Overview
ADMISSION TO DBT SPONSORED MSc IN MARINE BIOTECHNOLOGY
The focus in Marine Biotechnology program is to provide appropriate theoretical knowledge and laboratory skills for the development of various biotechnological tools and technologies in marine sciences and to implement the needs of the economy through marine entrepreneurship, study of marine environmental systems and fisheries, development of marine biotechnological processes. The program provides training in basic and advanced skills meant to empower youth to develop the sustainable strategy of harnessing the marine environment for food, medicines and other resources. This postgraduate program is sponsored by the Ministry of Science & Technology, Department of Biotechnology (DBT), Government of India. Students are selected through a National Level Graduate Aptitude Test-Biotechnology (GAT-B) and the selected ones are awarded with a fellowship by DBT, Govt. of India. However, students who do not appear for GAT-B examination can enrol under the non-DBT category with the existing tuition fee of the university but without a fellowship.
Faculty
Prof. (Dr.) ANIRBAN CHAKRABORTY
- Designation Director, Dean-Faculty of Biological Sciences
- Email anirban@nitte.edu.in
- Contact No. 91-824-2204292
- Joining date 01-08-2014
My specific area of research is to understand the role of ribosomes in bone marrow failure syndromes and cancer. Other areas of research include developing non-invasive and alternative DNA-based molecular tools for detection of specific mutations in cancer, developing transgenic zebrafish as cancer models and screening of natural antic-cancer compounds in zebrafish using HTS technology.
- Doctor of Philosophy (Molecular Biology), United Graduate School of Agricultural Sciences, Kagoshima University, University of Miyazaki, Japan, 2006
- Master of Science (Microbiology), UAS, Bangalore, 1999
- Founder- Consortium of Rare Genetic and Bone Marrow Disorders India Network@NITTEDU (N-CRG.BMD|IN)
- Founder- The Cancer Gene Database@NitteDU(N-TCAG)
- Dean- Faculty of Biological Sciences- Nitte DU (Oct 2020 - To date)
- Director, Centre for Science Education and Research (Oct 2020 - To date)
- Deputy Director, Centre for Science Education and Research (Oct 2017 – Sep 2020)
- Professor, Centre for Science Education and Research (Jan 2017- to date)
- Associate Professor, Centre for Science Education and Research (Aug 2014- Dec 2016)
- Senior Research Associate, Laboratoire de Biologie Moleculaire Eucaryote (LBME), UMR CNRS 5099, Toulouse, France (June 2012- June 2014)
- Postdoctoral Fellow, Frontier Science Research Center, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan (May 2006- March 2012)
- Zebrafish Biology and its applications in Genomics, Pharmacology, Toxicology, Marine Biotechnology
- Aquatic Animal Health Management: Probiotics and Nanovaccines
- Modeling of Rare Genetic Disorder and Cancer in Zebrafish
- Novel Non-invasive Molecular Techniques in Cancer Management
- Zebrafish-based Drug Screening and Discovery
- Best Researcher of NUCSER by Nitte (Deemed to be University), 2020
- Best Researcher of Nitte (Deemed to be University) and Best Researcher of NUCSER by Nitte (Deemed to be University), 2018
- Early Career Research Award by Dept. of Science and Technology, Science and Engineering Board (DST-SERB), Govt. of India, 2016.
- Japan-Asia Youth Exchange program in Science (SAKURA exchange program in science) coordinator, 2015
- The Strategic Priority Research Award by the University of Miyazaki, Faculty of Medicine, Japan, 2011
- Post-doctoral Fellowship for Foreign Researchers by the Japanese Society for Promotion of Science (JSPS), 2006-2008
- Dr. V.G. Jhingran Award for the Best Overseas Indian PhD Thesis Award for the year 2006 by Professional Fisheries Graduates Forum, Mumbai, India
- Monbukagakusho (MEXT) fellowship for PhD by the Government of Japan, 2002-2006
- Senior Research Fellowship by Indian Council of Agricultural Research, India, 2002-2003
- National Eligibility Test (NET) Certificate by ASRB, New Delhi, 1999
- Certificate of Merit by University of Agricultural Sciences, Bangalore for first rank in Masters Degree, 1999
- University Merit Scholarship by University of Agricultural Sciences, Bangalore, during undergraduate studies 1996- 1997
At Institute
- Director, Nitte Centre for Science Education & Research (NCSER)
- Chairperson, Internal Quality Assurance Cell (IQAC), NCSER
- Chairperson, Board of Studies in Life Sciences, NUCSER
- Chairperson, Anti-Ragging Committee, NUCSER
- Chairperson, Institutional Ethics Committee, NUCSER
- Chairperson, Scientific Review Committee, NUCSER
- Chairperson, Institutional Committee Against Substance Abuse, NUCSER
- Chairperson, Students Grievance Cell, NUCSER
- Chairperson, Institutional Women Cell, NUCSER
- Chairperson, Institutional Placement and Career Guidance Cell, NUCSER
- Chairperson, Library Committee, NUCSER
- Chairperson, Institutional Public Relations Committee, NUCSER
- Chairperson, Youth Red Cross Advisory Committee, NUCSER
- Chairperson, Information and Communication Technology Cell, NUCSER
- Chairperson, Green Initiative Committee, NUCSER
- Dean, Faculty of Biological Sciences, Nitte (Deemed to be University)
- Member, Academic Council, Nitte (Deemed to be University)
- Member, Institution Innovation Council, Nitte (Deemed to be University)
- Member Secretary, Strategic Planning Sub-committee, Nitte (Deemed to be University)
- Chief Coordinator, Grants Cell, Nitte (Deemed to be University)
- Member, Board of Research Studies, Faculty of Biological Sciences, Nitte (Deemed to be University)
- Member, Institutional Biosafety Committee, Nitte (Deemed to be University)
- Life member, Indian Society of Developmental Biology
- Life member, Molecular Pathology Association of India
- Life member, The Society of Biological Chemists, India
- Life member, Indian Association for Cancer Research
- Life member, Association of Microbiologists of India
- Life member, Indian Association of Biomedical Scientists
- Member, Asian Fisheries Society, Indian Branch
Conference/Journal Publications:
Selected Publications (Last three years)
Google Scholar: https://scholar.google.co.in/citations?user=g-vUFywAAAAJ&hl=en
ResearchGate: www.researchgate.net/profile/Anirban_Chakraborty12
Sponsored Research
Extramural Funding
Intramural Funding
Selected Publications (Last three years)
- Harshitha, M., D'Souza R, Disha S, Akshath US, Dubey S, Munang'andu, H.M., Chakraborty, A., Karunasagar, I., Maiti, B. Polylactic-co-glycolic acid polymer-based nano-encapsulation using recombinant maltoporin of Aeromonas hydrophila as potential vaccine candidate. Molecular Biotechnology [IF:2.6] Q2 (in press)
- Nayak, A., Harshitha, M., Dubey, S., Munang'andu, H.M., Chakraborty, A., Karunasagar, I., Maiti, B. 2023. Evaluation of probiotic efficacy of Bacillus subtilis RODK28110C3 against pathogenic Aeromonas hydrophila and Edwardsiella tarda using in vitro studies 2 and in vivo gnotobiotic zebrafish gut model system. Probiotics and Antimicrobial Proteins [IF: 4.9] Q1(In press)
- Ravindra J, Undiganalu GY, Nanjappa DP, Kallada K, Dhakal R, Chakraborty A*, Chakraborty G. 2023. Allicin extracted from Allium sativum shows potent anti-cancer and antioxidant properties in zebrafish. Biomedicine & Pharmacotherapy 169:115854 [IF:7.5] Q1
- Nayak, A., Harshitha, M., Disha S, Munang'andu, H.M., Karunasagar, I., Chakraborty A., Maiti B. 2023. Use of gnotobiotic zebrafish gut model and in vitro studies to determine the probiotic efficacy of Bacillus subtilis TLDK301120C24 isolated from Tilapia against warm water fish pathogens. Microbial Pathogenesis 185:106429 [IF: 3.8] Q2
- Harshitha M, Nayak A, Disha S, Akshath US, Dubey S, Munang'andu, H.M, Chakraborty, A., Karunasagar, I., Maiti, B. 2023. Nanovaccines to Combat Aeromonas hydrophila Infections in Warm-water Aquaculture: Opportunities and Challenges. Vaccines 11(10), 1555 [IF 7.8] Q1
- Dhakal R, Kallada K, Singh A, Nanjappa DP, Ravindra J, Vittal R, Sil SK, Chakraborty A, Chakraborty G. 2023. Investigation of anti-proliferative and anti-angiogenic properties of Parkia javanica bark and fruit extracts in zebrafish. PLoS ONE Jul 21;18(7):e0289117 [IF:3.75] Q1
- Mohan M, Gaonkar A, Kallada K, Nanjappa DP, Vittal R, Chakraborty A, Chakraborty G. 2023. Screening for microplastics in drinking water and its toxicity profiling in zebrafish. Chemosphere 341:139882 [IF:8.8] Q1
- Nanjappa DP, Saffel HD, Kalladka K, Arjuna S, Babu N, Prasad K, Sips P, Chakraborty A*. 2023. Poly (A)‐specific ribonuclease deficiency impacts oogenesis in zebrafish. Scientific Reports. 13:10026. [IF: 4.99] Q1
- Jerome MS, Nanjappa DP, Chakraborty A*, Chakrabarty S. 2023. Molecular etiology of defective nuclear and mitochondrial ribosome biogenesis: Clinical phenotypes and therapy. Biochimie. 207: 122-1365 [IF:4.37] Q2
- Venkataram R, Shetty V, Prasad K, Kille S, Srinivas T, Chakraborty A*. 2023. Detection of clinically-relevant EGFR variations in de novo small cell lung carcinoma by droplet digital PCR. Monaldi Archives for Chest Disease. 93:2280. Q3
- D'Souza J M, Chakraborty A, Kamath N. 2023. Intergenerational communication and elderly well-being. Clinical Epidemiology and Global Health. 20:101251
- Nanjappa DP, Chakraborty A*. 2023. Single nucleotide polymorphism in the genomic target affects the recombination efficiency of CRISPR/Cas9-mediated gene editing in zebrafish. Gene Reports 30:101737. Q4 [IF 1.3]
- Madhura RJ, Varsha A, Chakraborty A, Mohana Kumar B, Shetty V, Badanthadka B. 2023. Protein malnutrition in BALB/C mice: A model mimicking clinical scenario of marsamic-kwashiorkor malnutrition. Journal of Pharmacological and Toxicological Methods 119:107231 [IF 1.9] Q3
- Kotian A, Aditya V, Sheikh J, Saikrishnan S, Rai P, Chakraborty A, Karunasagar I, Deekshit VK. 2022. Effect of NaCl, high iron, iron chelator and antibiotics on growth, virulence gene expression and drug susceptibility in non-typhoidal Salmonella - an in vitro fitness study. Archives of Microbiology. 204,667 [IF: 2.60] Q2
- Bhat S, Mittal B, Nanjappa DP, Chakraborty G, Shetty S, Khanna-Gupta A, Chakraborty A*. 2022. Identification of a novel TNFRSF11A gene variant in a rare case of familial osteopetrosis autosomal recessive type 7. Gene Reports 29:101683. Q4 [IF 1.3]
- Prabhakara MA, Nanjappa DP, Kotian A, Krithika K, Chakraborty C, Vittal R, Raj JRM, Deekshit VK, Chakraborty A*. 2022. Wild type and cancer-prone zebrafish exhibit distinct gut microbial diversity and show differential anti-inflammatory response upon infection. Journal of Biosciences 47:65 [IF: 2.79] Q1
- Shenoy RD, Shetty V, Dheedene A, Menten B, Nanjappa DP, Chakraborty G, Sips P, de Paepe A, Callewaert B, Chakraborty A*. 2022. Phenotypic and molecular heterogeneity in Mandibulofacial Dysostoses: A case series from India. The Cleft Palate-Craniofacial Journal 59: 1346-1351 [IF:1.43] Q3
- Nayak A, Karunasagar I, Chakraborty A, Maiti B. 2022. Potential application of bacteriocins for sustainable aquaculture. Reviews in Aquaculture 14:1234-1248. [IF:10.59] Q1
- Babu N, Nanjappa DP, Nazareth S, Arjuna S, Chakraborty A*. 2022. PARN knockdown in cell lines results in differential and cell-specific alterations in the expression of cancer-associated mRNAs. Asian Pacific Journal of Cancer Prevention 23 (1): 207-215 Q2
- Babu N, Nanjappa DP, Arjuna S, V R, Shetty V, Chakraborty A*. 2021. Expression of Poly(A)- specific ribonuclease in solid tumours and hematopoietic malignancies. Journal of Clinical and Diagnostic Research Vol-15(12): XC16-XC19. Q3
- Nanjappa DP, Babu N, Khanna-Gupta A, O'Donohue M-F, Sips P, Chakraborty A*. 2021. Poly (A)-specific ribonuclease (PARN): More than just "mRNA stock clearing". Life Sciences 285:119953 [IF: 5.03] Q1
- Vineet Kulkarni, Sukanya Shetty, Subramanya K, Anirban Chakraborty, Prakash Patil, Roopa Bhandary, Rashmi Kundapur. 2021. Correlation of serum lipoprotein (a) levels with angiographic lesion severity in coronary artery disease. Biomedical and Biotechnology Research Journal 5:458-462 Q4
- Audrey D'Cruz, Dechamma Pandyanda Nanjappa, Sahana Maben, Pushparaja Shetty, Anirban Chakraborty*. 2021. Non-invasive saliva-based detection of gene mutations in oral cancer patients by Oral Rub and Rinse technique. Asian Pacific Journal of Cancer Prevention 22 (10) 3287-3291 Q2
- Bharti Mittal, Dechamma Pandyanda Nanjappa, Gunimala Chakraborty, Anirban Chakraborty*, Arati Khanna-Gupta. 2021. A patient with Lesch-Nyhan Syndrome presenting with anesthetic challenges: not an exception, but the rule. Gene Reports 24:101289 Q4 [IF 1.3]
- Harshitha KP, Dechamma PN, Nishith B, Krithika Kalladka, Shanti Priya Dias, Gunimala Chakraborty, Sudhindra M Rao, Anirban Chakraborty*. 2021. TP53 Codon 72 polymorphism and Type 2 Diabetes: A case-control study in South Indian Population. Molecular Biology Reports 48: 5093-5097 [IF: 2.31] Q4
- Venkataram R, Arjuna S, Hosmane GB, Chakraborty A*. 2021. Quantitative analysis of cell-free DNA by droplet digital PCR reveals the presence of EGFR mutations in non-malignant lung pathologies. Monaldi Archives for Chest Disease 91:1748. Q3
- Jazeela K, Chakraborty A, Kotian A, Aditya V, Ballamoole KK, Rai P, Karunasagar I, and Deekshit VK. 2021. Phenotypic characterization of auxotrophic mutant of nontyphoidal Salmonella and determination of its cytotoxicity, tumor inhibiting cytokine gene expression in cell line models Archives of Microbiology 203:2925-2939 [IF: 2.55] Q3
- Alva P P, Suresh S, Nanjappa D P, James J P, Kaverikrishna R, Chakraborty A, Sarojini B K, Harsha R. 2021. Isolation and identification of quorum antagonist from Cinnamomum verum leaves against Pseudomonas aeruginosa. Life Sciences 267:118878 [IF: 5.03] Q1
Google Scholar: https://scholar.google.co.in/citations?user=g-vUFywAAAAJ&hl=en
ResearchGate: www.researchgate.net/profile/Anirban_Chakraborty12
Sponsored Research
Extramural Funding
- The association of ACE2 and TMPRSS2 gene polymorphisms with susceptibility and severity to COVID-19 in Indian population and validation using zebrafish model system, Principal Investigator, Funded by ICMR, 2022-2025
- Combating cancer through alternative approaches: Investigating the antitumor properties of non-typhoidal Salmonella in transgenic zebrafish cancer models, Principal Investigator, Funded by ICMR, 2021-2024
- Investigating the mechanisms of genetic disorders using the zebrafish model system (GEN-ZEMO), Principal Investigator, Funded by DST-BELSPO, 2018-2021
- RNases and cancer: decoding the role of poly(A)-specific ribonuclease (PARN) in tumorigenesis, Principal Investigator, Funded by DST-SERB, 2017-2020
Intramural Funding
- Non-invasive detection of DNA methylation in lung cancer patients by droplet digital PCR, Principal Investigator, Funded by Nitte (Deemed to be University), 2020-2022
- Ribosomal defects and craniofacial deformities: A systematic genetic analysis of Treacher Collins syndrome (TCS) and TCS-like cases in India-Genotyping of patients, Principal Investigator, Funded by Nitte (Deemed to be University), 2018-2020
- Genetic testing of non-small cell lung cancers: Development of AS-LAMP assays for detection of EGFR and KRAS mutations, Principal Investigator, Funded by Nitte (Deemed to be University), 2016-2019
- Gene environment interaction in the development of asthma and allergic diseases: A study using Indian population, Principal Investigator, Funded by Nitte (Deemed to be University), 2016-2019
Currently enrolled PhD students: 4
Guided PhD students: 5
Guided PG Students: 18
Undergraduate-
Cancer Biology; Radiation Biology; Toxicology
Postgraduate-
Medical Genetics; Biology and Genetics of Cancer
Extramural Funding
- The association of ACE2 and TMPRSS2 gene polymorphisms with susceptibility and severity to COVID-19 in Indian population and validation using zebrafish model system, Principal Investigator, Funded by ICMR, 2022-2025
- Combating cancer through alternative approaches: Investigating the antitumor properties of non-typhoidal Salmonella in transgenic zebrafish cancer models, Principal Investigator, Funded by ICMR, 2021-2024
- Investigating the mechanisms of genetic disorders using the zebrafish model system (GEN-ZEMO), Principal Investigator, Funded by DST-BELSPO, 2018-2021
- RNases and cancer: decoding the role of poly(A)-specific ribonuclease (PARN) in tumorigenesis, funded by DST-SERB, 2017-2020
- Ribosomal defects and craniofacial deformities: A systematic genetic analysis of Treacher Collins syndrome (TCS) and TCS-like cases in India-Genotyping of patients, funded by NitteDU, 2018-2020
- Screening of gene mutations that interferes with response to CCRT in esophageal cancer patients: AS-LAMP assays using cell free DNA, funded by NitteDU, 2019-2021Genetic markers of Tuberculosis among Indo-Tibetan and Indian Population, funded by NitteDU, 2019-2021
- Impact of interaction with children on blood hormonal levels among institutionalized elderly, funded by NitteDU, 2019-2021
- In vitro cytotoxicity evaluation of denture materials used in the fabrication of RPD, funded by NitteDU, 2018-2020
- Effects of Titanium Surfaces on cell viability and cytokine expression in vitro, funded by NitteDU, 2018-2020
- Generation of transgenic zebrafish models for elucidating the molecular mechanisms of Mycobacterium infection, funded by NitteDU, 2018-2020
- Non-invasive detection of DNA methylation in lung cancer patients by droplet digital PCR, Principal Investigator, Funded by Nitte (Deemed to be University), 2020-2022
- Genetic testing of non-small cell lung cancers: Development of AS-LAMP assays for detection of EGFR and KRAS mutations, Principal Investigator, Funded by Nitte (Deemed to be University), 2016-2019
- Gene environment interaction in the development of asthma and allergic diseases: A study using Indian population, Principal Investigator, Funded by Nitte (Deemed to be University), 2016-2019
- Founder- Consortium of Rare Genetic and Bone Marrow Disorders India Network@NITTEDU (N-CRG.BMD|IN)
- Founder- The Cancer Gene Database@NitteDU(N-TCAG)
PROF. INDRANI KARUNASAGAR
- Designation Director (Projects & NuTEC), Coordinator for M.Sc. Marine Biotech
- Email indrani.karunasagar@nitte.edu.in
- Contact No. .
- Joining date
- Doctor of Philosophy (Medical Microbiology), Kasturba Medical College, 1985
- Master of Science (Microbiology), Kasturba Medical College, 1975
- International Jury Member of UNESCO for the International Life Science Research Award, 2013-2019.
- Research and Academic Excellence Award by Hindustan Group of Institutions, Hindustan University, 2017
- Sir. M. Visvesvaraya Award for excellence in research and lifetime contribution to Science and Technology, Govt. of Karnataka, 2014
- National Technology Development Award, Department of Biotechnology, Government of India, 2014
- Eminence in Virology Award, Amity University of Virology and Immunology, 2013
- Dr. T.S. Vasundhara Memorial Oration Award, Defense Food Research Laboratory, Mysore, 2012
- Dr. J.V. Bhat Endowment Oration Award, Manipal University, Manipal, 2012
- Fellow, National Academy of Agricultural Sciences, 2011 • TVR Pillay Foundation National award, 2008
- Rafi Ahmed Kidwai Award, Indian Council of Agricultural Research, 2007
- S. Swaminathan Award, Professional Fisheries Graduates Forum, India, 2005
- National Women Bio-scientist Lifetime achievement Award, Department of Biotechnology, Ministry of Science and Technology, India, 2003
- Vyas Memorial Award, Association of Microbiologists of India, 2002
- Outstanding Woman Scientist Award, Indian Council of Agricultural Research, 1998
- Laljee Godhoo Smarak Nidhi award, Association of Food Science and Technology, 1997
- Distinguished alumnus award, Kasturba Medical College, Manipal, 1990
- Certificate of appreciation, US Dept. of Agriculture for excellence in research, 1989
- Young Scientist award, Karnataka Association for Advancement of Science, 1986
- Scientific Advisor, International Foundation for Science, Sweden
- Member, National Scientific Advisory Council of DBT, Government of India
- Member, Programme Steering and Monitoring Committee (PSMC) under the Biotech Krishi Innovation Science Application Network (Biotech-KISAN)
- Advisor, Agricultural Scientists Recruitment Board (ICAR) ASRB for Recruitment of Scientists
- Rajesh, M.K., Muralikrishna, K.S., Nair, S.S., Kumar B.K., Subrahmanya, T.M., Sonu, K.P., Subaharan, K., Swetha, H., Keshava, P.T.S., Neeli, C., Karunasagar, I., Hebbar, K.B., Karun, A. (2020). Facile coconut inflorescence sap mediated synthesis of silver nanoparticles and its diverse antimicrobial and cytotoxic properties. Materials science & engineering: C. 111: 110834.
- Mohan Raj, J.R., Karunasagar, I. (2019) Phages amid antimicrobial resistance. Critical Reviews in Microbiology. 45:701-711.
- Rohit, A., Deekshit, V.K., Balaraj, M., Alandur, V.S., Abraham, G., Karunasagar, I., Karunasagar, I. (2019) CTX-M type extended-spectrum β-lactamase in Escherichia coli isolated from extra-intestinal infections in a tertiary care hospital in south India. Indian Journal of Medical Research. 149 (2):281-284
- Turner, L.M., Havenhand, J.N., Alsterberg, C., Turne,r A.D., Girisha, S.K., Rai, A., Venugopal, M.N, Karunasagar, I., Godhe, A. (2019) Toxic algae silence physiological responses to multiple climate drivers in a tropical marine food chain. Frontiers in Physiology. 10:373
- Anupama K. P, Chakraborty, A., Karunasagar, I., Karunasagar, I., Maiti., B. (2019) Loop-mediated isothermal amplification assay as a point-of-care diagnostic tool for Vibrio parahaemolyticus: Recent developments and improvements. Expert Review of Molecular Diagnostics 19(03): 229-239.
- D'Souza, C., Kumar, B.K., Kapinakadu, S., Shetty, R., Karunasagar, I., Karunasagar, I. (2018) PCR based evidence shows the presence of Vibrio vulnificus in wound infection cases in Mangaluru, India. International Journal of Infectious Diseases. 1:68:74-76.
- Yathisha, U.G., Bhat, I., Karunasagar, I., Mamatha, B.S. (2018) Antihypertensive activity of fish protein hydrolysates and its peptides. Critical Reviews in Food Science and Nutrition. 59:2363-2374
- Dubey, S., Avadhani, K., Mutalik, S., Sivadasan, S.M., Maiti, B., Girisha, S.K., Venugopal, M.N., Mutoloki, S., Evensen, O., Karunasagar, I., Munangandu, H.M. (2016) Edwardsiella tarda OmpA encapsulated in chitosan nanoparticles shows superior protection over inactivated whole cell vaccine in orally vaccinated fringed-lipped peninsula carp (Labeo fimbriatus). Vaccines 4(4): 40.
- Turner, L.M., Alsterberg, C., Turner, A.D., Girisha, S.K., Rai, A., Havenhand, J.N., Venugopal, M.N., Karunasagar, I., Godhe, A. (2016) Pathogenic marine microbes influence the effects of climate change on a commercially important tropical bivalve. Scientific Reports. 6:32413.
- Karunasagar, I., Karunasagar, I., Raghunath P. (2016); Editorial: Ecology, virulence and detection of pathogenic and pandemic Vibrio parahaemolyticus. Frontiers in Microbiology. 7:156.
- Rajesh, M.K., Muralikrishna, K.S., Nair, S.S., Kumar B.K., Subrahmanya, T.M., Sonu, K.P., Subaharan, K., Swetha, H., Keshava, P.T.S., Neeli, C., Karunasagar, I., Hebbar, K.B., Karun, A. (2020). Facile coconut inflorescence sap mediated synthesis of silver nanoparticles and its diverse antimicrobial and cytotoxic properties. Materials science & engineering: C. 111: 110834.
- Mohan Raj, J.R., Karunasagar, I. (2019) Phages amid antimicrobial resistance. Critical Reviews in Microbiology. 45:701-711.
- Rohit, A., Deekshit, V.K., Balaraj, M., Alandur, V.S., Abraham, G., Karunasagar, I., Karunasagar, I. (2019) CTX-M type extended-spectrum β-lactamase in Escherichia coli isolated from extra-intestinal infections in a tertiary care hospital in south India. Indian Journal of Medical Research. 149 (2):281-284
- Turner, L.M., Havenhand, J.N., Alsterberg, C., Turne,r A.D., Girisha, S.K., Rai, A., Venugopal, M.N, Karunasagar, I., Godhe, A. (2019) Toxic algae silence physiological responses to multiple climate drivers in a tropical marine food chain. Frontiers in Physiology. 10:373
- Anupama K. P, Chakraborty, A., Karunasagar, I., Karunasagar, I., Maiti., B. (2019) Loop-mediated isothermal amplification assay as a point-of-care diagnostic tool for Vibrio parahaemolyticus: Recent developments and improvements. Expert Review of Molecular Diagnostics 19(03): 229-239.
- D'Souza, C., Kumar, B.K., Kapinakadu, S., Shetty, R., Karunasagar, I., Karunasagar, I. (2018) PCR based evidence shows the presence of Vibrio vulnificus in wound infection cases in Mangaluru, India. International Journal of Infectious Diseases. 1:68:74-76.
- Yathisha, U.G., Bhat, I., Karunasagar, I., Mamatha, B.S. (2018) Antihypertensive activity of fish protein hydrolysates and its peptides. Critical Reviews in Food Science and Nutrition. 59:2363-2374
- Dubey, S., Avadhani, K., Mutalik, S., Sivadasan, S.M., Maiti, B., Girisha, S.K., Venugopal, M.N., Mutoloki, S., Evensen, O., Karunasagar, I., Munangandu, H.M. (2016) Edwardsiella tarda OmpA encapsulated in chitosan nanoparticles shows superior protection over inactivated whole cell vaccine in orally vaccinated fringed-lipped peninsula carp (Labeo fimbriatus). Vaccines 4(4): 40.
- Turner, L.M., Alsterberg, C., Turner, A.D., Girisha, S.K., Rai, A., Havenhand, J.N., Venugopal, M.N., Karunasagar, I., Godhe, A. (2016) Pathogenic marine microbes influence the effects of climate change on a commercially important tropical bivalve. Scientific Reports. 6:32413.
- Karunasagar, I., Karunasagar, I., Raghunath P. (2016); Editorial: Ecology, virulence and detection of pathogenic and pandemic Vibrio parahaemolyticus. Frontiers in Microbiology. 7:156.
- Multiple climate impacts as bottlenecks to the microbiome of the aquatic environment (Indo-Sweden-UK), funded by FORMAS, 2017-2020 [budget: 40 lakhs]
- Testing the potential of microalgae-bacteria consortium to manage pathogens in cultured shrimps (Indo-Sri Lanka), funded by Swedish Research Council, Sweden, 2017-2020 [Budget: 89 lakhs]
- Defence genes of tiger shrimp (Penaeus monodon) with respect to bacteria (Vibrio harveyi) and white spot virus (WSSV) infection, funded by DST-BELSPO, 2017-2020 [budget: 12.49 lakhs]
Dr. GUNIMALA CHAKRABORTY
- Designation Associate Professor G-II
- Email gunimala@nitte.edu.in
- Contact No. .
- Joining date 01-05-2018
Over the past 12 years I have worked on development of many new diagnostic techniques for a bacterial, viral pathogen as well as a parasite affecting humans using my expertise on LAMP technique and characterization (identification and function) of cytokines under different stress/infection. At present my research area and interest focusses on development of rapid molecular detection techniques, development of transgenic zebrafish lines for human diseases, Human /animal parasitology, and Molecular Immunology.
Doctor of Philosophy (Applied Biochemistry and Bioscience), University of Miyazaki, Japan, 2007
Master of Science (Aquaculture), West Bengal University of Animal Sciences, Kolkata, 2003
Associate Professor - Grade I, Nitte Centre for Science Education and Research, Mangaluru (2018-till date)
DST women Scientist, Nitte Centre for Science Education and Research, Mangaluru (2015 –2018)
Postdoctoral Fellow, (Infectious Diseases and Parasitology), Faculty of Medicine, University of Miyazaki, Japan (2010-2012).
Postdoctoral Fellow, (Biochemistry and Applied Science), Faculty of Agriculture, University of Miyazaki, Japan (2007 - 2009).
Zebrafish Model system: Transgenesis and disease modelling
Molecular detection techniques
Molecular Genetics
Bioinformatics
Human/animal parasitology
- Best Research Paper Awards 2020: Best Research Paper award of 2020 published from Nitte University Centre for Science Education and Research (NUCSER)
- DST women Scientist Fellow awarded by Department of Science and Technology, Govt. of India, 2015 -2018.
- Postdoctoral Fellow by University of Miyazaki, Department of Infectious Diseases and Parasitology, Faculty of Medicine, Japan,2010-2012
- Postdoctoral Fellow awarded by Japan Society for Promotion of Science, Japan, 2007 - 2009
- Rotary Yoneyama Fellowship for the doctoral studies awarded by Yoneyama Foundation of Japan, April 2005-March 2007
- North East Council (NEC) Fellowship during B.F.Sc. program, awarded by Manipur State Fisheries Department, India ,1997-2001
- Coordinator, Institutional Editorial committee
- Member, Institutional committee against substance abuse
- Member coordinator, Institutional Committee against sexual harassment
- Life Membership, IABMS
- Member, Society of Biological Chemist (India)
- Punja HK, Nanjappa DP, Babu N, Kalladka K, Dias BS, Chakraborty G, Rao SM, Chakraborty A. TP53 codon 72 polymorphism and type 2 diabetes: a case-control study in South Indian population. Molecular Biology Reports. 2021 Jun 28:1-5
- Mittal B, Nanjappa DP, Chakraborty G, Chakraborty A, Khanna-Gupta A. A patient with Lesch-Nyhan Syndrome presenting with anesthetic challenges: not an exception, but the rule. Gene Reports. 2021 Jul 23:101289
- Arjuna S, Venkataram R, Dechamma PN, Chakraborty G, Babu N, D'Cruz A, Hosmane GB, Chakraborty A. Non-invasive detection of EGFR mutations by cell-free loop-mediated isothermal amplification (CF-LAMP). Scientific reports. 2020 Oct 16;10(1):1-7
- Prabhakara Aprathi, Pandyanda Nanjappa Dechamma, Babu Nishith, Kalladka Krithika, Chakraborty Anirban, Chakraborty Gunimala*. Exposure to mosquito repellents causes profound development defects and induces oxidative stress in zebrafish. Journal of Health and Allied Sciences NU, :2020;10:122-127
- Shreya Kunder,Babu Nishith Pandyanda Nanjappa Dechamma, Kalladka Krithika, Chakraborty Gunimala, Chakraborty Anirban*. Evaluation of toxicity and antioxidant property of Cassia fistula stem bark extracts in zebrafish. Journal of Health and Allied Sciences NU:2020; 10:109-115
- Dinesh Deeksha, Pandyanda Nanjappa Dechamma, Babu Nishith, Kalladka Krithika, Chakraborty Gunimala, Chakraborty Anirban*. 2020.Evaluation of toxicity and anti-angiogenic activity of Murraya koenigii leaf extracts in zebrafish. J Health Allied Sci NU:2020; 10:79-85
- Srividya Arjuna, Gunimala Chakraborty, Rajesh Venkataram, Pandyanda Nanjappa Dechamma, Anirban Chakraborty.2020. Detection of epidermal growth factor receptor T790M mutation by allele-specific loop mediated isothermal amplification. Journal of Carcinogenesis
Selected Journal publications (last 5 years)-
- Manal Hassan Rajeshwari Vittal, Juliet Mohan Raj · Gunimala Chakraborty. Loop‑mediated isothermal amplification (LAMP): a sensitive molecular tool for detection of Staphylococcus aureus in meat and dairy product. Brazilian Journal of Microbiology. 2022. 53;341-347.
- Rajeshwari Vittal, Juliet Mohan Raj · Gunimala Chakraborty. Rapid detection of Salmonella spp from meat: Loop mediated isothermal amplification (LAMP). Journal of pure and Applied Microbiology.2022;16,
PhD : 02 (ongoing);
PG: 05 completed and 03 ongoing
UG: 06 completed
Undergraduate
Cell based assays in Biomedical Science, Genetic Engineering, Good Laboratory Practices
Postgraduate
Medical Biotechnology, Application Biotechnology in Food Science, Research Ethics & IPR
Cell based assays in Biomedical Science, Genetic Engineering, Good Laboratory Practices
Postgraduate
Medical Biotechnology, Application Biotechnology in Food Science, Research Ethics & IPR
Extramural Funding
- Liquid Biopsy for Lung Cancer: Development of LAMP assays using cell-free DNA for screening of gene mutations that interfere with response to TKIs in patients Principal Investigator, funded by ICMR, Govt. of India, 2020-2023
- The association of ACE2 and TMPRSS2 gene polymorphisms with susceptibility and severity to COVID-19 in Indian population and validation using zebrafish model system Co-Principal Investigator, funded by ICMR (covid Research), Govt. of India,2021-2024
Japan-Asia Youth Exchange program in Science for undergraduates (SAKURA exchange program in science) coordinator, 2018
Japan-Asia Youth Exchange program in Science (SAKURA exchange program in science) awardee, 2016
Dr. BISWAJIT MAITI
- Designation Associate Professor G-II
- Email maiti.b@nitte.edu.in
- Contact No. .
- Joining date 23-08-2013
Following Ph.D., Dr. Biswajit Maiti continued his research career at the College of Fisheries, Mangaluru. Later, he joined NUCSER as Assistant Professor in 2013. He has also worked as a visiting researcher in Food Microbiology at Obihiro University, Japan, during 2015 -2016. From the past decade, he has been working on the development of cutting-edge diagnostic methods for rapid detection microbial pathogens, deciphering outer membrane proteins based-antibiotic resistance of bacterial pathogens, and development of novel vaccines using biotechnological approaches. He has numbers of publications in scientific journals of repute, and book chapters to his credit, received research funds from various external agencies, and guiding students for their Ph.D., and postgraduate research dissertation.
Doctor of Philosophy (Bioscience), Mangalore University, 2012
Master of Science (Microbiology), Jiwaji University, 2006
- Associate Professor – Grade II, Nitte University Centre for science education and research, Mangaluru (2022- to date)
- Associate professor - Grade I, Nitte University Centre for science education and research, Mangaluru (2018- 2022)
- Assistant Professor, Nitte University Centre for science education and research, Mangaluru (2013- 2018)
- Post-doctoral fellow (Food Microbiology), Obihiro University, Hokkaido, Japan (2015 - 2016)
- Post-doctoral research associate, College of Fisheries, Mangaluru (2012 - 2013)
- Development of improved diagnostic methods for the pathogenic bacteria.
- Pathogenesis and membrane-based antibiotic resistance mechanisms of bacteria.
- Role of outer membrane proteins of pathogenic Gram-negative bacteria.
- Aquaculture and Marine Biotechnology.
- Dr. (Mrs.) Gouri Ganguly Memorial Award for Young Scientist, Indian Science Congress, 2018.
- Visiting researcher at Obihiro University, Japan, 2015
- WFCC-MIRCEN-WDCM meeting on Microbial Resources Management and Utilization, IMCAS, Beijing, China, 2014
- Young scientist award, Association of microbiologist of India, 2012
- Short-term research fellowship, Nofima AS, Tromsø, Norway, 2010
- TCDC Expert (laboratory management), FAO-UN, Dhaka, Bangladesh, 2010
- Member, Board of Studies in Biological Sciences (UG & PG), Nitte DU
- Member, Doctoral Studies Cell, Nitte DU
- Member Secretary, Research Advisory Committee, NUCSER
- Member Secretary, Information and Communication Technology Cell, NUCSER
- In-charge, Institutional Lab Vigilance Committee, NUCSER
- Member, Internal Quality Assurance Cell, NUCSER
- Member, Lab Resource Committee, NUCSER
- Member, Institutional Library Committee, NUCSER
- Member, Institutional Committee Against Substance Abuse, NUCSER
- Lifetime member, Indian Association of Biomedical Scientists (IABMS), 2021
- Lifetime member, Association of Food Scientists & Technologists (INDIA) AFST(I), 2021
- Lifetime member, The Society of Biological Chemists (SBC), 2015
- Lifetime member, Indian Science Congress Association (ISCA), 2014
- Lifetime member, The Biotech Research Society (BRSI), 2012
- Lifetime member, Association of Microbiologists of India (AMI), 2008
Selected Journal publications (last 5 years)-
Conference publications: 31
All Publications:
Google scholar: https://scholar.google.co.in/citations?user=1toWRp4AAAAJ&hl=en
Web of Science: https://www.webofscience.com/wos/author/record/J-9120-2019
Scopus: https://www.scopus.com/authid/detail.uri?authorId=34875362800
ORCiD: https://orcid.org/0000-0002-8231-7030
ResearchGate- https://www.researchgate.net/profile/Biswajit-Maiti-3
- Prerana, S., Ashwini, P., Anupama, K.P., Prajna, V.S., Prithvisagar, K.S., Nayak, A., Rai, P., Rohit, A., Karunasagar, I., Karunasagar, I., Maiti, B * (2023). Evaluation of reverse transcriptase-polymerase spiral reaction assay for rapid and sensitive detection of severe acute respiratory syndrome coronavirus 2. Clinica Chimica Acta 539: 144-150. [IF: 6.314]
- Deekshit, V.K., Maiti, B., Kumar, B.K., Kotian, A., Pinto, G., Melba G., Bondad-Reantaso, M.G., Karunasagar, I., Karunasagar, I. (2023). Antimicrobial resistance in fish pathogens and alternative risk mitigation strategies. Reviews in Aquaculture 15(1):261-273. [IF: 10.618].
- Akshay, S.D., Anupama, K.P., Deekshit, V.K., Rohit A., Maiti, B * (2022). Effect of sub-minimum inhibitory concentration of ceftriaxone on the expression of outer membrane proteins in Salmonella enterica serovar Typhi. World Journal of Microbiology and Biotechnology 38(11):190. [IF: 4.253]
- Rai, P., Anupama, K.P., Pai, A.P., Prerana, S., Prajna, V.S., Ballamoole, K.K., Maiti, B * (2022). Colorimetric reverse transcriptional loop-mediated isothermal amplification for rapid detection of SARS-CoV-2. International Journal of Infectious Diseases 116: S36. [IF: 12.074]
- Maiti, B *., Anupama, K.P., Rai, P., Karunasagar, I., Karunasagar, I. (2022). Isothermal amplification-based assays for rapid and sensitive detection of SARS-CoV-2: Opportunities and recent developments. Reviews in Medical Virology 32(2): e2274 [IF: 11.043]
- Nayak A, Karunasagar I, Chakraborty A, Maiti B *. (2022) Potential application of bacteriocins for sustainable aquaculture. Reviews in Aquaculture 14(3):1234-1248. [IF: 10.618].
- Anupama KP, Nayak A, Karunasagar I, Karunasagar I, Maiti B *. (2021). Evaluation of loop-mediated isothermal amplification assay along with conventional and real-time PCR assay for sensitive detection of pathogenic Vibrio parahaemolyticus from seafood sample without enrichment. Molecular Biology Reports 48(1):1009-1016. [IF: 2.742]
- Rajeish, M., Mani, M.K., Dechamma, M.M., Bossier, P., Rai, P., Karunasagar, I., Maiti, B *. (2021). Expression profile of heat shock protein 70 in lymphoid organs of Penaeus monodon in response to white spot syndrome virus infection. Aquaculture Research 52(3): 1316-1320. [IF: 2.184]
- Dechamma, MM., Mani, MK., Rajeish, M., Santhosh, KS., Akhila, DS., Maiti, B*., Bossier, P., Karunasagar, I., Karunasagar, I. (2020) Differential expression of akirin gene in black tiger shrimp Penaeus monodon in response to immunostimulant administration and infections with Vibrio harveyi and White spot syndrome virus. Journal of the World Aquaculture Society 51(4):1054-1065. [IF: 3.402]
- Anupama KP, Nayak A, Karunasagar I, Maiti B *. (2020) Rapid visual detection of Vibrio parahaemolyticus in seafood samples by loop-mediated isothermal amplification with hydroxynaphthol blue dye. World Journal of Microbiology and Biotechnology 36(5):76. [IF: 4.253]
- Maiti, B*., Dubey, S., Munang´andu, H.M., Karunasagar, I., Karunasagar, I., Evensen, Ø. (2020) Application of outer membrane protein-based vaccines against major bacterial fish pathogens in India. Frontiers in Immunology 11: 1362. [IF: 8.786]
- Srividya, A., Maiti, B., Chakraborty, A., Chakraborty, G (2019) Loop mediated isothermal amplification: A promising tool for screening genetic mutations. Molecular Diagnosis & Therapy 23(6):723-733. [IF: 4.476]
- Anupama K. P, Chakraborty, A., Karunasagar, I., Karunasagar, I., Maiti., B*. (2019) Loop-mediated isothermal amplification assay as a point-of-care diagnostic tool for Vibrio parahaemolyticus: Recent developments and improvements. Expert Review of Molecular Diagnostics 19(03): 229-239. [IF: 5.670]
- Dubey, S., Maiti, B., Kim, S., Sivadasan, S.M., Kannimuthu, D., Pandey, P.K., Girisha, S.K., Mutoloki, S., Chen, S., Evensen, Ø., Karunasagar, I., Munang´andu, H.M. (2019) Genotypic and phenotypic characterization of Edwardsiella isolates from different fish species and geographic areas in Asia: Implications for vaccine development. Journal of Fish Diseases 42(6):835-850. [IF: 2.58]
- Choudhury, T., Maiti, B., Venugopal, M.N., Karunasagar, I. (2019) Influence of some environmental variables and addition of r-lysozyme on efficacy of Vibrio harveyi phage for therapy. Journal of Biosciences 44(1):8. [IF: 2.795]
- Anupama, K.P., Deeksha, K., Deeksha, A., Karunasagar, I., Karunasagar, I. Maiti, B *. (2019) Comparative performance of TCBS and TSA for the enumeration of trh+ Vibrio parahaemolyticus by direct colony hybridization. Journal of Microbiological Methods 157: 37-42. [IF: 2.622]
- Maiti B., Nayak, S., Anupama, K.P. Specific primers to detect Acinetobacter baumannii with loop-mediated isothermal amplification assay. Application number: 202241073827; Publication Number: 02/2023; Publication Date: 13/01/2023.
- Maiti, B., Rai, P., Anupama, K.P., Kumar, B.K. Unique primers for rapid detection test for SARS- CoV-2 using loop-mediated isothermal amplification. Application number: 202141030297; Publication Number: 34/2022; Publication Date: 26/08/2022
- Maiti, B., Rai, P., Anupama, K.P. Unique molecular primers to detect SARS- CoV-2 by polymerase spiral reaction assay. Application Number: 202141030214; Publication Number: 36/2022; Publication Date: 09/09/2022.
Conference publications: 31
All Publications:
Google scholar: https://scholar.google.co.in/citations?user=1toWRp4AAAAJ&hl=en
Web of Science: https://www.webofscience.com/wos/author/record/J-9120-2019
Scopus: https://www.scopus.com/authid/detail.uri?authorId=34875362800
ORCiD: https://orcid.org/0000-0002-8231-7030
ResearchGate- https://www.researchgate.net/profile/Biswajit-Maiti-3
PhD students: 01 (completed), 05 (ongoing)
PG Students: 08 (completed), 03 (ongoing)
UG Students: 11 (completed), 02 (ongoing)
UG/PG Internship: 03
Undergraduate-
Genetic Engineering and Biotechnology; Fundamentals of Immunology; Bioinformatics; Molecular Biology
Postgraduate-
Medical Biotechnology; Immunology; Cell and Molecular Biology
Extramural Funding
- Deciphering outer membrane protein-based resistance of bacteria to antibiotics and bacteriophage for effective control of multidrug-resistant Acinetobacter baumannii, Principal Investigator, funded by ICMR, 2020-2023
- Biotechnological approaches for prevention and control of fish disease in aquaculture (BIOAQUA), Principal Investigator, funded by DST (Indo-Norway joint research project), 2019-2022
- Rapid and sensitive detection of novel coronavirus (SARS-CoV-2) using isothermal nucleic acid amplification, Principal Investigator, funded by SERB, 2020-2021
- Development of novel methods for the sensitive detection and enumeration of Vibrio parahaemolyticus, Principal Investigator, funded by DBT, 2016-2019
- Understanding the role of membrane proteins in the multidrug-resistant clinical strain of Salmonella, Principal Investigator, funded by NitteDU, 2018-2020
Convener, Biotechnology in one health for pre-university college students sponsored by BRSI under the scheme Biotechnology popularization and skill development, 2019-2020.
Dr. PRAVEEN RAI
- Designation Associate Professor G-II
- Email raiprav@nitte.edu.in
- Contact No. .
- Joining date 16-08-2014
Dr. Praveen Rai did PhD (Molecular Virology) from Karnataka Veterinary, Animal and Fisheries Sciences University, Bidar. He joined NUCSER in 2014. He has 36 research publications in highly rated journals of international standard, mostly related to molecular characterization of microbial pathogens. Currently, his research focuses on molecular characterization of Dengue and Rotaviruses, development of point of care diagnostics for SARS-CoV-2, Dengue virus, Human Papillomavirus (HPV), Malaria Parasite and Leptospira, Screening of antiviral compounds, Host-Pathogen Interaction, RNA Interference and Phage based biocontrol technologies. His research work is supported by various agencies such as SERB, DST, DBT, ICMR and Nitte (DU).
- Master of Science (Microbiology), Karnataka Veterinary, Animal and Fisheries Sciences University, 2008
- Doctor of Philosophy (Microbiology), Karnataka Veterinary, Animal and Fisheries Sciences University, 2013
- Associate Professor – Grade II, Nitte University Centre for science education and research, Mangaluru (2022- to date)
- Associate professor - Grade I, Nitte University Centre for science education and research, Mangaluru (2018- 2022)
- Epidemiology and molecular characterization of human and animal viruses
- Host-pathogen Interaction
- Molecular diagnostics
- RNA interference
- Phage based biocontrol technologies
- Young Scientist Award, DST-SERB, Gov. of India, 2015-2018
- SAKURA science award, University of Miyazaki, Japan, 2015
- Dr. C.V Kulakarni Award for the Best PhD research, 2013 • Dr. N. R Menon Award for the Best Indian M.Sc. Thesis, 2009. • Dr. Jalihal Endowment Award for the All-India best Master's Degree Research in Fisheries, 2008-2009.
- Coordinator, Staff Development Centre, NUCSER
- Member, Institutional Academic and Administrative Audit Committee, NUCSER
- Member, Institutional Committee for Development of Professional Competence in Teaching, NUCSER
- Institutional Research Coordinator, NUCSER
- Member Secretary, Biological Sciences Education Unit, NUCSER
- Member, Research Cell, NUCSER
- Subject Expert, Scientific Committee, Nitte DU
- Member, Institutional Ethical Committee, NUINS
- Member, Sub-Committee of the Board of Research Studies, Nitte DU
- Member, Institutional Committee Against Substance Abuse, NUCSER
- Member, Institutional Academic committee, NUCSER Member, Hostel Committee, NUCSER
- Member, International Society of Infectious Diseases, USA.
- Life Member, Society of Biological Chemists, India
- Life Member, Association of Microbiologists of India (AMI), India
- Member, Professional Fisheries Graduates' Forum (PFGF), India
- Member, College of Fisheries Alumni Association, Mangalore, India
Journal publications:
Google scholar ID: https://scholar.google.com/citations?user=9Yr9nlIAAAAJ&hl=en
Research Gate: https://www.researchgate.net/profile/Praveen_Rai
Web of Science Researcher ID: ABE-8528-2020
Orcid ID: 0000-0002-3695-4178
Scopus ID: 26030010600
Conference publications: 25
Patents Published
- Prerana S, Ashwini P, Anupama KP, Prajna VS, Prithvisagar KS, Nayak A, Rai P, Rohit A, Karunasagar I, Karunasagar I, Maiti B. Evaluation of reverse transcriptase-polymerase spiral reaction assay for rapid and sensitive detection of severe acute respiratory syndrome coronavirus 2. Clinica Chimica Acta. 2023 Jan 15. 539: 144-150
- Maiti B, Anupama KP, Rai P, Karunasagar I, Karunasagar I. Isothermal amplification‐based assays for rapid and sensitive detection of severe acute respiratory syndrome coronavirus 2: Opportunities and recent developments. Reviews in Medical Virology. 2022 Mar;32(2):e2274.
- Rai P, Shetty SS, Prabell S, Kuntar A, Pinto D, Kumar BK, Divyashree M, Raj JR, Premanath R, Deekshit VK, Karunasagar I. Characterisation of broad-spectrum phiKZ like jumbo phage and its utilisation in controlling multidrug-resistant Pseudomonas aeruginosa isolates. Microbial Pathogenesis. 2022 Nov 1;172:105767.
- Ashwath P, Deekshit VK, Rohit A, Rai P, Aditya V, Babu N, Karunasagar I, Dharnappa Sannejal A. Sequence-Specific Gene Silencing of acrA in the Multi-drug Efflux System AcrAB Induces Sensitivity in Drug-Resistant Klebsiella pneumoniae. Molecular Biotechnology. 2022 Nov 15:1-8.
- Badekila AK, Rai P, Kini S. Identification and evaluation of an appropriate housekeeping gene for real time gene profiling of hepatocellular carcinoma cells cultured in three dimensional scaffold. Molecular Biology Reports. 2022 Jan;49(1):797-804.
- Rai P, Kumar BK, Deekshit VK, Karunasagar I, Karunasagar I. Detection technologies and recent developments in the diagnosis of COVID-19 infection. Applied Microbiology and Biotechnology. 2021 Jan 4:1-5.
- Kumar BK, Rohit A, Prithvisagar KS, Rai P, Karunasagar I, Karunasagar I. Deletion in the C-terminal region of the envelope glycoprotein in some of the Indian SARS-CoV-2 genome. Virus Research. 2021 Jan 2;291:198222.
- Venkatraja B, Srilakshminarayana G, Kumar BK, Hegde MN, Kanchan J, Karuvaje G, Rai P. Preliminary Evidence from a Cross-sectional Study on Epidemiology and Early Transmission Dynamics of COVID-19 in Karnataka State of India. Journal of Health and Allied Sciences NU. 2021 May 11.
- Apine E, Rai P, Mani MK, Subramanian V, Karunasagar I, Godhe A, Turner LM. Comparative analysis of the intestinal bacterial communities in mud crab Scylla serrata in South India. MicrobiologyOpen. 2021 Apr;10(2):e1179.
- Rai P, Kille S, Kotian A, Kumar BK, Deekshit VK, Ramakrishna MS, Karunasagar I, Karunasagar I. Molecular investigation of the dengue outbreak in Karnataka, South India, reveals co-circulation of all four dengue virus serotypes. Infection, Genetics and Evolution. 2021 Aug 1;92:104880.
- D'Souza, C., Kumar, B.K., Rai, P., Deekshit, V.K., Karunasagar, I., (2019). Application of gyrB targeted SYBR green based qPCR assay for the specific and rapid detection of Vibrio vulnificus in seafood. J Microbiol Methods. 2019 Nov;166:105747.
Google scholar ID: https://scholar.google.com/citations?user=9Yr9nlIAAAAJ&hl=en
Research Gate: https://www.researchgate.net/profile/Praveen_Rai
Web of Science Researcher ID: ABE-8528-2020
Orcid ID: 0000-0002-3695-4178
Scopus ID: 26030010600
Conference publications: 25
Patents Published
- Praveen Rai; Krishna Kumar B; Deekshit; Juliet MohanRaj. Consortium of Broad-spectrum jumbo bacteriophages for control of multidrug resistant Pseudomonas aeruginosa. Application no. 202141044837.
- Biswajit Maiti; Praveen Rai; Karanth Padyana Anupama. Unique molecular primers to detect SARS- CoV-2 by polymerase spiral reaction assay. Application no. 202141030214
- Biswajit Maiti; Praveen Rai; Karanth Padyana Anupama; Krishna Kumar Ballamoole. Unique primers for rapid detection test for SARS- CoV-2 using loop-mediated isothermal amplification. Application no. 202141030297
PhD students: 05 (ongoing)
PG Students: 09 (completed)
UG Students: 06 (completed): Other students: 02
Undergraduate:
- Basics of Molecular Biology
- Medical Virology
- Biosafety and Bioethics
- Human Pathology
- Cell and Molecular Biology
- Molecular Diagnostics
Ongoing:
As PI:
As PI:
As PI:
- Development of immunofluorescent nanodiagnostic assay as a point-of-care detection of dengue virus, Funded by DST-BDTD, 2021-2023 [Budget: 21.86 lakhs]
- Development of monoclonal antibody against NS1 and E proteins of dengue virus, Funded by Nitte (DU), 2019-2021 [Budget: 1.9 lakhs].
- Antiviral properties of four medicinal plant extracts against dengue virus, Funded by Nitte (DU), 2018-2020 [Budget: 1.6 lakhs].
- Elucidation of platelet activation and NLRP3 inflammasome response in platelets during invasive Vibrio vulnificus infection to understand its potential role in the immunopathogenesis- Funded by ICMR, 2022-2025 [Budget: 27.62 lakhs].
- Evaluation of cellular and organismal cytotoxicity of Arecanut aqueous extract- Funded by CAMPCO, 2021-2022.
- A novel dietary approach for foetal programming of major chronic disorders in adult life using Albino Wistar Rats-an experimental case control study, Funded by ICMR, 2019-2022 [Budget: 23.0 lakhs].
- Tracing the molecular epidemiology of Leptospirosis and assessing its zoonotic transmission potential in Dakshina Kannada District, Karnataka, Funded by Nitte (DU), 2019-2021 [Budget: 1.9 lakhs].
- Development of a cancer model in three dimensional scaffolds for biomedical applications, Funded by Nitte (DU), 2019-2021 [Budget: 1.9 lakhs]
As PI:
- Biocontrol of pathogenic Vibrio parahaemolyticus in culture systems using bacteriophages, Funded by DST-SERB, 2015-2018 [Budget: 22.40 lakhs].
- Isolation and molecular characterization of bacteriophage against Pseudomonas aeruginosa, Funded by Nitte (DU), 2016-2017 [Budget: 1.15 lakhs].
- Rapid and sensitive detection of novel coronavirus (SARS-CoV-2) using isothermal nucleic acid amplification, Funded by DST-SERB, 2020-2021 [Budget: 17.46 Lakhs].
- Novel RNAi therapeutic approach to combat multidrug resistance in Klebsiella species, funded by NitteDU, 2018-2020 [Budget: 1.80 lakhs]
- Development of novel methods for the sensitive detection and enumeration of Vibrio parahaemolyticus, Funded by DBT, 2016-2019 [Budget: 29.0 lakhs].
- Biofilm formation and virulence gene expression in environmental and clinical isolates of Pseudomonas aeruginosa, Funded by Nitte (DU), 2016-2017 [Budget: 1.2 lakhs].
- Abstracts in national/ international conference: 15
- Abstracts in national/ international conference: 14
- Nucleotide sequence submissions to NCBI GenBank: 60
- Expressed sequence tag sequence submissions: 4984
- Whole genome sequence (Bacteria/Viruses/Bacteriophages) submission:10
- Invited Talks /Oral Presentation (National/International): 02
- National / International workshops / conferences / symposium attended: 30
Dr. DEEKSHIT
- Designation Associate Professor G-I
- Email deekshit1486@nitte.edu.in
- Contact No. .
- Joining date 16-08-2014
Dr. Deekshit completed his PhD (Microbiology) from Manipal University and had been worked as a research associate at UNESCO MIRCEN for Marine Biotechnology (KVAFSU), Mangalore. He did his short-term post-doc at University College Dublin, Ireland in the year 2018. His research focus includes molecular characterization of nontyphoidal Salmonella with special consideration to their antibiotic resistance mechanism which led to the detection of class 1 integrons in Salmonella Weltevreden and silent antibiotic resistance genes in some non-typhoidal isolates of Salmonella. Further, he developed a PCR for the simultaneous detection of Salmonella Pathogenicity Island 2 and its antibiotic resistance genes. He has also developed a Miss Match mutation PCR assay for the detection of QRDR mutation in fluoroquinolone resistant E. coli. His research interest includes identifying the characteristics of multidrug resistant gut pathogens in simulated gut condition, developing nanobiotics against MDR gut pathogens and determining the anticancer ability non-typhoidal Salmonella in vitro.
- Master of Fisheries Microbiology (M.FSc.), KVAFSU, 2009
- Doctor of Philosophy (Microbiology), Manipal University, 2014
- Associate Professor G-I, Nitte University Centre for Science Education and Research (2022-till date)
- Assistant Professor G-II, Nitte University Centre for Science Education and Research (2018- 2022)
- Assistant Professor G-I, Nitte University Center for Science Education and Research (2014-2018)
- Research Associate, KVAFSU (2012-2014)
- Infectious Disease Biology (Bacteriology)
- Antimicrobial Resistance
- Molecular Biology & Biotechnology
- Best Teacher Award 2021 (NUCSER)
- Best Researcher Award 2019, Nitte (Deemed to be University)
- Best Researcher Award 2019, NUCSER
- ITS-DST SERB Travel grant to attend IMED-2018, Vienna
- The diligent employee of the year award (NUCSER), 2017
- EMBO short term Fellowship, University College Dublin, 2018
- DST-SERB Early Career Research Award, 2017
- Sakura Science Award, Miyazaki, Japan, 2015
- College of Fisheries Alumni Association (COFAA) certificate of appreciation for academic excellence for the year, 2007
- University merit scholarship by KVAFSU, Bidar, during post-graduate studies (2007-2009)
- University merit scholarship by KVAFSU, Bidar, during undergraduate studies (2003-2007)
- Member, Antiaging Committee, NUCSER
- Member, Institutional committee against sexual harassment, NUCSER
- Member, Information and Communication Technology Cell, NUCSER
- In-charge, Academic Committee, NUCSER
- Coordinator, NUeLearn 2020-21, NUCSER
- Member, Institutional COVID-19 task force, NUCSER
- Member, Association of Microbiologists of India (AMI), India
- Member, Professional Fisheries Graduates' Forum (PFGF), Mumbai, India.
- Member, Indian Association of Biomedical Scientists (IABMS), Tamil Nadu, India
- Rani, M.S., Rohit. A., Aditya, V., Shetty, V.P., Kotian, A., Mohanapriya, P., Rai. P., Karunasagar, I., Deekshit, V. K. (2021) Comparative analysis of different methods used for molecular characterization of Burkholderia cepacia complex isolated from noncystic fibrosis conditions Indian Journal of Medical Microbiology, (In Press)
- Aditya, V., Kotian, A., Saikrishnan, S., Rohit, A., Divyashree, M., Karunasagar, I., Deekshit, V.K. (2021) Effect of ciprofloxacin and in-vitro gut conditions on biofilm of Escherichia coli isolated from clinical and environmental sources. Journal of Applied Microbiology. (In Press)
- Jazeela, K., Chakraborty, A., Kotian, A., Aditya, V., Kumar, B.K., Rai, P., Karunasagar, I., Deekshit, V.K. (2021). Phenotypic characterization of auxotrophic mutant of nontyphoidal Salmonella and determination of its cytotoxicity, tumor inhibiting cytokine gene expression in cell line models. Archives of Microbiology, 203(6), 2925-2939
- Rai, P., Kumar, B.K., Deekshit, V.K., Karunasagar, I., Karunasagar, I. (2021) Detection technologies and recent developments in the diagnosis of COVID-19 infection. Applied Microbiology and Biotechnology,105(2), 441-455
- Caroline D'Souza, Prithvisagar K. S., Deekshit, V.K., Karunasagar, I., Karunasagar, I. and Kumar B. K. (2020) Exploring the Pathogenic Potential of Vibrio vulnificus Isolated from Seafood Harvested along the Mangaluru Coast, India. Microorganisms, 1-15
- Akshatha, K., Aditya, V., Jazeela, K., Karunasagar, I., Karunasagar, I., Deekshit V.K., (2020) Effect of bile on growth and biofilm formation of multidrug resistant and sensitive non-typhoidal Salmonella serovars isolated from seafood and poultry. Research in Microbiology. 171;165-173
- Jazeela, K., Chakraborty, A., Karunasagar, I., Deekshit, V.K. (2020). Nontyphoidal Salmonella: a potential anticancer agent. Journal of applied microbiology. 128(1):2-14
- Deekshit, V.K., Jazeela, K., Chakraborty, G., Rohit, A., Chakraborty, A., Karunasagar, I. (2019) Mismatch amplification mutation assay-polymerase chain reaction: A method of detecting fluoroquinolone resistance mechanism in bacterial pathogens. Indian Journal of Medical Research.149(2):146-150
- Jazeela, K., Chakraborty, G., Shetty, S.S., Rohit, A., Karunasagar. I., Deekshit, V.K. (2019) Comparison of Mismatch Amplification Mutation Assay PCR-and PCR-Restriction Fragment Length Polymorphism for Detection of Major Mutations in gyrA and parC of Escherichia coli Associated with Fluoroquinolone Resistance. Microbial Drug Resistance 25(1):23-31
Patent filed: 01
- Deekshit VK, Maiti B, Kumar BK, Kotian A, Pinto G, Reantaso M, Karunasagar I, Karunasagar I. Antimicrobial resistance in fish pathogens and alternative risk mitigation strategies. Reviews in Aquaculture, 2022.
- Deekshit VK, Srikumar S. 'To be, or not to be'-The dilemma of 'silent'antimicrobial resistance genes in bacteria. Journal of Applied Microbiology. 2022 Nov;133(5):2902-14.
- Aditya V, Kotian A, Sanil A, Thaseena PM, Karunasagar I, Deekshit VK. Survival and Virulence Potential of Drug-Resistant E. coli in Simulated Gut Conditions and Antibiotic Challenge. International Journal of Environmental Research and Public Health. 2022 Oct 6;19(19):12805.
- Kotian A, Aditya V, Sheikh J, Saikrishnan S, Rai P, Chakraborty A, Karunasagar I, Deekshit VK. Effect of NaCl, high iron, iron chelator and antibiotics on growth, virulence gene expression and drug susceptibility in non-typhoidal Salmonella: an in vitro fitness study. Archives of Microbiology. 2022 Nov;204(11):1-9.
- Prabhakara AM, Nanjappa DP, Kotian A, Kalladka K, Chakraborty G, Vittal R, Raj JR, Deekshit VK, Chakraborty A. Wild-type and cancer-prone zebrafish exhibit distinct gut microbial diversity and differential anti-inflammatory response upon infection. Journal of Biosciences. 2022 Dec;47(4):1-10.
- Rani MS, Rohit A, V. Aditya, Shetty VP, Kotian A, Mohanapriya P, Rai P, Karunasagar I, Deekshit VK. Comparative analysis of different methods used for molecular characterization of Burkholderia cepacia complex isolated from noncystic fibrosis conditions. Indian Journal of Medical Microbiology. 2022, 40;74-80
- Aditya V, Kotian A, Saikrishnan S, Rohit A, Divyashree M, Karunasagar I, V K Deekshit. Effect of ciprofloxacin and in-vitro gut conditions on biofilm of Escherichia coli isolated from clinical and environmental sources. Journal of Applied Microbiology. 2022, 132 964-977.
- Jazeela, K., Chakraborty, A., Kotian, A., Aditya, V., Kumar, B.K., Rai, P., Karunasagar, I., Deekshit, V.K. (2021). Phenotypic characterization of auxotrophic mutant of nontyphoidal Salmonella and determination of its cytotoxicity, tumor inhibiting cytokine gene expression in cell line models. Archives of Microbiology, 203(6), 2925-2939.
- Caroline D'Souza, Prithvisagar K. S., Deekshit, V.K., Karunasagar, I., Karunasagar, I. and Kumar B. K. (2020) Exploring the Pathogenic Potential of Vibrio vulnificus Isolated from Seafood Harvested along the Mangaluru Coast, India. Microorganisms, 1-15.
- Akshatha, K., Aditya, V., Jazeela, K., Karunasagar, I., Karunasagar, I., Deekshit V.K., (2020) Effect of bile on growth and biofilm formation of multidrug resistant and sensitive non-typhoidal Salmonella serovars isolated from seafood and poultry. Research in Microbiology. 171;165-173.
- Jazeela, K., Chakraborty, A., Karunasagar, I., Deekshit, V.K. (2020). Nontyphoidal Salmonella: a potential anticancer agent. Journal of applied microbiology. 128(1):2-14.
- Deekshit, V.K., Jazeela, K., Chakraborty, G., Rohit, A., Chakraborty, A., Karunasagar, I. (2019) Mismatch amplification mutation assay-polymerase chain reaction: A method of detecting fluoroquinolone resistance mechanism in bacterial pathogens. Indian Journal of Medical Research.149(2):146-150.
Google Scholar: https://scholar.google.com/citations?user=u-H2oNsAAAAJ&hl=en
WoS: https://www.webofscience.com/wos/woscc/summary/4367c4db-6814-4477-a51f-59956e384aa6-685ac69e/relevance/1
Orcid ID: https://orcid.org/0000-0002-3535-5528
Patent Applied: 01
Temp/E-1/47842/2021-CHE (Filled on 20th September 2021). Consortium of Broad-spectrum jumbo bacteriophages for control of multidrug-resistant Pseudomonas aeruginosa by Rai, P., Kumar, B.K., Deekshit V.K., Juliet Mohan Raj (Applied)
• PhD students: 01 (Completed); 05 (ongoing)
• PG Students: 06 (completed), 01 (ongoing)
• UG Students: 05 (completed)
Undergraduate
Genetic Engineering & Biotechnology; Medical Biotechnology; Cell-Based Assay in Biomedical Science, Medical Microbiology
Postgraduate
Medical Microbiology, General Microbiology
Genetic Engineering & Biotechnology; Medical Biotechnology; Cell-Based Assay in Biomedical Science, Medical Microbiology
Postgraduate
Medical Microbiology, General Microbiology
Extramural
- Decoding the traits of drug resistance: Studying the genetic factors contributing to the survivability and adaptability of gut pathogens in antibiotic rich environment, funded by DST-SERB, 2018-2021 [Budget: 34.35 Lakhs]. (Completed)
- Investigating antimicrobial efficacy of NANOBIOTICS against multidrug resistant gut pathogens, funded by ICMR, 2021-2024 [Budget: 47 lakhs] (Ongoing).
- Deciphering outer membrane protein-based resistance of bacteria to antibiotics and bacteriophage for effective control of multidrug-resistant Acinetobacter baumannii, funded by ICMR, 2020-2023 [Budget: 25.56 lakhs] (Ongoing).
- Combating cancer through alternative approaches: Investigating the antitumor properties of non-typhoidal Salmonella in transgenic zebrafish cancer models, funded by ICMR, 2021-2024 [Budget: 52 lakhs] (Ongoing).
- Development and characterization of a novel three-dimensional Biofilm of Pseudomonas aeruginosa for the assessment of the mechanism of nonmucoid to mucoid strain conversion, virulence, antibiotic resistance and macrophage immune response ICMR, 2022-2025 [Budget: 32 lakhs] (Ongoing).
- Effect of bile on the invasion and replication of drug resistant gut pathogens in Caco-2 cell line, funded by NitteDU, 2019-2021 [Budget: 1.9 Lakhs]. (Ongoing)
- Quantification of thiamine levels and analysis of thiamine transporter gene in suspected Shoshin beriberi cases affecting a restricted population of Coastal Karnataka, funded by NitteDU, 2019-2021 [Budget:1.5 Lakhs] (Completed)
- Generation of transgenic zebrafish models for elucidating the molecular mechanism of Mycobacterium infection, funded by NitteDU, 2018-2020 [Budget: 1.6 Lakhs]. (Completed)
- Microorganisms as anticancer agents: Determination of antitumour activity of nontyphoidal Salmonella serovars funded by NitteDU, 2016-2019 [Budget:2.5 Lakhs] (Completed)
- Abstracts in national/ international conference: 12
- Nucleotide sequence submissions to NCBI GenBank: 40
- Expressed sequence tag sequence submissions: 3175
- Bacterial whole genome sequence submission:06
- Invited Talks /Oral Presentation (National/International): 05
- National / International workshops / conferences / symposium attended: 33
Dr. KRISHNA KUMAR BALLAMOOLE
- Designation Associate Professor G-I
- Email krishnakumarb@nitte.edu.in
- Contact No. .
- Joining date 16-08-2014
Dr. Krishna Kumar Ballamoole is a molecular microbiologist, obtained Ph.D. (Microbiology) from Manipal University. His research focuses on understanding and characterizing the genomic patterns that drives the evolution and infection capabilities of microbial pathogens of humans and animals. His work combines classical microbiological methods, molecular biology tool and next-generation sequencing strategies as fundamental tools to shed light on evolution, virulence capabilities and antibiotic resistance mechanisms in clinically relevant human and animal pathogens. In addition to pursuing the main research interest, the he is also involved in developing monoclonal antibody and nucleic acid based rapid diagnostics for the detection of pathogens.
- Doctor of Philosophy (Microbiology), Manipal University, Manipal, 2014
- Master of Science (Microbiology), Karnataka Veterinary, Animal and Fisheries Sciences University, 2009
- Assistant Professor - Grade-II, Nitte University Center for Science Education and Research, Mangaluru (2018-till date)
- Assistant Professor, Nitte University Center for Science Education and Research, Mangaluru (2014- 2018)
- Research Fellow, KVAFSU (2012-2014)
- Bacterial pathogenesis
- Antimicrobial Resistance
- Molecular diagnostics
- Recipient of collaborative Joint Research initiative of the "Tropical Medicine Research Center", Nagasaki University, Japan
- KSET - Karnataka State Eligibility Test, 2020-21
- Best Research Paper Award, NitteDU, 2019
- Indo-Japanese Young Research Fellow, Research Institute for Microbial Diseases, Osaka University, Japan, 2019
- Early Career Research Award, DST-SERB, Govt. of India, 2017.
- EMBO short term Bfellowship, Ben Gurion University of the Negev, Israel, 2017
- Japan-Asia Youth Exchange program in Science (SAKURA exchange) awardee, 2015
- Invited talk at International Conference of Sabaragamuwa University of Sri Lanka, 2015
- Member Secretary, Intuitional Ethics Committee
- Member, Student Welfare Committee
- Coordinator, NueLearn 2020-21, NUCSER
- Member, International Society of Infectious Diseases, USA
- Life Member, Society of Biological Chemists, India
- Life Member, Association of Microbiologists of India (AMI), India
- Member, Professional Fisheries Graduates' Forum (PFGF), India
- Member, College of Fisheries Alumni Association, Mangalore, India
Selected Journal publications:
Google scholar ID: https://scholar.google.co.in/citations?user=KpRyzTYAAAAJ&hl=en
ResearchGate: https://www.researchgate.net/profile/Ballamoole-Kumar
Web of Science: https://publons.com/researcher/4048767/ballamoole-krishna-kumar/
Orcid ID: https://orcid.org/0000-0001-7821-7419
Patent filed: 02
- Prithvisagar, K. S., Krishna Kumar, B., Kodama, T., Rai, P., Iida, T., Karunasagar, I., & Karunasagar, I. (2021). Whole genome analysis unveils genetic diversity and potential virulence determinants in Vibrio parahaemolyticus associated with disease outbreak among cultured Litopenaeus vannamei (Pacific white shrimp) in India. Virulence, 12(1), 1936-1949
- Rai, P., Kille, S., Kotian, A., Kumar, B. K., Deekshit, V. K., Ramakrishna, M. S., ... & Karunasagar, I. (2021). Molecular investigation of the dengue outbreak in Karnataka, South India, reveals co-circulation of all four dengue virus serotypes. Infection, Genetics and Evolution, 92, 104880
- D'Souza, C., Prithvisagar, K. S., Deekshit, V. K., Karunasagar, I., Karunasagar, I., & Kumar, B. K. (2020). Exploring the Pathogenic Potential of Vibrio vulnificus Isolated from Seafood Harvested along the Mangaluru Coast, India. Microorganisms, 8(7), 999
- Rajesh, M.K., Muralikrishna, K.S., Nair, S.S., Kumar, B.K., Subrahmanya, T.M., Sonu, K.P., Subaharan, K., Sweta, H., Prasad, T.K., Chandran, N., Karunasagar, I. (2020) Facile coconut inflorescence sap mediated synthesis of silver nanoparticles and its diverse antimicrobial and cytotoxic properties. Materials Science and Engineering: C 111: 110834
- D'Souza, C., Kumar, B.K., Rai, P., Deekshit, V.K., Karunasagar, I. (2019). Application of gyrB targeted SYBR green based qPCR assay for the specific and rapid detection of Vibrio vulnificus in seafood. Journal of Microbiological Methods 166:105747
- Rohit, A., Kumar, D.S., Dhinakaran, I., Joy, J., Kumar, D.V., Kumar, B.K., Karunasagar, I., Karola, P. and Dag, H. (2019) Whole-genome-based analysis reveals multiclone Serratia marcescens outbreaks in a non-Neonatal Intensive Care Unit setting in a tertiary care hospital in India. Journal of Medical Microbiology 68: 616-621
- D'Souza, C., Kumar, B.K., Kapinakadu, S., Shetty, R., Karunasagar, I., Karunasagar, I. (2018) PCR-based evidence showing the presence of Vibrio vulnificus in wound infection cases in Mangaluru, India. International Journal of Infectious Diseases 68:74-76
- Deekshit, V.K., Kumar, B.K., Rai, P., Karunasagar, I., Karunasagar, I. (2015) Differential expression of virulence genes and role of gyrA mutations in quinolone resistant and susceptible strains of Salmonella Weltevreden and Newport isolated from seafood. Journal of Applied Microbiology 119:970-980
- Kumar, B.K., Deekshit, V.K., Raj, J.R.M., Rai, P., Shivanagowda, B.M., Karunasagar, I., Karunasagar, I. (2014) Diversity of Vibrio parahaemolyticus associated with disease outbreak among cultured Litopenaeus vannamei (Pacific white shrimp) in India. Aquaculture 433:247-251
- Kumar, B.K., Deekshit, V.K., Rai, P., Shekar, M., Karunasagar, I., Karunasagar, I. (2014) Presence of T3SS2β genes in trh+ Vibrio parahaemolyticus isolated from seafood harvested along Mangalore coast, India. Letters in Applied Microbiology 58:440-446
- Kumar, B.K., Raghunath, P., Devegowda, D., Deekshit, V.K., Venugopal, M.N., Karunasagar, I., & Karunasagar, I. (2011) Development of monoclonal antibody-based sandwich ELISA for the rapid detection of pathogenic Vibrio parahaemolyticus in seafood. International Journal of Food Microbiology 145:244-249
Google scholar ID: https://scholar.google.co.in/citations?user=KpRyzTYAAAAJ&hl=en
ResearchGate: https://www.researchgate.net/profile/Ballamoole-Kumar
Web of Science: https://publons.com/researcher/4048767/ballamoole-krishna-kumar/
Orcid ID: https://orcid.org/0000-0001-7821-7419
Patent filed: 02
Journal publications:
Google scholar ID: https://scholar.google.co.in/citations?user=KpRyzTYAAAAJ&hl=en
Research Gate: https://www.researchgate.net/profile/Ballamoole-Kumar
Web of Science Researcher ID: https://publons.com/researcher/4048767/ballamoole-krishna-kumar/
Orcid ID: https://orcid.org/0000-0001-7821-7419
Patents
- Pinto, D. S., Prithvisagar, K. S., Rohit, A., Karunasagar, I., Karunasagar, I., & Kumar, B. K. (2022). Genome analysis of clinical isolate of Campylobacter fetus subspecies fetus MMM01 from India reveals genetic determinants of pathogenesis and adaptation. Acta Microbiologica et Immunologica Hungarica. (In Press)
- Prithvisagar, K. S., Krishna Kumar, B., Kodama, T., Rai, P., Iida, T., Karunasagar, I., & Karunasagar, I. (2021). Whole genome analysis unveils genetic diversity and potential virulence determinants in Vibrio parahaemolyticus associated with disease outbreak among cultured Litopenaeus vannamei (Pacific white shrimp) in India. Virulence, 12(1), 1936-1949.
- Rai, P., Kille, S., Kotian, A., Kumar, B. K., Deekshit, V. K., Ramakrishna, M. S., ... & Karunasagar, I. (2021). Molecular investigation of the dengue outbreak in Karnataka, South India, reveals co-circulation of all four dengue virus serotypes. Infection, Genetics and Evolution, 92, 104880.
- D'Souza, C., Prithvisagar, K. S., Deekshit, V. K., Karunasagar, I., Karunasagar, I., & Kumar, B. K. (2020). Exploring the Pathogenic Potential of Vibrio vulnificus Isolated from Seafood Harvested along the Mangaluru Coast, India. Microorganisms, 8(7), 999.
- D'Souza, C., Kumar, B.K., Rai, P., Deekshit, V.K., Karunasagar, I. (2019). Application of gyrB targeted SYBR green based qPCR assay for the specific and rapid detection of Vibrio vulnificus in seafood. Journal of Microbiological Methods 166:105747.
- Rohit, A., Kumar, D.S., Dhinakaran, I., Joy, J., Kumar, D.V., Kumar, B.K., Karunasagar, I., Karola, P. and Dag, H. (2019) Whole-genome-based analysis reveals multiclone Serratia marcescens outbreaks in a non-Neonatal Intensive Care Unit setting in a tertiary care hospital in India. Journal of Medical Microbiology 68: 616-621.
- D'Souza, C., Kumar, B.K., Kapinakadu, S., Shetty, R., Karunasagar, I., Karunasagar, I. (2018) PCR-based evidence showing the presence of Vibrio vulnificus in wound infection cases in Mangaluru, India. International Journal of Infectious Diseases 68:74-76.
- Kumar, B.K., Deekshit, V.K., Raj, J.R.M., Rai, P., Shivanagowda, B.M., Karunasagar, I., Karunasagar, I. (2014) Diversity of Vibrio parahaemolyticus associated with disease outbreak among cultured Litopenaeus vannamei (Pacific white shrimp) in India. Aquaculture 433:247-251.
- Kumar, B.K., Deekshit, V.K., Rai, P., Shekar, M., Karunasagar, I., Karunasagar, I. (2014) Presence of T3SS2β genes in trh+ Vibrio parahaemolyticus isolated from seafood harvested along Mangalore coast, India. Letters in Applied Microbiology 58:440-446.
- Kumar, B.K., Raghunath, P., Devegowda, D., Deekshit, V.K., Venugopal, M.N., Karunasagar, I., & Karunasagar, I. (2011) Development of monoclonal antibody-based sandwich ELISA for the rapid detection of pathogenic Vibrio parahaemolyticus in seafood. International Journal of Food Microbiology 145:244-249.
Google scholar ID: https://scholar.google.co.in/citations?user=KpRyzTYAAAAJ&hl=en
Research Gate: https://www.researchgate.net/profile/Ballamoole-Kumar
Web of Science Researcher ID: https://publons.com/researcher/4048767/ballamoole-krishna-kumar/
Orcid ID: https://orcid.org/0000-0001-7821-7419
Patents
- Temp/E-1/31373/2021-CHE (Filled on 22nd June 2021). Unique primers for rapid detection test for SARS CoV-2 using loop-mediated isothermal amplification by Maiti, B., Rai, P., Anupama, K.P., Kumar, B.K. (Published)
- Temp/E-1/47842/2021-CHE (Filled on 20th September 2021). Consortium of Broad-spectrum jumbo bacteriophages for control of multidrug resistant Pseudomonas
PhD students: 02 (Completed); 05 (ongoing)
PG Students: 07 (completed)
UG Students: 05 (completed); Other students: 01
Undergraduate:
Postgraduate:
- Fundamentals of Immunology
- Food and Nutrition
Postgraduate:
- Immunology; Fish Immunology and Health Management; Molecular
- Diagnostics; Food Chemistry; Food Toxicology
Ongoing:
As PI:
As PI:
As PI:
- Elucidation of platelet activation and NLRP-3 inflammasome response in platelets during invasive Vibrio vulnificus infection to understand its potential role in the immunopathogenesis, funded by ICMR, Govt of India, 2022-2025 Budget: [27.62 lakhs]
- Pathogenomic and functional analysis to unravel the pathogenic potential of epidemic strains of Vibrio parahaemolyticus from environmental sources, funded by the Institute of Tropical Medicine, Nagasaki University, Japan, 2022-23 Budget: [600,000 yen]
- Development of immunofluorescent nanodiagnostic assay as a point-of-care detection of dengue virus, Funded by DST-BDTD, 2021-2023 [Budget: 21.86 lakhs]
- DST-Technology Enabling Centre (TEC), funded by DST, 2019-2024.
- Development of monoclonal antibody against NS1 and E proteins of dengue virus, Funded by Nitte (DU), 2019-2021 [Budget: 1.9 lakhs].
- Antiviral properties of four medicinal plant extracts against dengue virus, Funded by Nitte (DU), 2018-2020 [Budget: 1.6 lakhs].
As PI:
- Exploring the distribution and characterization of pathogenicity islands and ecological fitness genes in seafood associated Vibrio parahaemolyticus, funded by DST-SERB, 2018-2021 [26.66 lakhs]
- Tracing the molecular epidemiology of Leptospirosis and assessing its zoonotic transmission potential in Dakshina Kannada District, Karnataka, Funded by Nitte (DU), 2019-2021 [Budget: 1.9 lakhs].
- Development of rapid point of care assay for the sensitive detection of Vibrio vulnificus; Funded by NitteDU, 2018-2020 [Budget: 2.5 lakhs]
- Effect of carbohydrate on quorum sensing mediated pathogenicity in Pseudomonas aeruginosa; Funded by NitteDU, 2018-2020 [Budget: 1.7 lakhs]
- Abstracts in national/ international conference: 10
- Nucleotide sequence submissions to NCBI GenBank: 50
- Expressed sequence tag sequence submissions: 3500
- Whole genome sequence (Bacteria/Viruses/Bacteriophages) submission:10
- Invited Talks /Oral Presentation (National/International): 04
- National / International workshops / conferences / symposium attended: 30
Dr. ANURAG SHARMA
- Designation Associate Professor-Grade I
- Email anuragsharma@nitte.edu.in
- Contact No. .
- Joining date 17-05-2016
Anurag Sharm is working as Assistant Professor at NUCSER, Nitte University. During his Ph.D. he studied the stress response of endosulfan on D. melanogaster, a non-target organism, at sub-organismal as well as organismal level. Further, his studies also highlight the potential of D. melanogaster as an alternative animal model for in-vivo assessment of environmental chemical mediated toxicity, which might have relevance to higher organisms. Later, he joined CNRS-Centre de Biologie du Développement, Toulouse, France as a postdoctoral researcher and worked on deciphering the function of the Drosophila hematopoietic niche to maintain blood cell homeostasis. Presently, he is engaged in the following areas-a) Development of an in vivo Drosophila model to study toxicant/radiation induced hematopoietic perturbations and b) Host-Microbe interaction and environmental toxicants.
Doctor of Philosophy (Cellular and Molecular toxicology), CSIR-IITR Lucknow and Jamia Hamdard, 2012
Master of Science (Biotechnology), Jiwaji University, 2005
- Associate Professor, Nitte University Centre for Science Education and Research (August 2022-till date)
- Assistant Professor, Nitte University Centre for Science Education and Research (May 2016- August 2022)
- Postdoctoral Fellow (Developmental Biology), Centre de Biologie du Développement (CBD), Toulouse, France (2012 - 2016)
Cellular and Molecular toxicology
Cellular immune response
Cellular and molecular stress response
DST-SERB Young scientist start-up grant award, 2017
Japan-Asia Youth Exchange program in Science (SAKURA exchange) awardee, 2018
In-charge, Lab Resource Committee, NUCSER
Member Secretary, Institutional committee against sexual harassment, NUCSER
Member, Institutional committee against substance abuse, NUCSER
- Paithankar JG, Gupta SC, Sharma A. Therapeutic potential of low dose ionizing radiation against cancer, dementia, and diabetes: evidences from epidemiological, clinical, and preclinical studies. Molecular Biology Reports. 2023 Jan 3:1-2.
- Vimal D, D'Souza LC, Rai V, Lal S, Sharma A*, Gupta SC*. Efficacy of cannabis and its constituents in disease management: Insights from clinical studies. Current Medicinal Chemistry. 2023 Jan; 30(2):178 -202. *Corresponding author
- D'Souza LC, Kuriakose N, Raghu SV, Kabekkodu SP, Sharma A. ROS-directed activation of Toll/NF-κB in the hematopoietic niche triggers benzene-induced emergency hematopoiesis. Free Radical Biology and Medicine. 2022 Nov 20;193:190-201.
- Kushalan S, D'Souza LC, Aloysius K, Sharma A*, Hegde S*. Toxicity Assessment of Curculigo orchioides Leaf Extract Using Drosophila melanogaster: A Preliminary Study. International Journal of Environmental Research and Public Health. 2022 Nov 18;19(22):15218. *Corresponding author
- D'Souza LC, Shekher A, Challagundla KB, Sharma A*, Gupta SC*. Reprogramming of glycolysis by chemical carcinogens during tumor development.Seminars in Cancer Biology 2022 Dec;87:127-136 . *Corresponding author
- D'Souza LC, Dwivedi S, Raihan F, Yathisha UG, Raghu SV, Mamatha BS, Sharma A. Hsp70 overexpression in Drosophila hemocytes attenuates benzene‐induced immune and developmental toxicity via regulating ROS/JNK signaling pathway. Environmental Toxicology. 2022 Jul;37(7):1723-1739.
- Paithankar JG, Kushalan, S, Nijil, S, Hegde, S, Kini, S*, Sharma A* (2022) Systematic toxicity assessment of CdTe quantum dots in Drosophila melanogaster. Chemosphere. 1;295:133836. *Corresponding author
- Diwivedi S, D'Souza LC, Shetty NG, Raghu, SV, Sharma A* (2022) Hsp27, a potential EcR target, protects nonylphenol-induced cellular and organismal toxicity in Drosophila melanogaster. Environmental Pollution 293: 118484.
- Dwivedi S, Kushalan S, Paithankar JG, D'Souza LC, Hegde S, Sharma A. Environmental toxicants, oxidative stress and health adversities: interventions of phytochemicals. Journal of Pharmacy and Pharmacology. 2022 Apr;74(4):516-36.
- Paithankar JG, Saini S, Dwivedi S, Sharma A*, Chowdhuri DK*(2021) Heavy metal associated health hazards: An interplay of oxidative stress and signal transduction. Chemosphere 262:128350. *Corresponding author
- D'Souza LC, Mishra S, Chakraborty A, Shekher A, Sharma A*, Gupta SC* (2020) Oxidative stress and cancer development: Are non-coding RNAs the missing links? Antioxidants & Redox Signaling 10;33(17):1209-1229. *Corresponding author
- Louradour I, Sharma A, Morin-Poulard I, Letourneau M, Vincent A, Vanzo N, Crozatier M (2017). Reactive oxygen species-dependent Toll/NF-κB activation in the Drosophila hematopoietic niche confers resistance to wasp parasitism. Elife doi: 10.7554/eLife.25496.
- Letourneau M, Lapraz F, Sharma A, Vanzo N, Waltzer L, Crozatier M (2016). Drosophila hematopoiesis under normal conditions and in response to immune stress. FEBS Letters 590: 4034-4051.
- Morin-Poulard I, Sharma A, Louradour I, Vanzo N, Vincent A, Crozatier M (2016). Vascular control of the Drosophila hematopoietic niche: role of Slit/Robo signaling. Nature Communications 11634.
- Sharma A, M Mishra, AK Shukla, R Kumar, MZ Abdin, Chowdhuri DK (2012). Organochlorine pesticide, endosulfan induced cellular and organismal response in Drosophila melanogaster. Journal of Hazardous Materials 221-222, 275-287.
- Sharma A, Mishra M, Ravi Ram K, Kumar R, Abdin MZ, Chowdhuri DK (2011). Transcriptome analysis provides insights for understanding the adverse effects of endosulfan in Drosophila melanogaster. Chemosphere 82: 370-376.
- Sharma A, Mishra M, Shukla AK, Chowdhuri DK (2011). Validation and application of Drosophila melanogaster as an in vivo model for the detection of double strand breaks by neutral Comet assay. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 721: 142-146.
- Souza LC, Paithankar JG, Siddique HR, Sharma A (2021) Future of herbal medicines in assisted reproduction. In: Herbal Medicines, A Boon for Healthy Human Life. Siddique H, Sarwat M (eds), 1st Edition. Elsevier Academic Press, ISBN: 9780323906999
- Saini S, Paithankar JG, Sharma A, Chowdhuri DK. (2021) Environmental Toxicants and Carcinogenicity: Role of Oxidative Stress. In Handbook of Oxidative Stress and Cancer. S. Chakraborti et al. (eds.). Springer Nature Singapore, in press
- Awasthee N, Shekher A, Rai V, Baruah PK, Sharma A, Challagundla KB, Gupta SC (2021). Clinical significance of long non-coding RNAs in breast cancer patients. In: Clinical applications of non-coding RNAs in cancer. Gupta SC, Challagundla KB (eds). Elsevier Inc Cambridge, MA, USA, 2021, ISBN: 9780128245507
- Chaouhan HS, Rai, Kini, S, Shekher A, Sharma A, Gupta SC. (2021) Potential of Long Non-coding RNAs in the Diagnosis and Therapy of Melanoma Skin Cancer. In: Skin Cancer: Pathogenesis and Diagnosis. Dwivedi A., Tripathi A., Ray R.S., Singh A.K. (eds). Springer, Singapore. ISBN: 9811603634
- Kini S, Badekila AK, Barh D, Sharma A. (2020) Cellular and Organismal Toxicity of Nanoparticles and Its Associated Health Concerns. In: NanoBioMedicine. Saxena S., Khurana S. (eds). Springer, Singapore. ISBN: 9789813298972
- Sharma A, D'Souza C, Rai V, Gupta SC. (2019) Evaluation of Safety and Efficacy of Nutraceuticals Using Drosophila as an in Vivo Tool. In: Nutraceuticals in Veterinary Medicine. Gupta R, Srivastava A, Lall R. (eds) Springer, Cham. ISBN 9783030046248.
- Gupta SC, Sharma A, Mishra S, Awasthee N. (2019) Nutraceuticals for the Prevention and Cure of Cancer. In: Nutraceuticals in Veterinary Medicine. Gupta R., Srivastava A., Lall R. (eds). Springer, Cham. ISBN 9783030046248.
- Dwivedi S, Verma S, D'Souza, C, Awasthee, N, Sharma A, Gupta SC. (2019) Potential of Small Animals in Toxicity Testing: Hope from Small World. In: Biomarkers in Toxicology. Ramesh C.Gupta (eds) 2nd Edition. Elsevier Academic Press. ISBN: 9780128146569.
Google Scholar: https://scholar.google.fr/citations?user=-TpHINkAAAAJ&hl=en
PhD students: 03 (ongoing)
CSIR-RA: 01 (completed)
PG students: 07 (completed)
Undergraduate-
Principles of Pharmacology and Toxicology, Cancer Biology, Cell Based Assays in Biomedical Research, Methods in Ecotoxicology
Postgraduate-
Toxicology, Cell and Molecular Biology
Research projects
Extramural Funding
Extramural Funding
- Decoding the molecular mechanism associated with ionizing radiation induced hematopoietic malignancy using Drosophila model system, funded by ICMR , 2022-2024.
- Deciphering the molecular mechanisms involved in hematopoietic perturbation induced by environmental chemical(s) using Drosophila as an animal model, funded by DST-SERB, 2017-2020.
- Elucidating the host-microbiome association in toxicant exposed Drosophila melanogaster
- Niche cues for stress hematopoiesis: insights from Drosophila
DR. VIVEK TRIPATHI
- Designation Associate Professor - (G-I)
- Email vivek.tripathi@nitte.edu.in
- Contact No. 05-01-2023
- Joining date 05-01-2023
Dr. Vivek completed his Ph.D. (Molecular & Cell Biology) from Institut de Genetique et de Biologie Moleculaire et Cellulaire (IGBMC), Strasbourg Université, France. He has worked as a DBT research associate at National Institute of Immunology (NII), New Delhi India. He did his post-doc at Erasmus University Medical Center (Erasmus MC), Rotterdam, The Netherlands. His research focus includes replication stress mediated DNA damage response and tumorigenesis. Further, he discovered a molecular mechanism underlying the oscillation between sensitivity and resistance to FDA-approved PARP inhibitor drugs for BRCA1- and BRCA2 mutated breast cancer cells with important implications for treatment strategies and patient outcomes. His research interest includes identifying the novel druggable molecular targets associated with SUMOylation/Ubiquitylation cellular pathways and discovering their potential roles in the modulation of replication fork dynamics and genome stability. Thereafter, determine their anticancer efficacy by employing advanced experimental techniques to develop combined therapies which would involve increasing their sensitivity to existing therapeutic drugs for the treatments of cancer patients in the clinics.
• Master in Biotechnology, Université Louis Pasteur (ULP), Illkirch, France, 2008
• Doctor of Philosophy (Molecular & Cell Biology), (IGBMC), Strasbourg Université, France, 2012
• Doctor of Philosophy (Molecular & Cell Biology), (IGBMC), Strasbourg Université, France, 2012
• Associate Professor G-I, Nitte University Centre for Science Education and Research (NUCSER) (2023-till date)
• Post-doc, Department of Molecular Genetics, Erasmus University Medical Center (Erasmus MC), Rotterdam, The Netherlands (2018- 2022)
• DBT- Research Associate, Department of Genetics, Cell Signalling & Cancer Biology, National Institute of Immunology (NII), New Delhi, India (2013-2018)
• Post-doc, Department of Molecular Genetics, Erasmus University Medical Center (Erasmus MC), Rotterdam, The Netherlands (2018- 2022)
• DBT- Research Associate, Department of Genetics, Cell Signalling & Cancer Biology, National Institute of Immunology (NII), New Delhi, India (2013-2018)
• Replication Stress and DNA damage
• Fork Stabilization and Genome Stability
• Molecular Biology & Chemoresistance
• Fork Stabilization and Genome Stability
• Molecular Biology & Chemoresistance
Member, Academic Committee, NUCSER
Selected Publications
Google Scholar: https://scholar.google.com/citations?user=tt_F5OgAAAAJ&hl=en
Orcid ID: https://orcid.org/my-orcid?orcid=0000-0002-4453-0105
- Dias M P. *, Tripathi V. *, Heijden I V D., Cong K., Manolika E M., Bhin J., Gogola E., Galanos P., Annunziato S., Lieftink C., Sanchez M A., Chakrabarty S., Smith G C M., Ven M V D., Beijersbergen R L., Bartkova J., Rottenberg S., Cantor S., Bartek J., Ray Chaudhuri A. #, Jonkers J. # (2021). Loss of Nuclear DNA ligase III Can Revert PARP Inhibitor Resistance in BRCA1/53BP1 Double- deficient Cells by Exposing ssDNA Gaps. Molecular Cell 81 (22), 4692-4708. [*Equal contribution], [#Co-corresponding author]
- Tripathi V., Kaur E., Kharat S S., Hussain M., Damodaran A P., Kulshrestha S., Sengupta S. (2019). Abrogation of FBW7α-dependent p53 degradation enhances p53's function as a tumor suppressor. Journal of Biological Chemistry, doi:294 (36):13224-13232.
- Mukherjee C., Tripathi V., Manolika E M., Heijink A M., Ricci G., Merzouk S., Boer H R D., Demmers J., van Vugt M A T M., Ray Chaudhuri A. (2019). RIF1 promotes replication fork protection and efficient restart to maintain genome stability. Nature Communications, doi:10.1038/s41467-019-11246-1.
- Priyadarshini R., Hussain M., Attri A., Kaur E., Tripathi V., Priya S., Dhapola P., Saha D., Madhavan V., Chowdhury S., Sengupta S. (2018). BLM Potentiates c-Jun Degradation and Alters Its Function as an Oncogenic Transcription Factor. Cell Reports, 24(4):947-961.e947.
- Tripathi V., Agarwal H., Priya S., Batra H., Modi P., Pandey M., Saha D., Raghavan S C., and Sengupta S. (2018). MRN complex-dependent recruitment of ubiquitylated BLM helicase to double-strand breaks negatively regulates DNA repair pathways. Nature Communications, 9(1), 1016.
Google Scholar: https://scholar.google.com/citations?user=tt_F5OgAAAAJ&hl=en
Orcid ID: https://orcid.org/my-orcid?orcid=0000-0002-4453-0105
PhD students: 01 (ongoing), UG students: 02 (completed)
Undergraduate: Clinical Genetics
Dr. RAMA ADIGA
- Designation Assistant Professor
- Email rama_adiga@nitte.edu.in
- Contact No. .
- Joining date 01-08-2013
With more than 15 years of experience in research and teaching, she has attended several conferences and been resource person at National and International level. Her latest visit to the U.S.A where she was invited as speaker to present a research paper on Zika virus at the First International Conference on Zika Virus 2017 held at Washington D.C, 2017. Her major research areas include Parasitology with special interest in Malaria in the city of Mangaluru where drug resistance is beginning to appear. She is presently working in the division of Bioinformatics and Computational genomics with increased surveillance and research on various viruses spreading across the globe.
Doctor of Philosophy (Bioscience), Mangalore University, 2012
Master of Science (Biochemistry), Nagpur University, 1988
Diploma Post Graduate Diploma in Advanced Bioinformatics
Bioinformatics Institute of India, Noida, 2005
IBM Advanced Career Education: Web Programming, 2002
IBM Advanced Certificate Course: Oracle 8i, 2002
Assistant Professor, Nitte University Center for Science Education and Research, Mangaluru (2013- till date)
Project Assistant, College of Fisheries, Mangaluru (2006-2013)
Molecular characterization of malarial plasmodium
Malaria and Antimicrobial Resistance
Molecular Biology
Bioinformatics
Sequencing and bioinformatics
Appreciation award from NitteDU for participation in National Integration Camp, 2020
Invited speaker at First International Conference on Zika virus, Washington D.C, U.S.A, 2017
Best Poster Award, Eighth symposium on Diseases in Asian Aquaculture, Mangalore, 2011
Associate Editor, International Journal of Biosensors and Bioelectronics , 2016
Elsevier Outstanding Reviewer Award , 2018
Member, Board of Studies in Biological Sciences (UG and PG), Nitte DU
Member, Lab Vigilance Committee, NUCSER
Program Officer-NSS, NUCSER
Life member, Society for Biological Chemists
Journal publications
- Adiga R (2021). Benchmarking Datasets from Malaria Cytotoxic T-cell Epitopes Using Machine Learning Approach. Avicenna Journal of Medical Biotechnology 13:87-91.
- Rama Adiga, Jyothi Bhatkal (2021). In Silico study of gene expression changes in prostate cancer due to endocrine-disrupting chemicals. Research Journal of Chemistry and Environment.25:1-4
- Adiga, R. (2019). Molecular Docking of Hyrtimomine A-K from marine sponge Hyrtios spp. as anti-cancer target of Phosphoinositide-dependent kinase 1. Asian Journal of Pharmaceutical and Clinical Research 12:130-135.
- Adiga, R. (2019). Emergence of Nipah Virus: A Review. Journal of Biomedical and Pharmaceutical Research 8:48-54
- Adiga, R. (2016). Phylogenetic analysis of the NS5 gene of Zika virus. Journal of Medical Virology 88:1821-1826.
- Adiga, R., Karunasagar, I. (2015) In silico approaches to drug discovery. International Journal of Advanced Research 3:1522-1528.
- Adiga, R., Adiga R. (2015). Bioinformatics based analysis of microarrays in human bipolar disorder. International Journal of Innovative Research in Computer and Communication Engineering 3: 261-266.
Conference publications- 8
• PhD student :01 (ongoing)
• PG student: 03 (completed), 02 ongoing
• UG students: 02 (completed), 02 ongoing
Undergraduate-
Clinical Biochemistry, General Biochemistry, Introductory Bioinformatics
Postgraduate-
Bioinformatics and Computational Biology, Medical Biochemistry, Food Chemistry
• PhD student :01 (ongoing)
• PG student: 03 (completed), 02 ongoing
• UG students: 02 (completed), 02 ongoing
• PG student: 03 (completed), 02 ongoing
• UG students: 02 (completed), 02 ongoing
Currently guiding Ph.D. student, working on the malaria problem in south-west India
Dr. RAMYA HARSHA
- Designation Assistant Professor
- Email ramya@nitte.edu.in
- Contact No. .
- Joining date 01-02-2013
Dr. Ramya Harsha is an Assistant Professor at NUCSER. She has obtained her Ph.D. degree from Department of Microbiology, University of Mysore in the year 2012. She joined NUCSER in 2013. Her research interests include virulence in bacterial pathogens, quorum sensing and isolation of anti-quorum sensing molecules from phytal sources and attenuation of quorum sensing in bacteria. She has secured second rank in MSc Microbiology from University of Mysore.
- Doctor of Philosophy (Microbiology), University of Mysore, 2012
- Master of Science (Microbiology), University of Mysore, 2000
- Assistant Professor, Nitte Centre for science education and research, Mangaluru (2013 – till date)
- Guest faculty, Dept. of Microbiology, University of Mysore (2006 - 2011)
- Infectious Disease Biology (Bacteriology)
- Virulence mechanisms of pathogens
- Bacterial quorum sensing
- Isolation and identification of anti-quorum sensing molecules
- Microplastics
Sakura Science Fellowship administered by Japan Science & Technology, 2018
- Coordinator IQAC, NUCSER
- Coordinator AISHE, NUCSER
- Coordinator, NUeLearn, NUCSER
- Member secretary, Institutional-Anti-Ragging Committee, NUCSER
- In charge of Hostel committee, NUCSER
- Member, I-CASA, NUCSER
- Member, COVID-19 task force, NUCSER
- Member, Institutional committee for the development of professional competence in teaching, NUCSER
- Life Member, Association of Microbiologists of India
- Member, Society of Biological Chemists, India
Selected Journal Publications:
- Scholtz, V., Vanková, E., Kašparová, P., Premanath, R., Karunasagar, I., Julák, J. (2021) Non-thermal plasma treatment of ESKAPE pathogens: a review. Frontiers in Microbiology 12:737635
- Prathiksha, P.A., Sarika, S., Dechamma, P.N., Jainey, P.J., Rajesh, K., Anirban, C., Sarojini, B.S., Premanath, R. (2021) Isolation and identification of quorum sensing antagonist from Cinnamomum verum leaves against Pseudomonas aeruginosa. Life Sciences 267:118878.
- Sarika, S., Prathiksha, P.A., Premanath, R. (2021) Modulation of quorum sensing-associated virulence in bacteria: carbohydrate as a key factor. Archives of Microbiology 203: 1881-1890.
- Prathiksha, P. A., Shraddha S., Caroline D'Souza, Premanath, R. (2021) Increased expression of genes involved in biofilm formation in a multidrug‑resistant environmental Pseudomonas aeruginosa isolate. Journal of Datta Meghe Institute of Medical Sciences University. 2021; 10.4103/jdmimsu.jdmimsu_286_20.
- Prathiksha, P.A., Sarika, S., Gururaj, M.P., Premanath, R. (2019) Evaluation of anti-quorum sensing activity of indigenous dietary plants against Pseudomonas aeruginosa. European Journal of Integrative Medicine 30: 100931.
- Sarika, S., Prathiksha, P.A., Akash, S.K., Premanath, R. (2019) Biofilm Forming Abilities of Microorganisms Associated with Diabetic Wound Infection: A Study from a Tertiary Care Hospital. Biomedical & Pharmacology Journal 12(2): 669-676.
- Sarika, S., Anupama, K. P., Prathiksha, P.A., Akash, S.K., Maiti, B., Karunasgar, I., Karunasagar, I., Premanath, R. (2019) Diabetic foot ulcer caused by Vibrio parahaemolyticus - Two case reports. Clinical Microbiology Newsletter 41: 101-102.
- Prathiksha, P.A., Prasad, R., Venkatesh, T., Suresh, P.S., Premanath, R. (2019) Increased virulence in Pseudomonas aeruginosa at pathological glucose levels. Infectious diseases 51: 153-156.
- Prathiksha, P.A., Juliet, M.R., Karunasagar, I., Premanath R. (2018) Environmental and clinical Pseudomonas aeruginosa isolates with pooled presence of exo S, exo U, exo T and exo Y genes. Journal of Pure and Applied Microbiology 12: 1119-1124.
- Premanath, R., Lakshmidevi, N. (2015) Antidiabetic and Antioxidant potential of Andrographis paniculata Nees. leaf ethanol extract in streptozotocin induced diabetic rats. Journal of Applied Pharmaceutical Science 5: 69-76.
Selected Journal Publications
- Scholtz, V., Vanková, E., Kašparová, P., Premanath, R., Karunasagar, I., Julák, J. (2021) Non-thermal plasma treatment of ESKAPE pathogens: a review. Frontiers in Microbiology 12:737635
- Prathiksha, P.A., Sarika, S., Dechamma, P.N., Jainey, P.J., Rajesh, K., Anirban, C., Sarojini, B.S., Premanath, R. (2021) Isolation and identification of quorum sensing antagonist from Cinnamomum verum leaves against Pseudomonas aeruginosa. Life Sciences 267:118878
- Sarika, S., Prathiksha, P.A., Premanath, R. (2021) Modulation of quorum sensing-associated virulence in bacteria: carbohydrate as a key factor. Archives of Microbiology 203: 1881-1890
- Prathiksha, P. A., Shraddha S., Caroline D'Souza, Premanath, R. (2021) Increased expression of genes involved in biofilm formation in a multidrug‑resistant environmental Pseudomonas aeruginosa isolate. Journal of Datta Meghe Institute of Medical Sciences University. 2021; 10.4103/jdmimsu.jdmimsu_286_20
- Prathiksha, P.A., Sarika, S., Gururaj, M.P., Premanath, R. (2019) Evaluation of anti-quorum sensing activity of indigenous dietary plants against Pseudomonas aeruginosa. European Journal of Integrative Medicine 30: 100931
- Sarika, S., Prathiksha, P.A., Akash, S.K., Premanath, R. (2019) Biofilm Forming Abilities of Microorganisms Associated with Diabetic Wound Infection: A Study from a Tertiary Care Hospital. Biomedical & Pharmacology Journal 12(2): 669-676
- Sarika, S., Anupama, K. P., Prathiksha, P.A., Akash, S.K., Maiti, B., Karunasgar, I., Karunasagar, I., Premanath, R. (2019) Diabetic foot ulcer caused by Vibrio parahaemolyticus - Two case reports. Clinical Microbiology Newsletter 41: 101-102
- Prathiksha, P.A., Prasad, R., Venkatesh, T., Suresh, P.S., Premanath, R. (2019) Increased virulence in Pseudomonas aeruginosa at pathological glucose levels. Infectious diseases 51: 153-156
- Prathiksha, P.A., Juliet, M.R., Karunasagar, I., Premanath R. (2018) Environmental and clinical Pseudomonas aeruginosa isolates with pooled presence of exo S, exo U, exo T and exo Y genes. Journal of Pure and Applied Microbiology 12: 1119-1124
- Premanath, R., Lakshmidevi, N. (2015) Antidiabetic and Antioxidant potential of Andrographis paniculata Nees. leaf ethanol extract in streptozotocin induced diabetic rats. Journal of Applied Pharmaceutical Science 5: 69-76
PhD students: 01 (completed), 03 (ongoing)
PG Students: 10 (completed), 02 (ongoing)
UG students: 03 (completed), 02 (ongoing)
Undergraduate-
Basic Microbiology, Medical Microbiology
Postgraduate-
General Microbiology, Medical Microbiology, Agricultural Microbiology
Research projects
Extramural Funding
Extramural Funding
- Attenuation of Pseudomonas aeruginosa virulence by dietary phytochemicals from vegetables as quorum sensing inhibitors, Principal Investigator, funded by DBT, 2013-2017.
- Biofilm formation and virulence gene expression in environmental and clinical isolates of Pseudomonas aeruginosa, Principal Investigator, funded by Nitte DU, 2016-2018
- Effect of carbohydrate on quorum sensing mediated pathogenicity in Pseudomonas aeruginosa, Principal Investigator, funded by Nitte DU
- Use of phytochemicals in inhibiting quorum sensing mediated biofilm formation in Acinetobacter baumanii, Principal Investigator, funded by Nitte DU
- Biocontrol of biofilm forming bacteria isolated from diabetic ulcers using phages, Co-principal Investigator, funded by Nitte DU
Dr. AKHILA D.S
- Designation Assistant Professor
- Email akhila@nitte.edu.in
- Contact No. .
- Joining date 09-06-2016
My research emphasizes on virulence in foodborne/zoonotic pathogens and the use of antisense technologies to combat drug resistance in bacteria. My current research focuses on developing diagnostic/ immunotherapeutic assays for animal viruses and isolation of bioactive compounds from marine sources.
- Master of Science (Microbiology), Karnataka Veterinary, Animal and Fisheries Sciences University, 2010
- Doctor of Philosophy (Microbiology), Karnataka Veterinary, Animal and Fisheries Sciences University, 2015
- Assistant Professor, Nitte University Centre for science education and research, Mangaluru (2016 – till date)
- Research Scholar, College of Fisheries, Mangaluru (2015 –2016)
- Assistant Professor, SDM PG College, Ujire (2014 - 2015)
- Senior Research Fellow, Veterinary College, Bengaluru (2010-2011)
Recombinant protein, RNAi Technology, Phage therapy, Bioactive compounds
- Recipient of Best Poster Presentation award in 7th International Multidisciplinary E-Conference on 2021
- CSIR-Summer Research Training Programme (ONLINE) at CSIR-Central Food Technological Research Institute, Mysuru, held during June - August, 2020
External member, Board of Studies in Department of Biotechnology, SDM Ujire
- Life Member, Association of Microbiologist of India
- Life Member, The Society of Biological Chemist
- Life Member, Professional Fisheries Graduate Forum
- Life Member, College of Fisheries Alumni Association Forum
- Member, The Society of Biological Chemist
- Member, Professional Fisheries Graduate Forum
- Ashwath P, Deekshit VK, Rohit A, Rai P, Aditya V, Babu N, Karunasagar I, Dharnappa Sannejal A. Sequence-Specific Gene Silencing of acrA in the Multi-drug Efflux System AcrAB Induces Sensitivity in Drug-Resistant Klebsiella pneumoniae. Molecular Biotechnology. 2022 Nov 15:1-8.
- Ashwath P, Somanath D, Sannejal AD. CRISPR and Antisense RNA Technology: Exploiting Nature's Tool to Restrain Virulence in Tenacious Pathogens. Molecular Biotechnology. 2022 Aug 18:1-1.
- Anshida M, Juliet RM, Mamatha BS, Akhila DS, Vittal R. Incidence of Aflatoxin in Ready to Eat Nuts from Local Food Markets in Mangaluru, India. Journal of Health and Allied Sciences NU. 2022 Jul 1.
- Poojari K, Akhila DS, Raj JM, Santhosh KS, Kenjar A, Ashwath P. Biocontrol of Escherichia coli and Salmonella in poultry meat using phage cocktail. Iranian Journal of Veterinary Research. 2022;23(3):270-274. doi: 10.22099/IJVR.2022.41490.6030
- A.S. Srujana, J. Sonalika, D.S. Akhila, M.R. Juliet, P. Sheela. 2021 Isolation of Phages and Study of their In vitro Efficacy on Staphylococcus aureus Isolates Originating from Bovine Subclinical Mastitis. Indian Journal of Animal Science. 2022 June; 56(6):754-758. doi: 10.18805/IJAR.B-4331
PhD student 03 (ongoing), PG students 07 (completed), 03 (ongoing), Ug students 04
Undergraduate-
General biochemistry, Food and Water Borne Pathogens, Diagnostic lab techniques
Postgraduate-
Biochemistry, Food chemistry, Industrial and Food Microbiology, Marine Microbiology, Food standards certifications and quality control, Techniques in food science
General biochemistry, Food and Water Borne Pathogens, Diagnostic lab techniques
Postgraduate-
Biochemistry, Food chemistry, Industrial and Food Microbiology, Marine Microbiology, Food standards certifications and quality control, Techniques in food science
Intramural Funding
- Novel RNAi therapeutic approach to combat multidrug resistance in Klebsiella species, Principal Investigator, funded by NitteDU, 2018-2020
- Development of siRNA conjugated nanoparticle against multidrug resistant Klebsiella pneumoniae for effective gene silencing, Principal Investigator, funded by NitteDU, 20 Principal Investigator, 20-2022
• Metagenomic Approaches to Identify Fish Gut Microbiome and the Effect of Prebiotic Supplements on Gut Microbes and Health Management chapter is published in the book entitled as Biotechnological Advances in Aquaculture Health Management, (2021), Springer.
• Klebsiella pneumoniae infections and antimicrobial drug resistance chapter is published in the book entitled as Model organism for microbial pathogenesis, biofilm formation and antimicrobial discovery (2020), Springer, ISBN 978-981-15-1694-8.
'Klebsiella pneumoniae infections and antimicrobial drug resistance' chapter is published in the book entitled as Model organism for microbial pathogenesis, biofilm formation and antimicrobial discovery (2020), ISBN 978-981-15-1694-8.
Dr. MAMATHA BS
- Designation Assistant Professor G-II
- Email mamatha.bs@nitte.edu.in
- Contact No. .
- Joining date 03-05-2017
Dr. Mamatha BS completed her Ph.D. from CFTRI, Mysore. Pursued teaching as my career and joined St. Aloysius College (Autonomous), Mangalore from 2014- 2017. Later, she joined NUCSER in 2017. She has 18 research articles and external reseach projects to her credits. Her research interest lies in two areas of food science, the bioavailability of lutein (xanthophyll carotenoid) in mice model and antihypertensive peptides from fish protein hydrolysates.
Doctor of Philosophy (Nutritional Biochemistry), Central Food Technological Research Center (CFTRI), University of Mysore, Mysore, 2013
Master of science (Food Science and Nutrition), University of Mysore, 2002
Assistant professor, Nitte University Centre for Science Education and Research, Mangaluru (2016- till date).
Assistant Professor, St. Aloysius College, Mangaluru (2014-2017).
Sr. Research Scientist, Supreem Pharmaceutical Pvt. Ltd., Nanjangud (2012-2013).
ICMR Research Fellow, Dept. of Biochemistry and Nutrition (2007-2012)
Project Assistant, Department of Sensory Science, Central Food Technological Research Institute, Mysore (2004-2007).
Food Safety
Nutritional Biochemistry
Food Technology
- Nutrition Society of India (NSI) prize for the Best Oral Presentation during, 2019
- Certificate of appreciation awarded in recognition of achievement/ dedicated and valuable service towards enhancing quality of education in "Sambhrama" 2015 and 2017, St. Aloysius college, Mangalore
- Senior Research fellowship by the Indian Council of Medical Research (ICMR), 2007.
- Awarded First prize for the poster presented, ICFOST-2005, NIMHANS, Bangalore.
- Best Researcher Award 2022 for Nitte University Centre for Science Education and Research (NUCSER) 2022.
- Best Researcher Award 2022 for Nitte (DU).
- Member, Hostel committee, NUCSER
- Member, Academic committee, NUCSER
- In-charge, Women cell, NUCSER
- Member, Student welfare committee, NUCSER
- Member, Women cell, NUCSER
- Member, Library committee, NUCSER
Member, Association of Food Technology Research Institute (AFSTI)
Member, Nutrition Society of India (NSI)
- Mamatha, B.S., Ranganathan, A., Bhatiwada, N., Talahalli, R.R., Vallikannan, B. (2015) Dietary components affect the plasma and tissue levels of lutein in aged rats with lutein deficiency a repeated gavage and dietary study. Journal of Food Science 80(10):H2322- 30.
- Yathisha UG, Ishani Bhat, Iddya Karunasagar & Mamatha BS, Antihypertensive Activity of Fish Protein Hydrolysates and its Peptides, Critical Reviews in Food Science, 2019, 59(15 ), 2363-2374.
- Ishani Bhat, Yathisha UG, Iddya Karunasagar and Mamatha BS, Nutraceutical approach to enhance lutein bioavailability via nano-delivery systems, Nutrition reviews, 2020, 78(9):709-724.
- Bhat I and Mamatha BS. Genetic factors involved in modulating the bioavailability of lutein. Nutrition Research. 2021:91:36-43.
- Ishani bhat, Nishithkumar Jogi, Mamatha BS, Carotenoid composition of locally found seaweeds of Dakshina Kannada district in India, Algal research, Volume 53, March 2021, 102154.
- Nishithkumar Jogi, Undiganalu Gangadharappa Yathisha, Ishani Bhat an Mamatha Bangera Sheshappa, Antihypertensive activity of orally consumed ACE-I inhibitory peptides, Critical Reviews in Food Science and Nutrition, 62(32), 2022, 8986-8999. https://doi.org/10.1080/10408398.2021.1938508.
- Yathisha, U. G., Karunasagar, I, and Mamatha BS. Bioactivity and Functional Properties of Protein Hydrolysate from Muscle and Visceral Waste of Ribbon Fish (Lepturacanthus savala) Extracted by three Different Proteolytic Enzymes. Journal of Biologically Active Products from Nature, 2021, 11(4), 363-379.
- Ishani Bhat, Baskaran V, Mamatha BS, Influence of fatty acids in edible oils on lutein micellization and permeation in a simulated digestion model, Food Bioscience. 2021, DOI: 10.1016/j.fbio.2021.101423.
- Yathisha UG, Mahendra Gowdru Srinivasa, Revanna Siddappa BC, Subankar P Mandal, Sheshagiri R Dixit, Pujar GV and Mamatha BS, Isolation and characterization of ACE-I inhibitory peptides from ribbonfish for a potential inhibitor of the main protease of SARS-CoV-2: An in-silico analysis. 2021, Accepted for publication in Proteins: Structure, Function, and Bioinformatics. 2022; 90: 982-992.
- Yathisha UG, Sneha Vaidya and Mamatha Bangera Sheshappa. Functional Properties of Protein Hydrolysate from Ribbon Fish (Lepturacanthus Savala) as Prepared by Enzymatic hydrolysis (2022). Accepted in International Journal of Food properties. 2022, 25(1), 187-203.
- Ishani Bhat, Nimmi Mol Jose, Mamatha BS, Oxidative stability of lutein on exposure to varied extrinsic factor (accepted for publication in Journal of Food Science and Technology).
- D'Souza, LC, Dwivedi S Raihan F, Yathisha UG, Raghu SV, Mamatha B. S & Sharma, A. (2022). Hsp70 overexpression in Drosophila hemocytes attenuates benzene‐induced immune and developmental toxicity via regulating ROS/JNK signaling pathway. Environmental Toxicology, 37(7):1723-1739.
- Vinitha D'Souza, Meghashree, Murali Badanthadka, K. Vijayanarayana, B S Mamatha, K Vijayanarayana, Effect of nutritional status on acetaminophen pharmacokinetic profile, Toxicology and Applied Pharmacology. 438,2022, 115888.
- Ishani Bhat, R.J. Madhura, Murali Badanthadka, Bangera Sheshappa Mamatha. Cow ghee as an efficient carrier to improve oral bioavailability of lutein, Food Chemistry 389 (2022) 133046.
- Yathisha UG, Tanaaz Moideen, Ishani bhat, Feby Luckose and Mamatha BS, Physicochemical properties and angiotensin-I converting enzyme inhibitory activity of lipid-free ribbon fish (Lepturacanthus savala) protein hydrolysate. Journal of Food Science and Technology.
PhD students: 02 (completed) 03 (ongoing) PG Students: 18 (completed) UG Students: 04 (completed)
Undergraduate-
Food Spoilage and Preservation
Postgraduate-
Food Packaging and Storage, Food Standards Certification and Quality Control, Food Standards, laws and regulation, Marine Food Technology
As PI:
- Preparation of fish protein hydrolysate having bioactive properties and its use in food funded by DST-SERB, 2016-2019 [Budget: 22,31,000]
- Nano-formulation of lutein to improve bioavailability in the prevention of Age-Related Macular Degeneration, funded by ICMR, 2019-2022 [Budget: 24.27 lakhs]
- An approach to determine in vitro bioaccessibility of lutein, funded by Nitte (DU), 2018-2020 [Budget: 1.75 lakhs]
- Stability and absorption of fucoxanthin, funded by Nitte (DU), 2020-2022 [Budget: 1.75 lakhs]
- Designing lutein nano-formulation: a therapeutic approach towards Parkinson's Disease, funded by ICMR, 2022 [Budget: 31,30,000 lakhs]- approved
- NU-TEC farmers training Centre for development of value-added agriculture products, funded by DST-TEC, 2019-2024 [Budget: 500 lakhs].
Dr. SUDARSHAN KINI
- Designation Scientist (G-II)
- Email Sudarshan.kini@nitte.edu.in
- Contact No. .
- Joining date 20-08-2018
Dr. Sudarshan Kini is a Bionanotechnologist who obtained Ph.D. (Nanotechnology) from the Indian Institute of Technology Bombay and has Post-Doctoral experience from Manipal University. His research areas are the fabrication of biomaterial scaffolds for the 3D culturing of cancer cells and Pseudomonas biofilms. He is also working on developing quantum dot-based fluorescent nanobiosensors to detect MRSA (Methicillin-resistant Staphylococcus aureus).
- Doctor of Philosophy (Nanobiomaterials), Indian Institute of Technology Bombay, 2015
- Master of Science (Biochemistry), Bharathiar University, 2008
Scientist II, Nitte University Centre for Science Education & Research (2018 - Present)
Postdoctoral Research Fellow (Nanodiagnostics), Manipal Academy of Higher Education (2015 - 2018)
Research Associate, Indian Institute of Technology Bombay (Jan 2015 to June 2015)
- Development of Nanobiomaterials and nanodiagnostics for biomedical applications
- Establishment of three-dimensional cell culture to generate biomimetic cancer models.
- Nanobiomaterials and Nanodiagnostics
- Biomimicking Scaffolds
- Cancer Cell Biology
Best Paper award at International conference on Recent Advances in Materials Science and Biophysics at Mangalore, 2018.
Best poster in the International symposium on Nanotechnology and Cancer Theranostics (ISNACT-2015) at IIT Bombay, 2015
GATE qualified with 98.27 percentiles, All India rank 226, score 476.
- In-charge, Institutional Student Innovation Club, NUCSER
- Coordinator, Electoral Literacy Club, NUCSER
- Member, Institutional Ethics Committee, NUCSER
- Member, Academic committee, NUCSER
- Member secretary, Institutional committee against substance abuse, NUCSER
- Member, Youth Red Cross committee, NUCSER
- Member, Institutional Placement & Career Guidance Cell, NUCSER
- Alumni coordinator for NUCSER
- Member, Lab resource committee, NUCSER
- Hostel committee, NUCSER
- Coordinator, Electoral Literacy Club, NUCSER
- Member, Youth Red Cross committee, Nitte DU
Journal publications:
Filed: Biodegradable three dimentional scaffolds to grow cells in serum deprived condition, Patent application no. 202141033609. Google Scholar: https://scholar.google.com/citations?user=ixAqu2MAAAAJ&hl=en
ResearchGATE: https://www.researchgate.net/profile/Sudarshan_Kini
Orcid Id: 0000-0001-5253-9938
Scopus Id: 53866809000
Researcher Id: R-6434-2019
- Paithankar JG, Kushalan S, Hegde S, Kini S* and Sharma A*. Systematic toxicity assessment of CdTe quantum dots in Drosophila melanogaster. Chemosphere 2022;295:133836. https://doi.org/10.1016/j.chemosphere.2022.133836. (IF .7)
- Badekila, AK., Rai P, and Kini, S*. Identification and evaluation of an appropriate housekeeping gene for real time gene profiling of hepatocellular carcinoma cells cultured in three dimensional scaffold. Mol Biol Rep 49, 797-804 (2022). https://doi.org/10.1007/s11033-021-06830-y (IF 2.36)
- Badekila AK, Kini S*, Jaiswal AK, Fabrication techniques of biomimetic scaffolds in three‐dimensional cell culture: A review, J Cell Physiol. 2020:236:741-762. https://doi.org/10.1002/jcp.29935. (Q2, IF 6.5)
- Kini S, Kulkarni SD, Ganiga V, Nagarakshit TK, Chidangil S. Dual functionalized, stable and water dispersible CdTe quantum dots: Facile, one-pot aqueous synthesis, optical tuning and energy transfer applications. Mater Res Bull 2019;110:57-66. doi:10.1016/j.materresbull.2018.10.013. (Q2, IF.4.6)
- Kini S, Ganiga V, Kulkarni SD, Chidangil S, George SD. Sensitive detection of mercury using the fluorescence resonance energy transfer between CdTe/CdS quantum dots and Rhodamine 6G. J Nanoparticle Res 2018;232. doi:10.1007/s11051-018-4320-5. (Q3, IF.2.25)
- Kini S, Bahadur D, Panda D. Mechanism of anti-cancer activity of benomyl loaded nanoparticles in multidrug resistant cancer cells. J Biomed Nanotechnol 2015;11:877-889. doi:10.1166/jbn.2015.1998. (Q2, IF.4.1)
Filed: Biodegradable three dimentional scaffolds to grow cells in serum deprived condition, Patent application no. 202141033609. Google Scholar: https://scholar.google.com/citations?user=ixAqu2MAAAAJ&hl=en
ResearchGATE: https://www.researchgate.net/profile/Sudarshan_Kini
Orcid Id: 0000-0001-5253-9938
Scopus Id: 53866809000
Researcher Id: R-6434-2019
Ph.D scholars: 4 Postgraduate students: 08 Undergraduate students: 09
Undergraduate
General Biochemistry, Radiation Biology, Cancer Biology
Postgraduate
Biochemistry, Medical Biochemistry, Nanobiotechnology, Biology and Genetics of Cancer
General Biochemistry, Radiation Biology, Cancer Biology
Postgraduate
Biochemistry, Medical Biochemistry, Nanobiotechnology, Biology and Genetics of Cancer
Principal Investigator
- A novel rapid sensitive fluorescent resonance energy transfer technique for selective detection and quantification of methicillin resistant Staphylococcus aureus, funded by DST-SERB-Early Career Research, 2019-2021 [Budget: Rs. 36,13,764/-]
- Development and characterization of a novel three-dimensional biofilm of Pseudomonas aeruginosa for the assessment of the mechanism of nonmucoid to mucoid strain conversion, virulence, antibiotic resistance and macrophage immune response, funded by ICMR-Adhoc, 2022-2024 [Budget: Rs. 32,53,395]
- Nano-formulation of lutein to improve bioavailability in prevention of Age-Related Macular Degeneration, funded by ICMR, 2019-2021 [Budget: Rs. 24,27,752/-]
- Investigating the antimicrobial efficacy of NANOBIOTICS against multidrug resistant gut pathogens, funded by DHR-ICMR, 2021-2023 [Budget: Rs. 47,40,247]
- Development of immunofluorescent nanodiagnostic assay as a point-of-care detection of dengue virus, funded by DSt/TDT, 2021-2022 [Budget: Rs. 22,60,224]
- Elucidation of platelet activation and NLRP3 inflammasome response in platelets during invasive Vibrio vulnificus infection to understand its potential role in the immunopathogenesis, funded by ICMR, 2022-2024 [Budget: Rs. 22,62,395]
Dr. JULIET ROSHINI MOHAN RAJ
- Designation Assistant Professor - (G-I)
- Email julietm@nitte.edu.in
- Contact No. .
- Joining date 01-09-2014
In the current scenario where antibiotics no longer work, the need for alternative strategies have looked at phage therapy and I have been actively involved in research on phage-based therapeutics not only for human therapeutic use but also biocontrol in foods for more than 10 years.
- Addressal officer, Institutional Grievance, NUCSER
- Member, Student Welfare Committee, NUCSER
- Member, Lab infrastructure committee, NUCSER
- Member, Women’s Cell, NUCSER
- Member, Institutional Research Cell, NUCSER
- Doctor of Philosophy ( Biological Sciences), Nitte (Deemed to be University) , 2018
- Master of Science( Microbiology), Bangalore University,2007
Assistant Professor - Grade I, Nitte University Centre for science education and research, Mangaluru (Nov 2018 till date)
Lecturer, Nitte University Centre for science education and research, Mangaluru (Sep 2014 –Oct 2018 )
Project Assistant, UNESCO MIRCEN for Marine Biotechnology, College of Fisheries, Mangaluru (Feb 2013-July 2014).
Senior Research Associate, Gangagen Biotechnologies Pvt. Ltd.,Bengaluru (July 2017-Feb 2010).
Phage therapy and phage biology
Infectious diseases
Bacteriology
Summer Fellowship awarded jointly by Indian Academy of Science-Indian National Science Academy and National Academy of Science India, 2019
Japan-Asia Youth Exchange program in Science (SAKURA exchange), 2017
CSIR-UGC NET for Lectureship, 2013
- Addressal officer, Institutional Grievance, NUCSER
- Member, Student Welfare Committee, NUCSER
- Member, Lab infrastructure committee, NUCSER
- Member, Women's Cell, NUCSER
- Member, Institutional Research Cell, NUCSER
- Institutional Grievance Redressal officer, NUCSER
- Member, Lab infrastructure committee, NUCSER
- Member, Women's Cell, NUCSER
- Member, Indian Network for Soil Contamination Research, India
- Member, Society for Bacteriophage Research and Therapy, India
- Prabhakara AM, Nanjappa DP, Kotian A, Kalladka K, Chakraborty G, Vittal R, Raj JR, Deekshit VK, Chakraborty A (2022) Wild-type and cancer-prone zebrafish exhibit distinct gut microbial diversity and differential anti-inflammatory response upon infection. Journal of Biosciences. Dec;47(4): Article 65.
- Poojari K, Akhila DS, Raj JM, Santhosh KS, Kenjar A, Ashwath P (2022) Biocontrol of Escherichia coli and Salmonella in poultry meat using phage cocktail. Iranian Journal of Veterinary Research.2022;23(3):270-274.
- Rai P, Shetty SS, Prabell S, Kuntar A, Pinto D, Kumar BK, Divyashree M, Raj JRM, Premanath R, Deekshit VK, Karunasagar I, Karunasagar I(2022) Characterisation of broad-spectrum phiKZ like jumbo phage and its utilisation in controlling multidrug-resistant Pseudomonas aeruginosa isolates. Microbial Pathogogenesis.172:105767. doi: 10.1016/j.micpath.2022.105767.
- Srujana AS, Sonalika J, Akhila DS, Juliet MR, Sheela P(2022) Isolation of phages and study of their In vitro efficacy on Staphylococcus aureus isolates originating from bovine subclinical mastitis.Indian Journal of Animal Research.56:754-758.
- Vittal R, Mohanraj JR, Chakraborty G (2022) Rapid Detection of Salmonella spp from Meat: Loop Mediated Isothermal Amplification (LAMP), Journal of Pure Applied Microbiology.16(2):929-936 .
- Vittal R, Raj JR, Kumar BK, Karunasagar I (2022) Advances in environmental detection and clinical diagnostic tests for Legionella species. Journal of Health and Allied Sciences NU, India. 2022 ;12(02): 168-174.
- Hassan M, Vittal R, Raj JM, Chakraborty G (2022) Loop-mediated isothermal amplification (LAMP): a sensitive molecular tool for detection of Staphylococcus aureus in meat and dairy product. Brazilian Journal of Microbiology. 2022;53(1):341-347.
PhD (4 ongoing)
M.Sc (8 completed, 2 ongoing)
B.Sc (10 completed)
Undergraduate-
Physical and Inorganic Chemistry
Post graduate-
Microbial Physiology
Food Microbiology
Medical Microbiology
Research Methodology
Techniques in Biomedical Science
Bioprocess Engineering and Technology,
Bioprocessing and Fermentation Technology
Marine Bioprocess Technology
Bioethics and Biosafety
Food Microbiology
Medical Microbiology
Research Methodology
Techniques in Biomedical Science
Bioprocess Engineering and Technology,
Bioprocessing and Fermentation Technology
Marine Bioprocess Technology
Bioethics and Biosafety
Bacteriophages and their products for controlling the biofilms of drug resistant Klebsiella pneumoniae, Co-Investigator, SERB,2022-2024
Intramural Funding
Intramural Funding
- Biocontrol of biofilm forming bacteria isolated from diabetic ulcers using phage, funded by NitteDU,as PI, 2018-2020
- Utility of polymerase chain reaction in the identification of dermatophytes in recalcitrant dermatophytosis, funded by NitteDU, Co PI , 2018-2020
- Evaluation of resistant genes in recalcitrant Dermatophytosis - A PCR based study, funded by NitteDU, 2018-2020
- Identification of novel enzybiotics using phage fragmentation, Principal Investigator, funded by NitteDU, 2020-2022
Mrs. RAJESHWARI B VITTAL
- Designation Assistant Professor G-I
- Email rajeshwari.vittal@nitte.edu.in
- Contact No. .
- Joining date 14-08-2014
I am presently working as Assistant Professor in NUCSER, and have 8 years of teaching experience. As a researcher, I have been working in environmental toxicology- related areas for the past 15years. During my PhD 2015-2022, I have worked extensively on the identification of Legionella pneumophila, a pathogen of respiratory pneumonia. In addition, my expertise is in analysis of water quality parameters, microbiological techniques (soil and water), molecular techniques. I have been guiding the PG students as a guide and a Co-guide. I am also involved in analyzing external samples of food and water, and providing training to personnel from different parts of the country. I have a few GenBank submissions in my name. At present, my focus is on understanding the effects of several environmental toxicants including microplastics using the zebrafish model system. I intend to find out the changes in environmental parameters and phenotypic changes of living organisms in the polluted area.
• Doctor of Philosophy ( Biological Sciences), Nitte
(Deemed to be University) , 2022
- Senior Lecturer, Nitte University Centre for science education and research, Mangaluru, (2018-till date)
- Lecturer, Nitte University Centre for science education and research, Mangaluru (2014 – 2018 )
- Senior Research Fellow, Department of Microbiology, KVAFSU (2014 to 2014)
- Senior Research Fellow, Department of Ecology & Environment, KVAFSU, (2008 to 2010)
Microbiology
Infectious Disease
Environment &toxicology
- Japan- Asia Youth Exchange Program in Science (SAKURA exchange), awardee 2017
- Training workshop on Antimicrobial Susceptibility Testing at PGIMER, Chandigarh, 2016
- Participant, Responsible Conduct of Science Research sponsored by US National Academy of Science, 2015
- Member, Student welfare committee, NUCSER
- Institutional Alumni (Coordinator)
- Institutional committee against substance abuse(member)
- Institutional women cell (member)
- Student grievance cell (member)
Member of The Society of Biological Chemists (SBC), India
- Aprathi MP, Dechamma PN, Kotian A, Krithika K, Chakraborty C, Vittal R, Raj JRM ,Deekshit VK, Chakraborty A. Wild type and cancer-prone zebrafish exhibit distinct gut microbial diversity and show differential anti-inflammatory response upon infection. Journal of Biosciences, 2022
- Hassan M, Vittal R, Raj JM, Chakraborty G. Loop-mediated isothermal amplification (LAMP): a sensitive molecular tool for detection of Staphylococcus aureus in meat and dairy product. Braz J Microbiol. 2022 Jan 29. doi: 10.1007/s42770-021-00659-0
- Vittal R, Mohan Raj M, Chakraborty G. "Rapid detection of Salmonella spp from meat: Loop mediated isothermal amplification (LAMP)". J Pure Appl Microbiol. 2022;16(2): 929-936. Doi: https://doi.org/10.22207/JPAM.16.2.13.
- Anshida M , MohanRaj JR1, Mamatha B.S, Akhila D.S, and Vittal R. Incidence of Aflatoxin in ready to eat nuts from local food markets in Mangaluru, India. Journal of Health and Allied Sciences NU. 2022
- Vittal R, Kumar BK, Karunasagar I, Mohan Raj JR. Genetic Diversity of the Legionella pneumophila dotA Gene detected on surfaces of respiratory therapy equipment. JPure Appl Microbiol. 2021;15(2):695-700. doi: 10.22207/JPAM.15.2.20
- Vittal R, Mohan Raj JR, Kumar, B.K. and Karunasagar, I. Advances in Environmental Detection and Clinical Diagnostic Tests for Legionella Species. Journal of Health and Allied Sciences NU. 2021 DOI https://doi.org/10.1055/s-0041-1731863
- Vittal R, Mohan Raj JR, Kumar BK, Karunasagar I Iron Content as an Indicator for Legionella Species in Artificial Water Systems.Medico Legal Updates.2021;21:803-8.
- Anoopkrishna Rai, Vittal R. Juliet R. Mohan Raj.Isolation, Characterization, and Comparison of Efficiencies of Bacteriophages to Reduce Planktonic and Biofilm-Associated Staphylococcus aureus. Journal of Health and Allied Sciences NU.2020 DOI https://doi.org/ 10.1055/s-0040-1715773
- Mohan Raj JR, Vittal R, Shivakumaraswamy SK, Deekshit VK, Karunasagar I. (2017) Comparison of antimicrobial resistance in Gram negative bacteria isolated from effluents in coastal districts of Karnataka, India. NUJHS Dec; 7(4): 16-20
- Deviprasad R, Subramanyam G, Vittal R, Nayak B.B, Karunasagar I. Ammonia oxidising microbes and physicochemical parameters of effluent treatment plants of fish processing industries. Frontier journal of veterinary and Animal Sciences.
PG Students: 04 (completed), 02 (ongoing)
UG Students: 03 (completed)
Undergraduate-
Cell and Developmental Biology, General lab Practice
Postgraduate-
Food microbiology, Research Ethics & IPR, Food Processing and Preservation, Techniques in Biomedical Science, Food additives & adulterants, Techniques in Food Science
Research projects
Intramural Funding
Intramural Funding
- Biocontrol of biofilm forming bacteria isolated from diabetic ulcers using phage, funded by NitteDU, 2018-2020 [Budget 1.7 lakhs]
- Detection of micro and nanoplastics in bottled water and devaluation of the associated health effects using the zebrafish model system" Principal Investigator, funded by Nitte DU, 2020.
DR AKSHATHA KOTIAN
- Designation Assistant Professor G-I
- Email akshatha.kotian@nitte.edu.in
- Contact No. .
- Joining date 01-06-2024
My academic journey, with the blend of chemistry/biotechnology and biomedical sciences has equipped me with a comprehensive understanding of application of science into human health and diseases. I am interested in exploring and integrating my knowledge on antimicrobial resistance, biofilm, molecular and microbiology into the domain of food science and technology to address complex challenges of food safety and public health. I am also keen on research involving functional foods and prebiotics for a sustainable development strategy and promote environmental stewardship.
- Doctor of Philosophy (Biological science), NUCSER, Nitte (DU) - 2023
- Master of Science, Biomedical science, NUCSER, Nitte (DU) - 2017
- Bachelor of Science (Biotechnology/Chemistry/Zoology), St. Aloysius college, Mangalore - 2015
- • Senior Project Associate, DST Technology Enabling Centre, Nitte (DU) – Aug 2022- May 2024
- Junior Project Associate, DST Technology Enabling Centre, Nitte (DU) – Aug 2020-July 2022
- PhD Scholar , NUCSER, Nitte (DU) Fellowship Aug 2017 – July 2020rn
- Microbiology
- Molecular biology
- Infectious Diseases
- Biotechnology
- Food Science and Technology
- Best poster presentation award at the 62nd Annual International Conference of Association of Microbiologists of India (AMI)-2022
- DST AWSAR 2021, GoI, Award for Best Popular Science Stories entitled "Resistance is Bacterial Super power, What's yours? - A TED talk by the Superbug"rn
- Karnataka State Eligibility Test (K-SET/2019-20) for assistant for assistant professor in life sciences
- Recipient of Japan-Asia Youth Exchange Program in Science funded by JST and organized by University of Miyazaki - 2016
- Presented work at Indian Biofilm society - Bile and Biofilm Association - 2017
- Presentation in SAKURA science plan student seminar 2016 (Japan) - Bio-Med-Tech-and engineering: An update.rn
- Academic excellence in Masters for scoring the second highest aggregate, 2017.
- Member, Institutional Gender Sensitization Cell, NUCSER
- Kotian A, Aditya V, Sheikh J, Saikrishnan S, Rai P, Chakraborty A, Karunasagar I, rnDeekshit VK. Effect of NaCl, high iron, iron chelator and antibiotics on growth, rnvirulence gene expression and drug susceptibility in non-typhoidal Salmonella: an in rnvitro fitness study. Archives of Microbiology. 2022 Nov;204(11):1-9.
- Kotian A, Aditya V, Jazeela K, Karunasagar I, Karunasagar I, Deekshit VK. Effect of rnbile on growth and biofilm formation of non-typhoidal Salmonella serovars isolated rnfrom seafood and poultry. Research in Microbiology. 2020 Jul 1;171(5-6):165-73.
- Kotian A, Aditya V, Jazeela K, Karunasagar I, Karunasagar I, Deekshit VK. Effect of rnbile on biofilm forming ability and fitness of multidrug resistant non-typhodial rnSalmonella serovars. International Journal of Infectious Diseases, 2020, Volume 101, rn76: 0183
- Aditya V, Kotian A, Sanil A, Thaseena PM, Karunasagar I, Deekshit VK. Survival and rnVirulence Potential of Drug-Resistant E. coli in Simulated Gut Conditions and Antibiotic Challenge. International Journal of Environmental Research and Public rnHealth. 2022 Oct 6;19(19):12805
- Aditya V, Kotian A, Saikrishnan S, Rohit A, Mithoor D, Karunasagar I, Deekshit VK. rnEffect of ciprofloxacin and in vitro gut conditions on biofilm of Escherichia coli rnisolated from clinical and environmental sources. Journal of Applied Microbiology. rn2022, 132 964-977..
- Prabhakara AM, Nanjappa DP, Kotian A, Kalladka K, Chakraborty G, Vittal R, Raj rnJR, Deekshit VK, Chakraborty A. Wild-type and cancer-prone zebrafish exhibit distinct rngut microbial diversity and differential anti-inflammatory response upon infection. rnJournal of Biosciences. 2022 Dec;47(4):1-0. rn
- Rai P, Kille S, Kotian A, Kumar BK, Deekshit VK, Ramakrishna MS, Karunasagar I, rnKarunasagar I. Molecular investigation of the dengue outbreak in Karnataka, South rnIndia, reveals co-circulation of all four dengue virus serotypes. Infection, Genetics and rnEvolution. 2021 Aug 1;92:104880.
Undergraduate
rn
rn
rnPhD students: Nil
rnPG Students: 4 (On going)
rnUG Students: 2 (On going)
rn
- rn
- Cell Biology and Methods in cell and microbiology
- Crn
- Model systems in Biomedical Research rn
rn
- rn
- Plant and animal food technology rn
rnPhD students: Nil
rnPG Students: 4 (On going)
rnUG Students: 2 (On going)
All Publications:
rnGoogle scholar: https://scholar.google.com/citations?user=TADa5z8AAAAJ&hl=en
rnGoogle scholar: https://scholar.google.com/citations?user=TADa5z8AAAAJ&hl=en
Dr. DIVYASHREE M
- Designation Scientist (G-I)
- Email divyashree.m@nitte.edu.in
- Contact No. .
- Joining date 11-10-2019
After competing my Ph.D., I have worked as Research associate and joined NUCSER as Scientist (G-I) in 2019. My research interest includes Infectious Disease Biology (Bacteriology), Antimicrobial Resistance, Food Microbiology and Biopolymers.
- Doctor of Philosophy - Allied Health Sciences (2017) – K S Hegde Medical Academy, NITTE University, Deralakatte
- MSc Microbiology (2009) - Manasagangotri, University of Mysore, Mysore
- Scientist G-I, Center for Science Education and Research, NITTE University, Mangalore (October 2019-till date)
- Research Associate, Center for Science Education and Research, NITTE University, Mangalore (April 2017-October 2019)
- Executive – Quality Control, Agila Specialities Private limited (Sterile Product Division) Bangalore (2010-2011)
- Infectious Disease Biology (Bacteriology)
- Antimicrobial Resistance in hospital and hospital wastewater
- Food Microbiology: gut microbiome, probiotics
- Biopolymer production: Polyhydroxyalkanoates a microbial plastic
- Predatory Bacterium - Bdellovibrio spp.
- SportCo-ordinator, NUCSER
- Member, Student welfare committee, NUCSER
- Member, I-CASA, NUCSER
- Divyashree M, Shama Prakash K, Veena Shetty A, Karunasagar I. Antibiotic Resistance in Extended-Spectrum Beta-Lactamase-Producing Escherichia coli Isolated from Effluents of Tertiary Care Hospitals (2015). Int J of Health Sci Res, 27-33.
- Veena Shetty, Divyashree M, Deekshit V.K, Avinash Shetty, Indrani Karunasagar. A poster on "Emergence of New Delhi Metallo-β - Lactamase (NDM - 1) - Encoding Gene among Gram Negative Bacteria Isolated from Hospital Effluents" has been published in International conference proceedings ID Week 2015 San Diego, CA.(IF: 3.2)
- M. Divyashree, Malathi Shekar, K. Shama Prakash, M. N. Venugopal, I. Karunasagar and A. Veena Shetty. Characterization of Extended Spectrum -Lactamase Producing and Non- Producing Escherichia coli Isolated from Hospital and Fish Processing Plant Untreated Wastewaters (2015). Int J Curr Microbiol App Sci, 4(10): 179-189.
- Divyashree M, Deekshit V K, Krishna Kumar Ballamoole, Veena Shetty A, Anirban Chakraborty, Indrani Karunasagar. Occurrence of antibiotic resistance among Gram negative bacteria isolated from effluents of fish processing plants in and around Mangalore (2019). Int J of Environmental Health Research.
- Divyashree M, Madhu K Mani, Dhanasekhar Reddy, Ranjith Kumavath, Debmalya Barh. Clinical Applications of Antimicrobial Peptides (AMPs): where do we stand now? (2019) Protein and Pept Lett. 26, 1-15.
- Divyashree M, Madhu K Mani, Shama Prakash K, Deekshit VK, Veena Shetty A, Avinash K Shetty, Anirban Chakraborty, Indrani Karunasagar. Hospital wastewater treatment reduces NDM positive bacteria being discharged into water bodies (2019). Water Environment Research. 1-7.
- Divyashree M, Madhu K Mani, Mamatha B S, Sudarshan Kini. Algae and cyanobacteria as a source of novel bioactive compounds for biomedical applications. Advances in Cyanobacterial Biology, Elsevier Publication, Chapter 12, 2020.
- Suhan Alva, Divyashree M, Janardhana Kamath, P S Prakash, Shama Prakash K.A study on bicarbonate supplementation effect on the progression of chronic kidney disease (2020) Indian Journal of Nephrology. 30 (2)
- Aditya V, Kotian A, Saikrishnan S, Rohit A, Mithoor D, Karunasagar I, Deekshit VK. Effect of ciprofloxacin and in vitro gut conditions on biofilm of Escherichia coli isolated from clinical and environmental sources. J Appl Microbiol. (2021) 132.2 (2022): 964-977.
- Divyashree, M., Madhu K. Mani, and Indrani Karunasagar. "Association of exopolysaccharide genes in biofilm developing antibiotic-resistant Pseudomona s aeruginosa from hospital wastewater." Journal of Water and Health 20.1 (2022): 176-184.
- Ishani Bhat, Saisree Iyer, Venessa Fernandes, Divyashree M, Bangera Sheshappa Mamatha. Challenges in oral Bioavailability of Lutein. What to know about carotenoids. New York: Nova Science Publisher , 2021, 27-66.
- Divyashree, M., and Madhu K. Mani. "Detection and Real-time PCR Assay for the Quantification of Carbapenemase Gene [bla. sub. NDM-1] in Hospital Effluent." Journal of Pure and Applied Microbiology 15.4 (2021): 2403-2409.
- Rai P, Shetty SS, Prabell S, Kuntar A, Pinto D, Kumar BK, Divyashree M, Raj JRM, Premanath R, Deekshit VK, Karunasagar I, Karunasagar I. "Characterisation of broad-spectrum phiKZ like jumbo phage and its utilisation in controlling multidrug-resistant Pseudomonas aeruginosa isolates." Microbial Pathogenesis 172 (2022): 105767.
UG students: 02 completed, PG students: 03 completed, 02 ongoing; PhD: 2 ongoing
Undergraduate: Basic Microbiology, Medical Microbiology, Good Laboratory Practices
Post Graduate: Food Microbiology, Environmental Microbiology, Microbial Physiology, Molecular Diagnostics
Post Graduate: Food Microbiology, Environmental Microbiology, Microbial Physiology, Molecular Diagnostics
Extramural
- Screening and production of Polyhydroxybutyrates (PHB) by bacterial strains isolated from hydrocarbon contaminated soil using metagenomic approach. Principal Investigator, Funded by UGC-Faculty research promotion scheme, Start-up-Grant, 2021-2024
- Isolation and activity evaluation of Bdellovibrio for hospital effluent isolates against biofilm forming Pseudomonas aeruginosa . Principal Investigator, funded by Nitte DU, 2021-2023.
Dr. AKSHATH U. S
- Designation Scientist Grade-II
- Email akshath.uchangi@nitte.edu.in
- Contact No. .
- Joining date 08-10-2020
Dr. Akshath completed his Ph.D. at CSIR-CFTRI, Mysore, with a specialization in Biosensors and Bio-imaging. His work was focused on nanoparticle-based biosensors to detect food contaminants and toxins using enzymes/aptamers as biorecognition elements. After his Ph.D., he was awarded the prestigious Marie Skłodowska-Curie fellowship (MCIFs) at the University of Leeds, UK. His work was focused on polyvalent glycan-nanoparticles to decipher HIV/Ebola infections using dendritic cell receptors-DCSIGN/R. His research at NUCSER is focused on developing nano-sensors to detect contaminants, bacteria, viruses etc. His research also focuses on glycan-nanoparticles to decipher bacterial/viral infections and inhibition. He has published papers in journals of international repute ex-Journal of American Chemical Society, Biosensors & Bioelectronics, etc.
- Doctor of Philosophy (Life Sciences), CSIR-Central Food Technological Research Institute, Mysore-2018 (Specialization-Nanobiotechnology)
- Master of Science (Biochemistry), University of Mysore, 2008
- Project assistant, CSIR-CFTRI-2010-2014-NPMASS-DRDO Funded project
- PhD-2014-2018, CSIR-CFTRI Mysore
- Marie-Curie Fellow, School of Chemistry, University of Leeds, UK-2018-2020
No. of PhDs
Ongoing: 2
No. of UGs guided: 4
No. of PGs guided:
Ongoing as guide:3
- Marie-Curie Individual Fellowship-17/18-University of Leeds, UK
- European Commission-Marie-Curie Fellow (Awarded MC-Individual Fellowship 17/18) School of Chemistry, University of Leeds, UK
- CSIR-CFTRI Annual award-2017 & 2018 for best paper published in Applied Sciences- Biosensors and Bioelectronics, 85 (2016): 240-246, Biosensors & Bioelectronics, 100, 15 February 2018, 201-207
- Honored by Karnataka State Govt on 59th Independence Day on the eve of Designing new methods for Paddy cultivation-2005.
- Best oral presentation award for the presentation titled "Deciphering virus-host interactions using polyvalent glyco-nanoparticles" at the 62nd Annual International Conference of AMI held at University of Mysore, Mysore
- Member, Consumable committee, NUCSER
- Member, Vigilance committee, NUCSER
- Member, Royal Society of Chemistry
Conference/Journal publications
Selected Journal publications:
- Budhadev, D., Poole, E., Nehlmeier, I., Liu, Y., Hooper, J., Kalverda, E., Akshath, U.S., Hondow, N., Turnbull, W.B., Pohlmann, S. and Guo, Y., 2020. Glycan-Gold Nanoparticles as Multifunctional Probes for Multivalent Lectin-Carbohydrate Binding: Implications for Blocking Virus Infection and Nanoparticle Assembly. J. Am. Chem. Soc. 2020, 142, 42, 18022-18034
- Wang, Weili; Kong, Yifei; Jiang, Jun; Tian, Xin; Li, Shuang; Akshath, Uchangi; Tiede, Christian; Hondow, Nicole; Yu, Anchi; Guo, Yuan; Zhou, Dejian, Nanoscale, 2020. Photon induced quantum yield regeneration of cap-exchanged CdSe/CdS quantum rod for ratiometric biosensing and cellular imaging. Nanoscale, 2020, 12, 8647-8655
- Sharma, R., Akshath, U. S., Bhatt, P., & Raghavarao, K. S. M. S. (2019). Fluorescent aptaswitch for chloramphenicol detection-Quantification enabled by immobilization of aptamer. Sensors and Actuators B: Chemical, 1 July 2019, 290, 110-117
- Akshath, U. S., and Praveena Bhatt., (2017). Supramolecular nano-sniffers for ultrasensitive detection of formaldehyde. Biosensors & Bioelectronics, 100, 15 February 2018, 201-207
- Akshath, U. S., and Praveena Bhatt. (2016) Gold nanoparticle synthesis coupled to fluorescence turn-on for sensitive detection of formaldehyde using formaldehyde dehydrogenase"- RSC Advances, 6(60), pp.54777-54784
- Akshath, U. S., and Praveena Bhatt. (2016). Tunneling of redox enzymes to design nano-probes for monitoring NAD+ dependent bio-catalytic activity. Biosensors and Bioelectronics, 85 (2016): 240-246
- Akshath, U. S., Shubha, L. R., Bhatt, P., & Thakur, M. S. (2014). Quantum dots as optical labels for ultrasensitive detection of polyphenols. Biosensors and Bioelectronics,57,317-323
- Akshath, U. S., Vinayaka, A. C., & Thakur, M. S. (2012). Quantum dots as nano plug-in's for efficient NADH resonance energy routing. Biosensors and Bioelectronics,38(1),411-415
Patents
• A Colorimetric Reagent Kit for the detection of formaldehyde CSIR-CFTRI, Patent application number- 202211019411
All publication:
https://scholar.google.com/citations?user=-f785t4AAAAJ&hl=en&oi=ao
Conference/Journal workshops: 09
- Budhadev, D., Poole, E., Nehlmeier, I., Liu, Y., Hooper, J., Kalverda, E., Akshath, U.S., Hondow, N., Turnbull, W.B., Pohlmann, S. and Guo, Y., 2020. Glycan-Gold Nanoparticles as Multifunctional Probes for Multivalent Lectin-Carbohydrate Binding: Implications for Blocking Virus Infection and Nanoparticle Assembly. J. Am. Chem. Soc. 2020, 142, 42, 18022-18034
- Wang, Weili; Kong, Yifei; Jiang, Jun; Tian, Xin; Li, Shuang; Akshath, Uchangi; Tiede, Christian; Hondow, Nicole; Yu, Anchi; Guo, Yuan; Zhou, Dejian, Nanoscale, 2020. Photon induced quantum yield regeneration of cap-exchanged CdSe/CdS quantum rod for ratiometric biosensing and cellular imaging. Nanoscale, 2020, 12, 8647-8655, NC-1
- Sharma, R., Akshath, U.S., Bhatt, P., & Raghavarao, K. S. M. S. (2019). Fluorescent aptaswitch for chloramphenicol detection-Quantification enabled by immobilization of aptamer. Sensors and Actuators B: Chemical, 1 July 2019, 290, 110-117, NC-1
- Akshath, U.S., and Praveena Bhatt., (2017). Supramolecular nano-sniffers for ultrasensitive detection of formaldehyde. Biosensors & Bioelectronics, 100, 15 February 2018, 201-207, NC-2
- Akshath, U.S., and Praveena Bhatt. (2016) Gold nanoparticle synthesis coupled to fluorescence turn-on for sensitive detection of formaldehyde using formaldehyde dehydrogenase"- RSC Advances, 6(60), pp.54777-54784-NC-5
- Akshath, U.S., and Praveena Bhatt. (2016). Tunneling of redox enzymes to design nano-probes for monitoring NAD+ dependent bio-catalytic activity. Biosensors and Bioelectronics, 85 (2016): 240-246, NC-9
- Akshath, U.S., Shubha, L. R., Bhatt, P., & Thakur, M. S. (2014). Quantum dots as optical labels for ultrasensitive detection of polyphenols. Biosensors and Bioelectronics, 57, 317-323-NC-30
- Akshath, U.S., Vinayaka, A. C., & Thakur, M. S. (2012). Quantum dots as nano plug-in's for efficient NADH resonance energy routing. Biosensors and Bioelectronics, 38(1), 411-415-NC-15
Conference publications-09
Undergraduate-
Biochemistry
Postgraduate-
Bio-physical principles and Bio-analytical Techniques, Biochemistry
Biochemistry
Postgraduate-
Bio-physical principles and Bio-analytical Techniques, Biochemistry
- Polyvalent multifunctional core-shell satellites for ultrasensitive detection of target nucleic acids-a multiplexed approach-2021-2024, Funded by UGC-Faculty research promotion scheme, Start-up-Grant, Budget ₹10,00,000/-
- Target-induced Core-shell satellite structures: Creating a polyvalent multifunctional platform for multiplexed detection of nucleic acids, DST-SERB-SRG/2021/000202, 2021-2023, ₹32,70,340/-
- Development of a paper-based point-of-care biosensor for detection of heavy metal poisoning, ICMR, 2022-18279/F2, 2023-2026, ₹35,48,395/-
- Polyvalent multifunctional core-shell satellites for ultrasensitive detection of target nucleic acids-a multiplexed approach NUFR1 - Nitte University Faculty Start-up Research Grant, 2021-2023, Budget ₹1,50,000/-
Research Highlights
- Fluorescent disease sniffers, doi:10.1038/nindia.2012.121; Published online 23 August 2012, Nature India
- Optical sensor to detect dietary polyphenols, doi:10.1038/nindia.2014.49; Published online 16 April 2014, Nature India
DR. NEETHA NIRUPAM JATHANNA
- Designation Women Scientist -DBT BioCARe
- Email nirupam.neetha@nitte.edu.in
- Contact No. 8496034630
- Joining date
My area of research involves the isolation of novel strains of bacteria from ethnomedicinal plants and their application in the degradation process of various contaminants. Further, I also study the safety of the strain isolated and understand if these endophytic bacterial or fungal strains are safe for the environment.
Environmental biotechnology, Bioprocess technology bioremediation of contaminants, oil degradation, and toxicity assessment using biological systems are my areas of experimentation oriented towards contributing to the UN sustainable goal 3; 6;9;11; 15;13, and 14.
The purpose of my research is oriented towards developing sustainable methods to tackle the upcoming environmental problems concerned with pollutants and their toxicity.
- Doctor of Philosophy (Biotechnology), Visvesvaraya Technological University, Belgaum, Karnataka, April-2021
- Master of Science in biotechnology, Kuvempu University-2012
- Women Scientist -DBT BioCARe; Nitte University Centre for Science Education and Research; 01-01-2024 -2026
- Research Associate; Nitte University Centre for Science Education and Research; 04-11-2021 to 31-12-2023
- Research Coordinator; Sri Dharmasthala Manjunatheshwara College (Autonomous), Ujire; 08-02-2021 to 11-11-2021.
- Junior Research Fellow (JRF); Clinical Embryology, Kasturba Medical College, MAHE; 02-06-2014 to 02-12-2014
- Phyto-symbionts and their applications
- Bioremediation and assessment of metabolite toxicity
- Anti-bacterial and anti-fungal metabolites of endophytes
AWARD
DST- AWSAR [AUGMENTING WRITING SKILLS FOR ARTICULATING RESEARCH] Topic: "Bacterial Endophytes: Nature's Hidden Battalion against Environmental Pollution"
Fellowship
NITTE TRUST FELLOWSHIP -2015-2018 DBT-BioCARe Women scientist-07-12-2023 (3 years)
DST- AWSAR [AUGMENTING WRITING SKILLS FOR ARTICULATING RESEARCH] Topic: "Bacterial Endophytes: Nature's Hidden Battalion against Environmental Pollution"
Fellowship
NITTE TRUST FELLOWSHIP -2015-2018 DBT-BioCARe Women scientist-07-12-2023 (3 years)
• Member of student welfare committee, NUCSER
• Member, Women cell -NUCSER
- Neetha, J. N*, Girish Kumar Krishnamurthy, Mahendra Gowdru Srinivasa, Bilachi S. Ravindranath, Nidhi G Shetty (2024) Deciphering Phyto-Fungal dye concoction mitigation, degraded metabolite analysis, and assessment of ecotoxicity: Journal of Environmental Chemical Engineering: Impact: 7.7 (Accepted for publication)
- Neetha, J. N*., Kumar, G., Gopal, J., Hegde, S., Concepta, L., Ravindranath, B. S., & Gowdru, M. (2023). Phyto-bacterial biosorption of basic fuchsine : A self-sustainable approach towards biomitigation of contaminant of emerging concern. Journal of Environmental Chemical Engineering, 11(2), 109330. https://doi.org/10.1016/j.jece.2023.109330. Impact: 7.7
- Keerthana, S. P. R. K. V, Sangam, P. A., Vinayaka, K. S., & Neetha. (2021). Statistical optimisation of saccharification process using Amorphophallus paeoniifolius tubers into fermentable sugars for bioethanol production in stirred tank batch reactor ( STBR ). Biomass Conversion and Biorefinery, 0123456789. https://doi.org/10.1007/s13399-021-01748-8. Impact: 4.0
- Neetha, J. N*., Ujwal, P., Kumar, K. G., Chidananda, B., & Goveas, L. (2021). Aerobic biodegradation and optimization of 2 , 4-Dichlorophenoxyacetic acid by E . hormaechei subsp . Xiangfangensis and assessment of biodegraded metabolite toxicity. Environmental Technology & Innovation, 24, 1-15. https://doi.org/10.1016/j.eti.2021.102055. Impact: 7.1
- Neetha, J. N., Sandesh, K., Kumar, K. G., Chidananda, B., & Ujwal, P. (2019). Optimization of Direct Blue-14 dye degradation by Bacillus fermus (Kx898362) an alkaliphilic plant endophyte and assessment of degraded metabolite toxicity. Journal of Hazardous Materials, 364, 742-751. https://doi.org/10.1016/j.jhazmat.2018.10.074. Impact: 13.6
- Neetha, J. N., Ujwal, P., Sandesh, K., Santhosh, H., & Girish, K. (2018). Aerobic biodegradation of Acid Blue-9 dye by Bacillus fermus Isolated from Annona reticulata. Environmental Technology and Innovation, 11, 253-261. https://doi.org/10.1016/j.eti.2018.06.007. Impact: 7.7
- Applications Benefitting Health; Editors: K. Arunkumar, A. Arun, Rathinam Raja, Ramasamy Palaniappan; Algae Materials., Chapter 25: Phytoremediation: Algae-based bioremediation. Rachel Carmelita Mathias, Sharanya Kushalan, Himamshu Hegde, Neetha Nirupam Jathanna, Sowmya Sharada P and Smitha Hegde ISBN: 9780443188169. Date of publication: February 17, 2023
Google scholar: https://scholar.google.co.in/citations?user=gxwjfiEAAAAJ&hl=en
Scopus: https://www.scopus.com/authid/detail.uri?authorId=58083481900
PhD students: None
PG Students: None
UG Students: 1
PG Students: None
UG Students: 1
Undergraduate-
Biosafety and Bioethics, Environmental science
Postgraduate- Environmental and plant biotechnology, Bioprospecting and drug discovery, Bioprocess and fermentation technology, Microbial physiology
Postgraduate- Environmental and plant biotechnology, Bioprospecting and drug discovery, Bioprocess and fermentation technology, Microbial physiology
Extramural Funding
• DBT-BioCARe- 6th call "Eliciting degradation of contamination of emerging concern (CEC) using a novel endophytic bacterial consortium" 07-12-2023 to 07-12-2026
Intramural Funding
• NUSR-2024
• DBT-BioCARe- 6th call "Eliciting degradation of contamination of emerging concern (CEC) using a novel endophytic bacterial consortium" 07-12-2023 to 07-12-2026
Intramural Funding
• NUSR-2024
