the traits of drug resistance: Studying the genetic factors contributing to the survivability and adaptability of gut pathogens in antibiotic rich environment, funded by DST-SERB, 2018-2021 [Budget: 34.35 Lakhs].
Investigating antimicrobial efficacy of NANOBIOTICS against multidrug resistant gut pathogens, funded by ICMR, 2020-2023 [Budget: 47 lakhs] (Recommended).
Effect of bile on the invasion and replication of drug resistant gut pathogens in Caco-2 cell line, funded by NitteDU, 2019-2021 [Budget: 1.9 Lakhs].
Deciphering outer membrane protein-based resistance of bacteria to antibiotics and bacteriophage for effective control of multidrug-resistant Acinetobacter baumannii, funded by ICMR, 2020-2023 [Budget: 25.56 lakhs] (Recommended).
Combating cancer through alternative approaches: Investigating the antitumor properties of non-typhoidal Salmonella in transgenic zebrafish cancer models, funded by ICMR, 2020-2023 [Budget: 52 lakhs] (Recommended).
Generation of transgenic zebrafish models for elucidating the molecular mechanism of Mycobacterium infection, funded by NitteDU, 2018-2020 [Budget: 1.6 Lakhs].
Quantification of thiamine levels and analysis of thiamine transporter gene in suspected Shoshin beriberi cases affecting a restricted population of Coastal Karnataka, funded by NitteDU, 2019-2021 [Budget:1.5 Lakhs]
Abstracts in national/ international conference: 11
Nucleotide sequence submissions to NCBI GenBank: 35
Expressed sequence tag sequence submissions: 3175
Bacterial whole genome sequence submission:06
Invited Talks /Oral Presentation (National/International): 03
National / International workshops / conferences / symposium attended: 32
Dr. Krishna Kumar Ballamoole is a molecular microbiologist, obtained Ph.D. (Microbiology) from Manipal University. His research focuses on the identification of virulence factors from pathogenic vibrios and elucidation of their activities to gain insight into their molecular pathogenesis. His research work combines state-of-the-art microbiology, molecular biology and next generation sequencing strategies to shed light on bacterial pathogenesis mechanism. In addition to pursuing the main research interest, he is s also involved developing monoclonal antibody and nucleic acid based rapid diagnostics for the detection of food borne pathogens.
Doctor of Philosophy (Microbiology), Manipal University, Manipal, 2014
Master of Science (Microbiology), Karnataka Veterinary, Animal and Fisheries Sciences University , 2009
Assistant Professor - Grade II, Nitte University Center for Science Education and Research, Mangaluru (2018-till date)
Assistant Professor, Nitte University Center for Science Education and Research, Mangaluru (2014- 2018)
Research Fellow, KVAFSU (2012-2014)
Member, Institutional Academic Committee, NUCSER
Member, Institutional Library Committee, NUCSER
Member, NSS Advisory Committee, NUCSER
Coordinator, NueLearn 2020-21, NUCSER
Anurag Sharm is working as Assistant Professor at NUCSER, Nitte University. During his Ph.D. he studied the stress response of endosulfan on D. melanogaster, a non-target organism, at sub-organismal as well as organismal level. Further, his studies also highlight the potential of D. melanogaster as an alternative animal model for in-vivo assessment of environmental chemical mediated toxicity, which might have relevance to higher organisms. Later, he joined CNRS-Centre de Biologie du Développement, Toulouse, France as a postdoctoral researcher and worked on deciphering the function of the Drosophila hematopoietic niche to maintain blood cell homeostasis. Presently, he is engaged in the following areas-a) Development of an in vivo Drosophila model to study toxicant/radiation induced hematopoietic perturbations and b) Host-Microbe interaction and environmental toxicants.
Doctor of Philosophy (Cellular and Molecular toxicology), CSIR-IITR Lucknow and Jamia Hamdard, 2012
Master of Science (Biotechnology), Jiwaji University, 2005
Assistant Professor, Nitte Centre for science education and research, Mangaluru (2016 – till date)
Postdoctoral Fellow (Developmental Biology), Centre de Biologie du Développement (CBD), Toulouse, France (2012 - 2016)
Cellular and Molecular toxicology
Cellular immune response
Cellular and molecular stress response
DST-SERB Young scientist start-up grant award, 2017
Japan-Asia Youth Exchange program in Science (SAKURA exchange) awardee, 2018
Member, Lab Resource Committee, NUCSER
Member Secretary, Institutional committee against sexual harassment, NUCSER
Member, Institutional committee against substance abuse, NUCSER
D'Souza, L.C., Mishra, S., Chakraborty, A., Shekher, A., Sharma, A.,* Gupta, .SC.* (2020) Oxidative stress and cancer development: Are non-coding RNAs the missing links? Antioxidants & Redox Signaling [Epub ahead of print].
Sharma A, D'Souza C, Rai V, Gupta SC. (2019) Evaluation of Safety and Efficacy of Nutraceuticals Using Drosophila as an in Vivo Tool. In: Nutraceuticals in Veterinary Medicine. Gupta R, Srivastava A, Lall R. (eds). Springer, Cham. ISBN 978-3-030-04624- 8.
Louradour, I., Sharma, A., Morin-Poulard, I., Letourneau, M., Vincent, A., Vanzo, N., Crozatier, M. (2017). Reactive oxygen species-dependent Toll/NF-κB activation in the Drosophila hematopoietic niche confers resistance to wasp parasitism. Elife 6:e25496. doi: 10.7554/eLife.25496.
Morin-Poulard, I., Sharma, A., Louradour, I., Vanzo, N., Vincent, A., Crozatier, M. (2016). Vascular control of the Drosophila hematopoietic niche: role of Slit/Robo signaling. Nature Communications 7:11634.
Sharma, A., Mishra, M., Shukla, A.K., Kumar, R., Abdin, M.Z., Chowdhuri, D.K. (2012). Organochlorine pesticide, endosulfan induced cellular and organismal response in Drosophila melanogaster. Journal of Hazardous Materials 221-222, 275-287.
Sharma, A., Mishra, M., Ravi Ram, K., Kumar, R., Abdin, M.Z., Chowdhuri, D.K. (2011). Transcriptome analysis provides insights for understanding the adverse effects of endosulfan in Drosophila melanogaster. Chemosphere 82: 370-376.
Sharma, A., Shukla, A.K., Mishra, M., Chowdhuri, D.K. (2011). Validation and application of Drosophila melanogaster as an in vivo model for the detection of double strand breaks by neutral Comet assay. Mutation Research/ Genetic Toxicology and Environmental Mutagenesis 721: 142-146.
All Publications: Google Scholar-
Decoding the molecular mechanism associated with ionizing radiation induced hematopoietic malignancy using Drosophila model system, funded by ICMR (Recommended), 2020-2022.
Deciphering the molecular mechanisms involved in hematopoietic perturbation induced by environmental chemical(s) using Drosophila as an animal model, funded by DST-SERB, 2017-2020 [Budget: 44.29 lakhs]
Elucidating the host-microbiome association in cadmium and/ nonyphenol exposed Drosophila melanogaster, funded by NitteDU, 2019-2021 [Bugget:1.9 lakhs]
Niche cues for stress hematopoiesis: insights from Drosophila, funded by NitteDU, 2019-2021 [3.0 lakhs]
With more than 15 years of experience in research and teaching, she has attended several conferences and been resource person at National and International level. Her latest visit to the U.S.A where she was invited as speaker to present a research paper on Zika virus at the First International Conference on Zika Virus 2017 held at Washington D.C, 2017. Her major research areas include Parasitology with special interest in Malaria in the city of Mangaluru where drug resistance is beginning to appear. She is presently working in the division of Bioinformatics and Computational genomics with increased surveillance and research on various viruses spreading across the globe.
Assistant Professor, Nitte University Center for Science Education and Research, Mangaluru (2013- till date)
Project Assistant, College of Fisheries, Mangaluru (2006-2013)
Molecular characterization of malarial plasmodium
Malaria and Antimicrobial Resistance
Sequencing and bioinformatics
Member, Board of Studies in Biological Sciences (UG and PG), Nitte DU
Member, Lab Vigilance Committee, NUCSER
Program Officer-NSS, NUCSER
Currently guiding Ph.D. student, working on the malaria problem in south-west India
Dr. Ramya Harsha is an Assistant Professor at NUCSER. She has obtained her Ph.D. degree from Department of Microbiology, University of Mysore in the year 2012. She joined NUCSER in 2013. Her research interests include virulence in bacterial pathogens, quorum sensing and isolation of anti-quorum sensing molecules from phytal sources and attenuation of quorum sensing in bacteria. She has secured second rank in MSc Microbiology from University of Mysore.
Doctor of Philosophy (Microbiology), University of Mysore, 2012
Master of Science (Microbiology), University of Mysore, 2000
Assistant Professor, Nitte Centre for science education and research, Mangaluru (2013 – till date)
Guest faculty, Dept. of Microbiology, University of Mysore (2006 - 2011)
Infectious Disease Biology (Bacteriology)
Virulence mechanisms of pathogens
Bacterial quorum sensing
Isolation and identification of anti-quorum sensing molecules
Sakura Science Fellowship administered by Japan Science & Technology, 2018
Member, Alumni coordinator, NUCSER
Coordinator AISHE, NUCSER
Coordinator, NUeLearn, NUCSER
In charge of Lab vigilance committee, NUCSER
In charge of Hostel committee, NUCSER
Member, I-CASA, NUCSER
Member, Internal Quality Assurance Cell, NUCSER
Member, COVID-19 task force, NUCSER
Expertise in the area of molecular biology, genetic engineering and RNAi approach. Developed recombinant protein vaccines, dsRNA and antisense constructs against viral infection in invertebrate. Developed molecular and antibody based diagnostic kit for the detection of mastitis pathogens. Involved in the development of phage therapy to combat antibiotic resistant food pathogens.
Doctor of Philosophy (Microbiology), Karnataka Veterinary Animal and Fisheries Science University, 2014
Master of Science (Microbiology), Karnataka Veterinary Animal and Fisheries Science University, 2010
Food microbiology and biotechnology
University gold medal award by Karnataka Veterinary Animal and Fisheries Science University, 2015
Poster presentation award by Indian association of veterinary microbiologist, immunologist and specialist in infectious diseases, 2011
Late M.N. Kulkarni Memorial award by Indian association of veterinary microbiologist, immunologist and specialist in infectious diseases, 2011
University Merit Scholarship during the year, 2008-10
Member, Board of Studies in Biological Sciences(UG & PG), Nitte DU
Member, Lab Infrastructure committee, NUCSER
Santhosh, S.K., Deekshit, V.K., Vittal, R., Akhila, D.S., Mundanda, D.M., Mohan Raj, J.R., Chakraborty, A., Karunasagar, I. (2019) Phenotypic & genotypic study of antimicrobial profile of bacteria isolates from environmental samples. Indian Journal of Medical Research 149(2):232-239.
Das, A., Vittal, R., Mohan Raj, J.R., Akhila, D.S. (2019) Phenotypic and genotypic characterization on of Listeria Species Isolated from Ready-to-Eat Dairy Products. Indian Journal of Comparative Microbiology , Immunology and Infectious Diseases http://dx.doi.org/ 10.5958/0974- 0147.2019.0000 2.3
Banu, S., Santhosh, K.S., Akhila, D.S., Dechamma, M.M., Mathew, M.S., Prarthana, A. (2018) Molecular characterization of antimicrobial drug resistant Escherichia coli isolated from the environment at Dakshina Kannada, Karnataka. Journal of Pure and Applied Microbiology 12(4):1-7.
Akhila, D.S., Madhu K M., Rai, P., Condon, K., Owens, L., Karunasagar, I. (2015) Antisense RNA mediated protection from white spot syndrome virus (WSSV) infection in Pacific white shrimp Litopenaeus vannamei. Aquaculture 435: 306-309.
Akhila, D.S., Rai. P., Mani, M.K., Kumar, K.B., Karunasagar. I., Karunasagar, I. (2015). Protection of Litopenaeus vannamei against white spot syndrome virus using bacterially expressed recombinant envelope proteins VP39 and VP28. Israeli journal of aquaculture 67:1-11
All Publications: Google scholar-
Conference publications- 7
Novel RNAi therapeutic approach to combat multidrug resistance in Klebsiella species, funded by NitteDU, 2018-2020 [Budget: 1.80 lakhs]
'Klebsiella pneumoniae infections and antimicrobial drug resistance' chapter is published in the book entitled as Model organism for microbial pathogenesis, biofilm formation and antimicrobial discovery (2020), ISBN 978-981-15-1694-8.
Dr. Mamatha BS completed her Ph.D. from CFTRI, Mysore. Pursued teaching as my career and joined St. Aloysius College (Autonomous), Mangalore from 2014- 2017. Later, she joined NUCSER in 2017. She have 18 research articles and external reseach projects to her credits. Her research interest lies in two areas of food science, the bioavailability of lutein (xanthophyll carotenoid) in mice model and antihypertensive peptides from fish protein hydrolysates.
Doctor of Philosophy (Nutritional Biochemistry), Central Food Technological Research Center (CFTRI), University of Mysore, Mysore, 2013
Master of science (Food Science and Nutrition), University of Mysore, 2002
Nutrition Society of India (NSI) prize for the Best Oral Presentation during, 2019
Certificate of appreciation awarded in recognition of achievement/ dedicated and valuable service towards enhancing quality of education in "Sambhrama" 2015 and 2017, St. Aloysius college, Mangalore
Senior Research fellowship by the Indian Council of Medical Research (ICMR), 2007.
Awarded First prize for the poster presented, ICFOST-2005, NIMHANS, Bangalore.
Member, Hostel committee, NUCSER
Member, Academic committee, NUCSER
In-charge, Women cell, NUCSER
Dr. Sudarshan Kini received his Ph.D. degree in design and development of nanobiomaterials for anticancer drug delivery applications. Later he obtained his postdoctoral experience in Nanodiagnostics from Manipal Academy of Higher Education during 2015-2018. Presently he is working on the development of 3D animal cell culture and Nanosensors.
Doctor of Philosophy (Nanobiomaterials), Indian Institute of Technology Bombay, 2015
Master of Science (Biochemistry), Bharathiar University, 2008
Nanobiomaterials and Nanodiagnostics
Cancer Cell Biology
Best Paper award at International conference on Recent Advances in Materials Science and Biophysics at Mangalore, 2018.
Best poster in the International symposium on Nanotechnology and Cancer Theranostics (ISNACT-2015) at IIT Bombay, 2015
GATE qualified with 98.27 percentiles, All India rank 226, score 476.
Alumni coordinator for NUCSER
Member, Lab resource committee, NUCSER
Hostel committee, NUCSER
Coordinator, Electoral Literacy Club, NUCSER
Member, Youth Red Cross committee, Nitte DU
Poojari, R., Sawant, A.V., Kini, S., Srivastava, R., Panda, D. (2020) Antihepatoma activity of multifunctional polymeric nanoparticles via inhibition of microtubules and tyrosine kinase. Nanomedicine (London, England) 15(4), 381-396.
Hegde, S., Anchan, B., Kamath, S. U., Kini, S., De, S., Patil, A. (2019) Design and development of ZnO based device for biosensing applications. In A. Asundi, & Q. Kemao (Eds.), Seventh International Conference on Optical and Photonic Engineering, icOPEN 2019 [112052A] (Proceedings of SPIE - The International Society for Optical Engineering; Vol. 11205). SPIE. doi: 10.1117/12.2551081.
Kini, S., Kulkarni, S.D., Ganiga, V., Nagarakshit, T.K., Chidangil, S. (2019) Dual functionalized, stable and water dispersible CdTe quantum dots: Facile, one-pot aqueous synthesis, optical tuning and energy transfer applications. Materials Research Bulletin 110:57-66.
Kini, S., Ganiga, V., Kulkarni, S.D., Chidangil, S., George, S.D. (2018) Sensitive detection of mercury using the fluorescence resonance energy transfer between CdTe/CdS quantum dots and Rhodamine 6G. Journal of Nanoparticle Research 20:232.
Thakur, R., Kini, S., Kurkalang, S., Banerjee, A., Chatterjee, P., Chanda, A., Chatterjee, A., Panda, D., Mukherjee, A. K. (2016) Mechanism of apoptosis induction in human breast cancer MCF-7 cell by Ruviprase, a small peptide from Daboia russelii russelii venom. Chemico-biological interactions 258, 297-304.
Poojari, R., Kini, S., Srivastava, R., Panda, D. (2016) Intracellular interactions of electrostatically mediated layer-by-layer assembled polyelectrolytes based sorafenib nanoparticles in oral cancer cells. Colloids Surfaces B Biointerfaces 143:131-8.
All Publications: Google Scholar- https://scholar.google.com/citations?user=ixAqu2MAAAAJ&hl=en
A novel rapid sensitive fluorescent resonance energy transfer technique for selective detection and quantification of methicillin resistant Staphylococcus aureus, funded by DST-SERB-Early Career Research, 2019-2021 [Budget: 36.14 lakhs]
Nano-formulation of lutein to improve bioavailability in prevention of Age-Related Macular Degeneration, funded by ICMR, 2019-2021 [Budget: 24.28 lakhs]
In the current scenario where antibiotics no longer work, the need for alternative strategies have looked at phage therapy and I have been actively involved in research on phage-based therapeutics not only for human therapeutic use but also biocontrol in foods for more than 10 years.
Phage therapy and phage biology
Institutional Grievance Redressal officer, NUCSER
Member, Lab infrastructure committee, NUCSER
Member, Women's Cell, NUCSER
Mohan, Raj, J.R., Karunasagar, I. (2019) Phages amid antimicrobial resistance. Critical Reviews in Microbiology. 45:701-711.
Mohan Raj, J.R., Vittal, R., Santhosh, K.S., Deekshit, V.K., Chakraborty, A., Karunasagar, I. (2019) Presence and mobility of antimicrobial resistance in Gram negative bacteria from the environment of coastal Karnataka, India. Indian Journal of Medical Research 149;290-294
Shivakumaraswamy, S.K., Deekshit, V.K., Vittal, R., Akhila, D.S., Mundanda, D.M., Mohan Raj, J.R., Chakraborty, A., Karunasagar, I. (2019) Phenotypic & genotypic study of antimicrobial profile of bacteria isolates from environmental samples. Indian Journal of Medical Research.149:232-239
Mohan Raj, J.R., Vittal, R., Huilgol, P., Bhat, U., Karunasaga,r I. (2018) T4‐like Escherichia coli Phages from the Environment Carry bla CTX‐M. Letters in Applied Microbiology 67(1):9-14
Alva, P.P., Raj J.M., Karunasagar, I., Premanath, R. (2018). Environmental and clinical Pseudomonas aeruginosa isolates with pooled presence of exo S, exo U, exo T and exo Y genes. Journal of Pure and Applied Microbiology 12(3):1119-1125.
Roshini Juliet., Karunasagar, I. (2017) Prevalence of blaCTX-M is coliphages isolated from sewage. Advanced Science Letters 23:3; 1869-1871.
Kumar, B.K., Deekshit, V.K., Raj, J.R., Rai, P., Shivanagowda, B.M., Karunasagar, I, Karunasagar, I. (2014) Diversity of Vibrio parahaemolyticus associated with disease outbreak among cultured Litopenaeus vannamei (Pacific white shrimp) in India. Aquaculture 433:247-251.
Junjappa, R.P., Desai, S.N., Roy, P., Narasimhaswamy, N., Raj, J.R., Durgaiah, M., Vipra, A., Bhat, U.R., Satyanarayana, S.K., Shankara, N., Basingi, S.M., Bhat, J.J., Hariharan, S., Sriram, B., Padmanabhan, S. (2013) Efficacy of anti-staphylococcal protein P128 for the treatment of canine pyoderma: potential applications. Veterinary Research Communication 37:217-28
Vipra, A.A., Desai, S.N., Roy, P., Patil, R., Juliet, M.R., Narasimhaswamy, N., Paul, V.D., Chikkamadaiah, R., Sriram, B. (2012) Antistaphylococcal activity of bacteriophage derived chimeric protein P128. BMC Microbiology 12: 41.
All publications: Google Scholar- https://scholar.google.com/citations?user=6Mx7uQUAAAAJ&hl=en
Biocontrol of biofilm forming bacteria isolated from diabetic ulcers using phage, funded by NitteDU, 2018-2020 [Budget 1.7 lakhs]
Utility of polymerase chain reaction in the identification of dermatophytes in recalcitrant dermatophytosis, funded by NitteDU, 2018-2020 [Budget 1.2 lakhs]
Evaluation of resistant genes in recalcitrant Dermatophytosis - A PCR based study, funded by NitteDU, 2018-2020 [Budget 1.5 lakhs]
I am presently working as a Senior Lecturer in NUCSER, have 6 years of teaching experience and am pursuing my Ph.D. in Biological Science stream. In addition, my expertise is in analysis of water quality parameters, microbiological techniques (soil and water), molecular techniques and toxicological studies (acute and chronic toxicity tests). I have been guiding the PG students as a guide and a Co-guide. I am also involved in analyzing external samples of food and water, and also involved in providing training to the personnel form different parts of the country. I have few GenBank submission in my name.
Master of Science (Ecology & Environment), KVAFSU, 2009
Senior Lecturer, Nitte University Centre for science education and research, Mangaluru, (2018-till date)
Lecturer, Nitte University Centre for science education and research, Mangaluru (2014 – 2018 )
Senior Research Fellow, Department of Microbiology, KVAFSU (2014 to 2014)
Senior Research Fellow, Department of Ecology & Environment, KVAFSU, (2008 to 2010)
Japan- Asia Youth Exchange Program in Science (SAKURA exchange), awardee 2017
Training workshop on Antimicrobial Susceptibility Testing at PGIMER, Chandigarh, 2016
Participant, Responsible Conduct of Science Research sponsored by US National Academy of Science, 2015
Member, Student welfare committee, NUCSER
Das, A., Vittal, R., Raj, J.R., Akhila, D.S. (2019) Phenotypic and genotypic characterization of Listeria species isolated from ready-to-eat dairy products. Indian Journal of Comparative Microbiology, Immunology and Infectious Diseases 40(1):11-4.
Shivakumaraswamy, S.K., Deekshit, V.K., Vittal, R., Akhila, D.S., Mundanda, D.M., Raj, J.R., Chakraborty, A., Karunasagar, I. (2019) Phenotypic & genotypic study of antimicrobial profile of bacteria isolates from environmental samples. Indian Journal of Medical Research 149(2):232.
Shetty, S.S., Deekshit, V.K., Jazeela, K., Vittal, R., Rohit, A., Chakraborty, A., Karunasagar, I. (2019) Plasmid-mediated fluoroquinolone resistance associated with extra-intestinal Escherichia coli isolates from hospital samples. Indian Journal of Medical Research 149(2):192.
Raj, J.R., Vittal, R., Shivakumaraswamy, S.K., Deekshit, V.K., Chakraborty, A., Karunasagar, I. (2019) Presence & mobility of antimicrobial resistance in Gram-negative bacteria from environmental samples in coastal Karnataka, India. Indian Journal of Medical Research 149(2):290.
Raj, J.R., Vittal, R., Shivakumaraswamy, S.K., Deekshit, V.K., Karunasagar. I. (2017) Comparison of antimicrobial resistance in Gram negative bacteria isolated from effluents in coastal districts of Karnataka, India. Nitte University Journal of Health Sciences 7 (4): 2249-7110.
Mohan Raj, J.R., Vittal, R., Huilgol, P., Bhat, U., Karunasagar, I. (2018) T4‐like Escherichia coli Phages from the Environment Carry bla CTX‐M. Letters in applied microbiology 67:9-14.
All Publications: Google scholar-
Secured Ph.D. in Biotechnology from CUSAT, and worked as Research Associate at IIT, New Delhi, Delhi University, Centre for Cellular & Molecular Biology, Hyderabad, and College of Fisheries, Mangalore. Received an International Fellowship for Short-term Postdoctoral work at Research Institutes for Fisheries & Aquaculture, Hungary. After, worked as Research Associate at Central Institute of Fisheries Education, Mumbai and NUCSER. Joined as Scientist (G-I) in 2019 at NUCSER.
Scientist - Grade I, Nitte University Center for Science Education and Research, Mangaluru (2019-till date)
Research Associate, NUCSER, Mangalore (2017-2019)
Research Associate, Central Institute of Fisheries Education, Mumbai (2015-2016)
Post-doctoral Fellow, Research Institutes for Fisheries & Aquaculture, HUNGARY (2014-2015)
Research Associate, College of Fisheries, Mangalore (2013-2014)
Research Associate, Centre for Cellular & Molecular Biology, Hyderabad (2009-2012)
Bioactive compounds; AMPs
Member, Students Welfare Committee, NUCSER
Sports Advisor, NUCSER
Member Secretary, Youth Red Cross, Nitte DU
Member, Lab Equipment Committee, NUCSER
After competing my Ph.D., I have worked as Research associate and joined NUCSER as Scientist (G-I) in 2019. My research interest includes Infectious Disease Biology (Bacteriology), Antimicrobial Resistance, Food Microbiology and Biopolymers.
Member, Student Welfare Committee, NUCSER
The focus of my research is to understand the functioning of disordered and hybrid proteins, with respect to age associated diseases like neurodegeneration and cancer. A parallel interest is to develop amyloid based bio-nanocomposites for diverse applications. During my postdoc at Erasmus Medical Center, Rotterdam and PhD, I gained expertise in protein conformation studies using atomic force microscopy by single molecule imaging and analysis of DNA repair proteins (BRCA2-RAD51), study of polymorphism in self-assembled amyloids (α-synuclein) and functionalization of amyloids with gold nanoparticles (conductive nanowires). I joined NUCSER in 2020.
Doctor of Philosophy (Nanobiophysics), University of Twente, The Netherlands, 2016
Master of Science (Human Genomics), Panjab University, India, 2007
Best debater on "Impact of Nanotechnology on Society", 2014
Immunology foundation fellowship, 2009
EMBO travel award, 2009
UGC-NET lectureship, 2007
Gold medal Panjab University, 2007
Member: Student Welfare Committee, NUCSER
Coordinator, Departmental Journal Club and Work-Discussions, NUCSER
Arshdeep Sidhu, Małgorzata Grosbart, Humberto Sánchez, Bram Verhagen, Nick L L van der Zon, Dejan Ristić, Sarah E van Rossum-Fikkert, Claire Wyman (2020) Conformational flexibility and oligomerization of BRCA2 regions induced by RAD51 interaction. Nucleic Acids Research. (In press) https://doi.org/10.1093/nar/gkaa648 [IF: 11.501]
Sidhu, A*., Vaneyck, J., Blum, C., Segers-Nolten, I., Subramaniam, V. (2018) Polymorph-specific distribution of binding sites determines thioflavin-T fluorescence intensity in Î±-synuclein fibrils. Amyloid 25(3), 189-196.
Sidhu, A., Ristic, D., SÃ¡nchez, H., Wyman, C. (2018) The recombination mediator BRCA2: Architectural plasticity of recombination intermediates revealed by single-molecule imaging (SFM/TIRF). Methods in Enzymology 600: 347-374.
Sidhu, A., Segers-Nolten, I., Raussens, V., Claessens, M. M., Subramaniam, V. (2017). Distinct Mechanisms Determine Î±-Synuclein Fibril Morphology during Growth and Maturation. ACS chemical neuroscience 8(3), 538-547.
Sidhu, A., Segers-Nolten, I., Subramaniam, V. (2016). Conformational Compatibility Is Essential for Heterologous Aggregation of Î±-Synuclein. ACS chemical neuroscience 7(6), 719-727.
Raiss, C.C., Braun, T.S., Konings, I.B., Grabmayr, H., Hassink, G.C., Sidhu, A., le Feber, J., Bausch, A.R., Jansen, C., Subramaniam, V., Claessens, M.M. (2016). Functionally different Î±-synuclein inclusions yield insight into Parkinson's disease pathology. Scientific reports 6, 23116 .
Sidhu, A., Segers-Nolten, I., Subramaniam, V. (2014). Solution conditions define morphological homogeneity of Î±-synuclein fibrils. Biochimica et biophysica acta 1844(12), 2127-2134.
Sidhu, A., Surolia, A., Robertson, A. D., Sundd, M. (2011). A hydrogen bond regulates slow motions in ubiquitin by modulating a Î²-turn flip. Journal of molecular biology 411(5), 1037-1048.
Sidhu, A., Sundd, M. (2009) Protein biotechnology and its applications. Biotechnology applications, ed. C.S.K Mishra.; 213-230.
Conference publications- 01
Invited Talks- 05